Proline-catalyzed asymmetric α-amination of aldehydes and ketones - An astonishingly simple access to optically active α-hydrazino carbonyl compounds

Angewandte Chemie - International Edition

Volumn 42, Issue 9, 2003, Pages 975-978

  Duthaler, Rudolf O ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Amination; Azodicarboxylates; Catalysis; Enantioselectivity; Proline

Indexed keywords

ALDEHYDES; CARBOXYLATION; KETONES; METHANE; THERMAL EFFECTS;

ROOM TEMPERATURE;

CATALYSIS;

ACETONE; ACETONITRILE; ALDEHYDE DERIVATIVE; AZIDE; CARBONYL DERIVATIVE; DICARBOXYLIC ACID DERIVATIVE; DICHLOROMETHANE; DIMETHYLAMINE; GLYOXYLIC ACID DERIVATIVE; KETONE DERIVATIVE; NITROSO DERIVATIVE; OXAZOLIDINONE DERIVATIVE; PERMANGANATE POTASSIUM; PROLINE; SODIUM HYDROXIDE; ZINC;

ALDOL REACTION; AMINATION; AMINOHYDROXYLATION; ARTICLE; CATALYSIS; CATALYST; CHROMATOGRAPHY; CYCLIZATION; ENANTIOMER; ENANTIOSELECTIVITY; MANNICH REACTION; OXIDATION; ROOM TEMPERATURE; THERMODYNAMICS;

ALDEHYDES; AMINATION; AMINES; CATALYSIS; KETONES; MOLECULAR STRUCTURE; PROLINE; STEREOISOMERISM;

EID: 0037416272     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200390283     Document Type: Article

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