Molecular cloning of genes encoding oncosphere proteins reveals conservation of modular protein structure in cestode antigens

Molecular and Biochemical Parasitology

Volumn 127, Issue 2, 2003, Pages 193-198

  Gauci, Charles ^a   Lightowlers, Marshall W ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Antigen; Cysticercosis; Echinococcus; Gene; Oncosphere; Taenia; Vaccine

Indexed keywords

ANTIGEN; FIBRONECTIN; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; ECHINOCOCCUS GRANULOSUS; ECHINOCOCCUS MULTILOCULARIS; EXON; GENE; GENE STRUCTURE; GENETIC CONSERVATION; INTRON; MOLECULAR CLONING; NONHUMAN; PARASITE SURVIVAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; TAENIA OVIS; TAENIA SAGINATA; TAENIA SOLIUM;

CESTODA; ECHINOCOCCUS; ECHINOCOCCUS GRANULOSUS; ECHINOCOCCUS MULTILOCULARIS; OVIS; TAENIA; TAENIA OVIS; TAENIA SAGINATA; TAENIA SOLIUM;

EID: 0037417207     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(03)00005-7     Document Type: Article

References (28)

1. White A.C. Neurocysticercosis: updates on epidemiology, pathogenesis, diagnosis, and management. Annu. Rev. Med. 51:2000;187-206.
2. Rickard M.D., Williams J.F. Hydatidosis/cysticercosis: immune mechanisms and immunization against infection. Adv. Parasitol. 21:1982;229-296.
3. Johnson K.S., Harrison G.B., Lightowlers M.W., O'Hoy K.L., Cougle W.G., Dempster R.P.et al. Vaccination against ovine cysticercosis using a defined recombinant antigen. Nature. 338(6216):1989;585-587.
4. Waterkeyn J., Gauci C., Cowman A., Lightowlers M. Sequence analysis of a gene family encoding Taenia ovis vaccine antigens expressed during embryogenesis of eggs. Mol. Biochem. Parasitol. 86(1):1997;75-84.
5. Harrison G.B., Heath D.D., Dempster R.P., Gauci C., Newton S.E., Cameron W.G.et al. Identification and cDNA cloning of two novel low molecular weight host-protective antigens from Taenia ovis oncospheres. Int. J. Parasitol. 26(2):1996;195-204.
6. Lightowlers M.W., Rolfe R., Gauci C.G. Taenia saginata vaccination against cysticercosis in cattle with recombinant oncosphere antigens. Exp. Parasitol. 84(3):1996;330-338.
7. Gauci C.G., Flisser A., Lightowlers M.W. A Taenia solium oncosphere protein homologous to host-protective Taenia ovis and Taenia saginata 18 kDa antigens. Int. J. Parasitol. 28(5):1998;757-760.
8. Gauci C.G., Lightowlers M.W. Alternative splicing and sequence diversity of transcripts from the oncosphere stage of Taenia solium with homology to the 45W antigen of Taenia ovis. Mol. Biochem. Parasitol. 112(2):2001;173-181.
9. Lightowlers M.W., Lawrence S.B., Gauci C.G., Young J., Ralston M.J., Maas D.et al. Vaccination against hydatidosis using a defined recombinant antigen. Parasite Immunol. 18(9):1996;457-462.
10. Chow C., Gauci C.G., Cowman A.F., Lightowlers M.W. A gene family expressing a host-protective antigen of Echinococcus granulosus. Mol. Biochem. Parasitol. 118(1):2001;83-88.
11. Gauci C., Merli M., Muller V., Chow C., Yagi K., Mackenstedt U.et al. Molecular cloning of a vaccine antigen against infection with the larval stage of Echinococcus multilocularis. Infect. Immun. 70(7):2002;3969-3972.
12. Lightowlers M.W., Flisser A., Gauci C.G., Heath D.D., Jensen O., Rolfe R. Vaccination against cysticercosis and hydatid disease. Parasitol. Today. 16(5):2000;19l-196.
13. Waterkeyn J.G., Lightowlers M.W., Coppel R., Cowman A.F. Characterization of the gene family encoding a host-protective antigen of the tapeworm Taenia ovis. Mol. Biochem. Parasitol. 73(1/2):1995;123-131.
14. McManus D.P., Knight M., Simpson A.J. Isolation and characterisation of nucleic acids from the hydatid organisms, Echinococcus spp. (Cestoda). Mol. Biochem. Parasitol. 16(3):1985;251-266.
15. Puissant C., Houdebine L.M. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques. 8(2):1990;148-149.
16. Stevenson P. Observations on the hatching and activation of fresh Taenia saginata eggs. Ann. Trop. Med. Parasitol. 77(4):1983;399-404.
17. Rajasekariah G.R., Rickard M.D., Mitchell G.F. Density-gradient separation of Taenia pisiformis oncospheres. J. Parasitol. 66(2):1980;355-356.
18. Southern E.M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98(3):1975;503-517.
19. Decker C.J., Parker R. Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts. Curr. Opin. Cell Biol. 7(3):1995;386-392.
20. Patthy L. Genome evolution and the evolution of exon-shuffling - a review. Gene. 238(1):1999;103-114.
21. Bonay P., Gonzalez L.M., Benitez L., Foster M., Harrison L.J., Parkhouse R.M.et al. Genomic and functional characterisation of a secreted antigen of Taenia saginata oncospheres. Mol. Biochem. Parasitol. 121(2):2002;269-273.
22. Patthy L. Introns and exons. Curr. Opin. Struct. Biol. 4:1994;383-392.
23. Ponting C.P., Schultz J., Milpetz F., Bork P. SMART: identification and annotation of domains from signalling and extracellular protein sequences. Nucleic Acids Res. 27(1):1999;229-232.
24. Patthy L. Homology of a domain of the growth hormone/prolactin receptor family with type III modules of fibronectin. Cell. 61(1):1990;13-14.
25. Kossiakoff A.A., Somers W., Ultsch M., Andow K., Muller Y.A., De Vos A.M. Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors. Protein Sci. 3(10):1994;1697-1705.
26. Bole-Feysot C., Goffin V., Edery M., Binart N., Kelly P.A. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr. Rev. 19(3):1998;225-268.
27. Morales-Montor J., Baig S., Mitchell R., Deway K., Hallal-Calleros C., Damian R.T. Immunoendocrine interactions during chronic cysticercosis determine male mouse feminization: role of IL-6. J. Immunol. 167(8):2001;4527-4533.
28. Morales J., Velasco T., Tovar V., Fragoso G., Fleury A., Beltran C.et al. Castration and pregnancy of rural pigs significantly increase the prevalence of naturally acquired Taenia solium cysticercosis. Vet. Parasitol. 108(1):2002;41.