Change in muscarinic modulation of transmitter release in the rat urinary bladder after spinal cord injury

Neurochemistry International

Volumn 43, Issue 1, 2003, Pages 73-77

  Somogyi, George T ^a,b   Zernova, Ganna V ^a   Yoshiyama, Mitsuharu ^a   Rocha, Jeova N ^a   Smith, Christopher P ^a   De Groat, William C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

ACh release; Pre synaptic muscarinic receptors; Spinal cord injury; Spinal cord transaction; Urinary bladder

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ACETYLCHOLINE; ATROPINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M3 RECEPTOR; PIRENZEPINE;

ACETYLCHOLINE RELEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; CHOLINERGIC NERVE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTROSTIMULATION; FACILITATION; FEMALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SPINAL CORD INJURY; SPINAL CORD TRANSSECTION; THORACIC SPINE;

ANIMALS; ATROPINE; ELECTRIC STIMULATION; FEMALE; MUSCARINIC ANTAGONISTS; NEUROTRANSMITTER AGENTS; PIPERIDINES; PIRENZEPINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MUSCARINIC M3; RECEPTORS, MUSCARINIC; SPINAL CORD INJURIES; URINARY BLADDER; URINARY BLADDER, NEUROGENIC;

EID: 0037411551     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(02)00193-6     Document Type: Article

References (19)

1. 3H -acetylcholine secretion in the guinea-pig urinary bladder in vitro J. Pharmacol. Exp. Ther. 274:1995;458-468.
2. Caulfield M.P., Birdsall N.J.M. Interantional Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol. Rev. 50:1998;279-290.
3. 2 muscarinic receptors in trachea and ileum of diabetic rats. Br. J. Pharmacol. 135:2002;1355-1362.
4. 3H ]acetylcholine release in the rat urinary bladder J. Pharmacol. Exp. Ther. 283:1997;750-756.
5. de Groat W.C. Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury. Paraplegia. 33:1995;493-505.
6. de Groat W.C., Booth A.M., Yoshimura N.,1993. Neurophysiology of micturition and its modification in animal models of human disease. In: Maggi C.A. (Ed). The Autonomic Nervous System, vol. 3, Nervous Control of the Urogenital System, 1st ed. Harwood Academic Publishers, London, pp. 227-290.
7. Eglen R.M., Hegde S.S., Watson N. Muscarinic receptor subtypes and smooth muscle function. Pharm. Rev. 48:1996;531-565.
8. 2 muscarinic receptor function in antigen-chellenged guinea-pigs. Am. J. Resp. Cell Mol. Biol. 12:1995;320-328.
9. Kruse M.N., Bray L.A., de Groat W.C. Influence of spinal cord injury on the morphology of bladder afferent and efferent neurons. J. Auton. Nerv. Syst. 54:1995;215-224.
10. Somogyi G.T., de Groat W.C. Evidence for inhibitory nicotinic and facilitatory muscarinic receptors in cholinergic nerve terminals of the rat urinary bladder. J. Auton. Nerv. Syst. 37:1992;89-98.
11. 1 muscarinic receptor-mediated facilitation of acetylcholine release in the rat urinary bladder. J. Physiol. 480(1):1994;81-89.
12. 1 adrenoceptors in the rat urinary bladder. Br J. Pharmacol. 114:1995;1710-1716.
13. Somogyi G.T., Vizi E.S. Evidence that cholinergic axon terminals are equipped with both muscarinic and adenosine receptors. Brain Res. Bull. 21:1988;575-579.
14. Somogyi G.T., Zernova G.V., Yoshiyama M., Yamamoto T., De Groat W.C. Frequency dependence of muscarinic facilitation of transmitter release in urinary bladder strips from neurally intact or chronic spinal cord transected rats. Br. J. Pharmacol. 125:1998;241-246.
15. Steers W.D., Kolbeck S., Creedon D., Tuttle J.B. Nerve growth factor in the urinary bladder of the adult regulates neronal form and function. J. Clin. Invest. 88:1991;1709-1715.
16. Tran L.V., Somogyi G.T., de Groat W.C. Inhibitory effect of neuropeptide Y on cholinergic and adrenergic transmissions in the rat urinary bladder body, bladder base and urethra. Am. J. Physiol. 266:1994;R1411-R1417.
17. Vizzard M.A. Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction. Exp. Neurol. 161:2000;273-284.
18. Wang P., Luthin G.R., Ruggieri M.R. Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J. Pharmacol. Exp. Ther. 273:1995;959-966.
19. Zernova, G.V., Yoshiyama, M., Booth, A.M., de Groat, W.C., Somogyi, G.T., 1996. Frequency dependence of muscarinic facilitation of transmitter release in urinary bladder strips from neurally intact or chronic spinal cord transected rats, Society for Neuroscience Abstacts 22, 93.