Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: Synthesis, biological evaluation, and comparative molecular field analysis

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 1, 2003, Pages 123-138

  Roma, Giorgio ^a   Di Braccio, Mario ^a   Carrieri, Antonio ^b   Grossi, Giancarlo ^a   Leoncini, Giuliana ^a   Grazia Signorello, Maria ^a   Carotti, Angelo ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

10 METHYL 2 (1 PIPERAZINYL) 4H NAPHTHO[2,3 B]PYRAN 4 ONE; 10 METHYL 4 (1 PIPERAZINYL) 2H NAPHTHO[2,3 B]PYRAN 2 ONE; 2 (1 PIPERAZINYL) 4H NAPHTHO[2,3 B]PYRAN 4 ONE; 2 METHYL 7 (1 PIPERAZINYL) 5H THIAZOLO[3,2 A]PYRIMIDIN 5 ONE; 2,3 DIMETHYL 7 (1 PIPERAZINYL) 5H THIAZOLO[3,2 A]PYRIMIDIN 5 ONE; 3 METHYL 7 (1 PIPERAZINYL) 5H THIAZOLO[3,2 A]PYRIMIDIN 5 ONE; 4 (1 PIPERAZINYL) 2H NAPHTHO[2,3 B]PYRAN 2 ONE; 6 METHYL 2 (1 PIPERAZINYL) 4H PYRIMIDO[2,1 B]BENZOTHIAZOL 4 ONE; 7 BENZYLOXY 8 METHYL 2 (1 PIPERAZINYL) 4H 1 BENZOPYRAN 4 ONE; 7 CHLORO 2 (1 PIPERAZINYL) 4H PYRIMIDO[2,1 B]BENZOXAZOL 4 ONE; 8 (1 PIPERAZINYL) 6H 1,3 DIOXOLO[4,5 G][1]BENZOPYRAN 6 ONE; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CALCIMYCIN; CALCIUM IONOPHORE; CHROMONE DERIVATIVE; COLLAGEN; COUMARIN DERIVATIVE; PYRIMIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NORMAL HUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

ADENOSINE DIPHOSPHATE; CALCIMYCIN; CHROMONES; COLLAGEN; COUMARINS; ELECTROSTATICS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PYRIMIDINONES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STEREOISOMERISM;

EID: 0037413352     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00307-3     Document Type: Article

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