Conformational states of the switch I region of Ha-ras-p21 in hinge residue mutants studied by fluorescence lifetime and fluorescence anisotropy measurements

Protein Science

Volumn 12, Issue 5, 2003, Pages 930-938

  Kuppens, Steven ^a   Hellings, Mario ^a   Jordens, Jan ^a   Verheyden, Stefan ^a   Engelborghs, Yves ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Conformational change; Fluorescence lifetimes; G proteins; Molecular switch; Ras protein

Indexed keywords

GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HA RAS P21 PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

ANISOTROPY; ARTICLE; CONFORMATIONAL TRANSITION; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; MOLECULAR DYNAMICS; MOLECULAR SWITCH; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; QUANTUM YIELD; STEADY STATE;

AMINO ACID SUBSTITUTION; FLUORESCENCE; FLUORESCENCE POLARIZATION; FLUOROMETRY; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HALF-LIFE; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS P21(RAS); TRYPTOPHAN;

EID: 0037407031     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0236303     Document Type: Article

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