Preparation of purified acylglycerols of eicosapentaenoic acid and docosahexaenoic acid and their re-esterification with conjugated linoleic acid

Enzyme and Microbial Technology

Volumn 32, Issue 1, 2003, Pages 49-58

  Torres, Carlos F ^a   Nettekoven, Tammy Joy ^a   Hill Jr , Charles G ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Conjugated linoleic acid; Ethanolysis; Lipase; Molecular distillation; Omega 3 fatty acids; Re esterification

Indexed keywords

CATALYSIS; DISTILLATION; ESTERIFICATION; ESTERS; FATTY ACIDS; GLYCEROL;

ETHANOLYSIS;

ENZYMES;

ACYLGLYCEROL; BACTERIAL ENZYME; DOCOSAHEXAENOIC ACID; ESTER; FATTY ACID; FISH OIL; GLYCEROL DERIVATIVE; ICOSAPENTAENOIC ACID; LINOLEIC ACID; MENHADEN OIL; OMEGA 3 FATTY ACID; TRIACYLGLYCEROL;

ARTICLE; BIOCATALYST; BURKHOLDERIA CEPACIA; CONJUGATION; CONTROLLED STUDY; DISTILLATION; DRUG PURIFICATION; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN;

BURKHOLDERIA CEPACIA; PSEUDOMONAS;

EID: 0037413387     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(02)00248-X     Document Type: Article

References (20)

1. Willis W.M., Lencki R.W., Marangoni A.G. Lipid modification strategies in the production of nutritionally functional fats and oils. Crit. Rev. Food Sci. Nutr. 38:1998;1-36.
2. Sardesai V.M. Nutritional role of polyunsaturated fatty acids. J. Nutr. Biochem. 3:1992;154-166.
3. Anonymous. Nutritional Aspects of Fish. British Nutrition Foundation briefing paper No. 10. London: British Nutrition Foundation; 1993.
4. Anonymous. Recommendations for the essential fatty acid requirements for infant formulae. Int. Soc. Study Fatty Acids Lipids News Lett. 1994;1:4-5.
5. Chin S.F., Liu W., Storkson J.M., Ha Y.L., Pariza M.W. Dietary sources of conjugated dienoic isomers of linoleic acid, a newly recognized class of anticarcinogens. J. Food Comp. Anal. 5:1992;185-197.
6. Sehat N., Yurawecz M.P., Roach J.A.G., Mossoba M., Kramer J.K.G., Ku Y. Silver ion high-performance liquid chromatographic separation and identification of conjugated linoleic acid isomers. Lipids. 33:1998;217-221.
7. Ha Y.L., Grimm N.K., Pariza M.W. Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis. 8:1987;1881-1887.
8. Lee K.N., Kritchevsky D., Pariza M.W. Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis. 108:1994;19-25.
9. Chin S.F., Storkson J.M., Albright K.J., Cook M.E., Pariza M.W. Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency. J. Nutr. 124:1994;2344-2349.
10. Marangoni A.G., Rousseau D. Engineering triacylglycerols: the role of interesterification. Trends Food Sci. Technol. 6:1995;329-335.
11. Irimescu R., Furihata K., Hata K., Iwasaki Y., Yamane T. Utilization of reaction medium-dependent regiospecificity of Candida antarctica lipase (Novozym 435) for the synthesis of 1,3-dicapryloyl-2-docosahexaenoyl (or eicosapentaenoyl) glycerol. J. Am. Oil Chem. Soc. 78:2001;285-289.
12. Willis W.M., Marangoni A.G. Assessment of lipase- and chemically catalyzed lipid modification strategies for the production of structured lipids. J. Am. Oil Chem. Soc. 76:1999;443-450.
13. Kawashima A., Shimada Y., Yamamoto M., Sugihara A., Nagao T., Komemushi S., Tominaga Y. Enzymatic synthesis of high-purity structured lipids with caprylic acid at 1,3-positions and polyunsaturated fatty acid at 2-position. J. Am. Oil Chem. Soc. 78:2001;611-616.
14. Breivik H., Haraldsson G.G., Kristinsson B. Preparation of highly purified concentrates of eicosapentaenoic acid and docosahexaenoic acid. J. Am. Oil Chem. Soc. 74:1997;1425-1429.
15. Rice K.E., Watkins J., Hill C.G. Hydrolysis of menhaden oil by a Candida cylindracea lipase immobilized in a hollow-fiber reactor. Biotechnol. Bioeng. 63:1999;33-45.
16. Garcia H.S., Arcos J.A., Ward D.J., Hill C.G. Synthesis of glycerides containing n-3 fatty acids and conjugated linoleic acid by solvent-free acidolysis of fish oil. Biotechnol. Bioeng. 70:2000;587-591.
17. Torres C.F., Hill C.G. Lipase-catalyzed acidolysis of menhaden oil with conjugated linoleic acid: effect of water content. Biotechnol. Bioeng. 78:2002;509-516.
18. Malaprade L. Oxidation of some polyalcohols by periodic acid: applications. Compt. Rend. 186:1928;382-384.
19. Williams J.P., Khan M.U., Wong D. A simple technique for the analysis of positional distribution of fatty acids on di-, and triacylglycerols using lipase and phospholipase a2. J. Lipid Res. 36:1995;1407-1412.
20. Xu X.B., Skands A., Adler-Nissen J. Purification of specific structured lipids by distillation: effects on acyl migration. J. Am. Oil Chem. Soc. 78:2001;715-718.