A new synthetic route to compounds of the AFDX-type with affinity to muscarinic M2-receptor

Tetrahedron

Volumn 59, Issue 6, 2003, Pages 781-787

  Holzgrabe, Ulrike ^a   Heller, Eberhard ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

AFDX 384; AFDX 384 W84 hybride; Microwave assisted reaction; W84

Indexed keywords

1,6 HEXAMETHYLENEBIS[DIMETHYL(3 PHTHALIMIDOPROPYL)AMMONIUM BROMIDE]; [3 (1,3 DIOXO 1,3 DIHYDROISOINDOL 2 YL)PROPYL]DIMETHYL [6 [[1 [2 [(6 OXO 5,6 DIHYDROBENZO[E]PYRIDO[3,2 B][1,4]DIAZEPINE 11 CARBONYL)AMINO]ETHYL]PIPERIDIN 2 YLMETHYL]PROPYLAMINO]HEXYL]AMMONIUM BROMIDE; BENZODIAZEPINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR ANTAGONIST; N [2 [2 (DIPROPYLAMINOMETHYL) 1 PIPERIDYL]ETHYL] 5,11 DIHYDRO 6 OXO 6H PYRIDO[2,3 B][1,4]BENZODIAZEPINE 11 CARBOXAMIDE; PHTHALIC ANHYDRIDE; PHTHALIMIDE; PIPECOLIC ACID; PIPERIDINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE RADIATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; REPRODUCIBILITY;

EID: 0037415525     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(02)01623-X     Document Type: Article

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