Evaluation of newly developed ELISA using "MESACUP-2 Test Mitochondrial M2" kit for the diagnosis of primary biliary cirrhosis

Clinical Biochemistry

Volumn 36, Issue 3, 2003, Pages 203-210

  Kadokawa, Yoshiko ^a   Omagari, Katsuhisa ^a   Hazama, Hiroaki ^a   Ohba, Kazuo ^a   Masuda, Jun Ichi ^a   Kinoshita, Hideki ^a   Hayashida, Kenji ^a   Isomoto, Hajime ^a   Mizuta, Yohei ^a   Murase, Kunihiko ^a   Murata, Ikuo ^b   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

2 oxo acid dehydrogenase complex; Antimitochondrial antibody; Enzyme linked immunosorbent assay; Primary biliary cirrhosis

Indexed keywords

2 OXODEHYDROGENASE COMPLEX; ENZYME; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; MITOCHONDRION ANTIBODY; PYRUVATE DEHYDROGENASE COMPLEX; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBUNIT; EVALUATION; FEMALE; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; INTERMETHOD COMPARISON; JAPAN; MAJOR CLINICAL STUDY; MALE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; SERODIAGNOSIS;

EID: 0037407161     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(02)00439-3     Document Type: Article

References (17)

1. Kaplan M.M. Primary biliary cirrhosis. N Eng J Med. 335:1996;1570-1580.
2. Moteki S., Leung P.S.C., Coppel R.L., et al. Use of a designer triple expression hybrid clone for three different lipoyl domains for the detection of antimitochondrial autoantibodies. Hepatology. 24:1996;97-103.
3. Gershwin M.E., Mackay I., Coppel R., Nakanuma Y. Clinical, immunologic, and molecular features of primary biliary cirrhosis. Semin Clin Immunol. 7:1994;5-16.
4. Hazama H., Omagari K., Masuda J., et al. Automated enzymatic mitochondrial antibody assay for the diagnosis of primary biliary cirrhosis applications of a routine diagnostic tool for the detection of antimitochondrial antibodies . J Gastroenterol Hepatol. 17:2002;316-323.
5. Takemura M., Ohya K., Kojima K. Fundamental evaluation of "MESACUP-2 Test Mitochondrial M2" Jpn J Med Pharm Sci. 46:2001;809-816. (Japanese).
6. Hashimoto E., Shimada M., Hayashi N. Diagnosis significance of antimitochondrial M2 measurement by ELISA method using recombinant antigen in patients with primary biliary cirrhosis. Jpn J Med Pharm Sci. 46:2001;1031-1037. (Japanese).
7. Nakano T., Inoue K., Hirohara J., et al. Long-term prognosis of primary biliary cirrhosis (PBC) in Japan and analysis of the factors of stage progression in asymptomatic PBC (a-PBC). Hepatol Res. 22:2002;250-260.
8. Scheuer P.J., Lefkowitch J.H. Liver biopsy interpretation. 6th Edn:2000;W.B. Saunders, London.
9. Hazama H., Omagari K., Masuda J., et al. Serial changes in enzyme inhibitory antibody to pyruvate dehydrogenase complex during the course of primary biliary cirrhosis. J Clin Lab Anal. 14:2000;208-213.
10. Stanley C.J., Perham R.N. Purification of 2-oxo acid dehydrogenase multienzyme complexes from ox heart by a new method. Biochem J. 191:1980;147-154.
11. Kinoshita H., Omagari K., Matsuo I., Yamaguchi K., Ikuno N., Kohno S. Frequency of IgG, IgM, and IgA class autoantibodies against 2-oxo-acid dehydrogenase complex in 102 Japanese patients with primary biliary cirrhosis. Hepatol Res. 15:1999;163-171.
12. Kitami N., Komada T., Ishii H., et al. Immunological study of anti-M2 in antimitochondrial antibody-negative primary biliary cirrhosis. Intern Med. 34:1995;496-501.
13. Masuda J., Omagari K., Miyakawa H., et al. Clinical significance of positive immunoblotting but negative immunofluorescence for antimitochondrial antibodies in patients with liver diseases other than primary biliary cirrhosis. Autoimmunity. 35:2002;135-141.
14. Tanaka A., Miyakawa H., Luketic V.A.C., Kaplan M., Storch W.B., Gershwin M.E. The diagnostic value of anti-mitochondrial antibodies, especially in primary biliary cirrhosis. Cell Mol. 48:2002;295-299.
15. Miyakawa H., Tanaka A., Kikuchi K., et al. Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens. Hepatology. 34:2001;243-248.
16. Miyakawa H., Kikuchi K., Kitazawa E., Kawaguchi N. Anti-pyruvate dehydrogenase complex-E2 antibody immunoglobulin class switch from IgM to IgG in long-term follow-up patients with primary biliary cirrhosis. Hepatol Res. 22:2002;167-173.
17. Nishio A., Van de Water J., Leung P.S.C., et al. Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis. Hepatology. 25:1997;1085-1089.