Immunoglobulin light chains in uremia

Kidney International, Supplement

Volumn 63, Issue 84, 2003, Pages

  Cohen, Gerald ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Apoptosis; Hemodialysis; Light chain deposition; Neutrophils

Indexed keywords

BENCE JONES PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

APOPTOSIS; BACTERIAL INFECTION; CELL FUNCTION; CONCENTRATION RESPONSE; CONFERENCE PAPER; DIAFILTRATION; HEMODIALYSIS; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEPOSITION; IMMUNOMODULATION; INFECTION SENSITIVITY; KIDNEY FAILURE; KIDNEY METABOLISM; LYMPHOPROLIFERATIVE DISEASE; NEUTROPHIL; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; UREMIA; B LYMPHOCYTE; BLOOD; IMMUNOLOGY; KIDNEY; REVIEW;

B-LYMPHOCYTES; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; KIDNEY; UREMIA;

EID: 0037408116     PISSN: 00986577     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.63.s84.8.x     Document Type: Conference Paper

References (23)

1. HANNAM-HARRIS AC, GORDON J, SMITH JL: Immunoglobulin synthesis by neoplastic B lymphocytes: Free light chain synthesis as a marker of B cell differentiation. J Immunol 125:2177-2181, 1980
2. SOLLING K: Free light chains of immunoglobulins. Scand J Clin Lab Invest (Suppl 157):1-83, 1981
3. MAACK T, JOHNSON V, KAU ST, et al: Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review. Kidney Int 16:251-270, 1979
4. BATUMAN V, VERROUST PJ, NAVAR GL, et al: Myeloma light chains are ligands for cubilin (gp280). Am J Physiol 275:F246-254, 1998
5. CHRISTENSEN EI, BIRN H: Megalin and cubilin: Synergistic endocytic receptors in renal proximal tubule. Am J Physiol Renal Physiol 280:F562-573, 2001
6. WAKASUGI K, SASAKI M, SUZUKI M, et al: Increased concentrations of free light chain lambda in sera from chronic hemodialysis patients. Biomater Artif Cells Immobilization Biotechnol 19:97-109, 1991
7. COHEN G, RUDNICKI M, SCHMALDIENST S, HORL WH: Effect of dialysis on serum/plasma levels of free immunoglobulin light chains in end-stage renal disease patients. Nephrol Dial Transplant 17: 879-883, 2002
8. SCHIFFL H, D'AGOSTINI B, HELD E: Removal of beta 2-microglobulin by hemodialysis and hemofiltration: A four year follow up. Biomater Artif Cells Immobilization Biotechnol 20:1223-1232, 1992
9. MACHIGUCHI T, TAMURA T, YOSHIDA H: Efficacy of haemodiafiltration treatment with PEPA dialysis membranes in plasma free light chain removal in a patient with primary amyloidosis. Nephrol Dial Transplant 17:1689-1691, 2002
10. VANHOLDER R, ARGILES A, BAURMEISTER U, et al: Uremic toxicity: Present state of the art. Int J Artif Organs 24:695-725, 2001
11. COHEN G, HAAG-WEBER M, MAI B, et al: Effect of immunoglobulin light chains from hemodialysis and continuous ambulatory peritoneal dialysis patients on polymorphonuclear leukocyte functions. J Am Soc Nephrol 6:1592-1599, 1995
12. DESCAMPS-LATSCHA B, HERBELIN A, NGUYEN AT, et al: Immune system dysregulation in uremia. Semin Nephrol 14:253-260, 1994
13. JACOBSON DR, ZOLLA-PAZNER S: Immunosuppression and infection in multiple myeloma. Semin Oncol 13:282-290, 1986
14. HEINZELMANN M, MERCER-JONES MA, PASSMORE JC: Neutrophils and renal failure. Am J Kidney Dis 34:384-399, 1999
15. SAVILL J, FADOK V, HENSON P, HASLETT C: Phagocyte recognition of cells undergoing apoptosis. Immunol Today 14:131-136, 1993
16. MORRISON DC, JACOBS DM: Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. Immunochemistry 13:813-818, 1976
17. WALL JS, AYOUB FM, O'SHEA PS: A study of the interactions of an immunoglobulin light chain with artificial and B-lymphocyte membranes. Front Biosci 1:46-58, 1996
18. DEREI S, CHOMILIER J, HUANG DB, et al: Molecular modeling of immunoglobulin light chains implicates hydrophobic residues in non-amyloid light chain deposition disease. Protein Eng 10:1191-1197, 1997
19. KAGIMOTO T, NAKAKUMA H, HATA H, et al: Differential glycosylation of Bence Jones protein and kidney impairment in patients with plasma cell dyscrasia. J Lab Clin Med 129:217-223, 1997
20. NICASTRI AL, PRADO MJ, DOMINGUEZ WV, PRADO EB: Nephrotoxicity of Bence-Jones proteins: Interference in renal epithelial cell acidification. Braz J Med Biol Res 35:357-360, 2002
21. GUAN S, EL-DAHR S, DIPP S, BATUMAN V: Inhibition of Na-K-ATPase activity and gene expression by a myeloma light chain in proximal tubule cells. J Investig Med 47:496-501, 1999
22. ZHU L, HERRERA GA, MURPHY-ULLRICH JE, et al: Pathogenesis of glomerulosclerosis in light chain deposition disease. Role for transforming growth factor-beta. Am J Pathol 147:375-385, 1995
23. KIM YS, CAPE SP, CHI E, et al: Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains. J Biol Chem 276:1626-1633, 2001