Ste11p, a high-mobility-group box DNA-binding protein, undergoes pheromone- and nutrient-regulated nuclear-cytoplasmic shuttling

Molecular and Cellular Biology

Volumn 23, Issue 9, 2003, Pages 3253-3264

  Qin, Jian ^a   Kang, Wenfei ^a   Leung, Betty ^a   McLeod, Maureen ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HIGH MOBILITY GROUP B PROTEIN; LEPTOMYCIN B; PHEROMONE; PROTEIN 14 3 3; PROTEIN RAD24P; TRANSCRIPTION FACTOR STE11P; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CELL GROWTH; CELL LEVEL; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; DELETION MUTANT; GENE EXPRESSION; GENE TARGETING; HIGH MOBILITY GROUP BOX DOMAIN; MATING; NONHUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; NUCLEOCYTOPLASMIC TRANSPORT; NUTRIENT; NUTRIENT LIMITATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SCHIZOSACCHAROMYCES POMBE; YEAST CELL;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL CYCLE PROTEINS; CELL NUCLEUS; CONJUGATION, GENETIC; CULTURE MEDIA; CYTOPLASM; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GREEN FLUORESCENT PROTEINS; HMG-BOX DOMAINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KARYOPHERINS; LUMINESCENT PROTEINS; NITROGEN; NUCLEAR LOCALIZATION SIGNALS; PHEROMONES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0037405726     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.9.3253-3264.2003     Document Type: Article

References (51)

1. Alfa, C., P. Fantes, J. Hyams, M. McLeod, and E. Warbrick. 1993. Experiments with fission yeast. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
2. + controls the transition from mitotic division to meiosis in fission yeast. Curr. Genet. 10:297-311.
3. Bresch, C., G. Muller, and R. Egel. 1968. Genes involved in meiosis and sporulation of a yeast. Mol. Gen. Genet. 102:301-306.
4. Christophe, D., C. Christophe-Hobertus, and B. Pichon. 2000. Nuclear targeting of proteins: how many different signals? Cell Signal. 12:337-341.
5. Davey, J. 1998. Fusion of a fission yeast. Yeast 14:1529-1566.
6. 1 arrest in the fission yeast Schizosaccharomyces pombe. Curr. Genet. 26:105-112.
7. de Santa Barbara, P., B. Moniot, F. Poulat, and P. Berta. 2000. Expression and subcellular localization of SF-1, SOX9, WT1, and AMH proteins during early human testicular development. Dev. Dyn. 217:293-298.
8. Egel, R. 2000. Fission yeast on the brink of meiosis. Bioessays 22:854-860.
9. Ford, J. C., F. al-Khodairy, E. Fotou, K. S. Sheldrick, D. J. Griffiths, and A. M. Carr. 1994. 14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast. Science 265:533-535.
10. Gasca, S., J. Canizares, P. De Santa Barbara, C. Mejean, F. Poulat, P. Berta, and B. Boizet-Bonhoure. 2002. A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination. Proc. Natl. Acad. Sci. USA 99:11199-11204.
11. Grimm, C., J. Kohli, J. Murray, and K. Maundrell. 1988. Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement with the ura4 gene as a selectable marker. Mol. Gen. Genet. 215:81-86.
12. Grosschedl, R., K. Giese, and J. Pagel. 1994. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10:94-100.
13. Higuchi, T., Y. Watanabe, and M. Yamamoto. 2002. Protein kinase A regulates sexual development and gluconeogenesis through phosphorylation of the Zn finger transcriptional activator Rst2p in fission yeast. Mol. Cell. Biol. 22:1-11.
14. Iino, Y., and M. Yamamoto. 1985. Mutants of Schizosaccharomyces pombe which sporulate in the haploid state. Mol. Gen. Genet. 198:416-421.
15. 1 arrest in the mating partner. Genes Dev. 8:328-338.
16. Kitamura, K., S. Katayama, S. Dhut, M. Sato, Y. Watanabe, M. Yamamoto, and T. Toda. 2001. Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast. Dev. Cell 1:389-399.
17. Kitamura, K., and C. Shimoda. 1991. The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein. EMBO J. 10:3743-3751.
18. Kjaerulff, S., D. Dooijes, H. Clevers, and O. Nielsen. 1997. Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S. pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites. EMBO J. 16:4021-4033.
19. Kudo, N., B. Wolff, T. Sekimoto, E. P. Schreiner, Y. Yoneda, M. Yanagida, S. Horinouchi, and M. Yoshida. 1998. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp. Cell Res. 242:540-547.
20. + gene, which encodes a pivotal transcription factor for sexual development. Mol. Biol. Cell 11:3205-3217.
21. Li, B., W. Zhang, G. Chan, A. Jancso-Radek, S. Liu, and M. A. Weiss. 2001. Human sex reversal due to impaired nuclear localization of SRY. A clinical correlation. J. Biol. Chem. 276:46480-46484.
22. + kinase. Cell 87:869-880.
23. Lopez-Girona, A., B. Furnari, O. Mondesert, and P. Russell. 1999. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature 397:172-175.
24. Lopez-Girona, A., J. Kanoh, and P. Russell. 2001. Nuclear exclusion of Cdc25 is not required for the DNA damage checkpoint in fission yeast. Curr. Biol. 11:50-54.
25. Love, J. J., X. Li, D. A. Case, K. Giese, R. Grosschedl, and P. E. Wright. 1995. Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature 376:791-795.
26. + protein kinase regulates entry into meiosis in Schizosaccharomyces pombe. Nature 332:509-514.
27. + gene, expressed under control of the mating type locus, induces meiosis and sporulation in fission yeast. EMBO J. 6:729-736.
28. Nagai, K. 2001. Molecular evolution of Sry and Sox gene. Gene 270:161-169.
29. Nakielny, S., and G. Dreyfuss. 1999. Transport of proteins and RNAs in and out of the nucleus. Cell 99:677-690.
30. Nurse, P. 1985. Mutations of the fission yeast Schizosaccharomyces pombe which alter the shift between cell proliferation and sporulation. Mol. Gen. Genet. 198:497-502.
31. Okazaki, N., K. Okazaki, Y. Watanabe, M. Kato-Hayasbi, M. Yamamoto, and H. Okayama. 1998. Novel factor highly conserved among eukaryotes controls sexual development in fission yeast. Mol. Cell. Biol. 18:887-895.
32. Petersen, J., O. Nielsen, R. Egel, and I. M. Hagan. 1998. FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation. J. Cell Biol. 141:1217-1228.
33. Petersen, J., D. Weilguny, R. Egel, and O. Nielsen. 1995. Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation. Mol. Cell. Biol. 15:3697-3707.
34. a. Qin, J., Z. Peng, and M. McLeod. In vitro mutagenesis to define functional domains. Methods Mol. Biol., in press.
35. Rehberg, S., P. Lischka, G. Glaser, T. Stamminger, M. Wegner, and O. Rosorius. 2002. Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation. Mol. Cell. Biol. 22: 5826-5834.
36. Roose, J., and H. Clevers. 1999. TCF transcription factors: molecular switches in carcinogenesis. Biochim. Biophys. Acta 1424:M23-37.
37. Sato, M., Y. Watanabe, Y. Akiyoshi, and M. Yamamoto. 2002. 14-3-3 protein interferes with the binding of RNA to the phosphorylated form of fission yeast meiotic regulator mei2p. Curr. Biol. 12:141-145.
38. Shimoda, C., A. Hirata, M. Kishida, T. Hashida, and K. Tanaka. 1985. Characterization of meiosis-deficient mutants by electron microscopy and mapping of four essential genes in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 200:252-257.
39. Sipiczki, M. 1988. The role of sterility genes (ste and aff) in the initiation of sexual development in Schizosaccharomyces pombe. Mol. Gen. Genet. 213: 529-534.
40. Soullier, S., P. Jay, F. Poulat, J. M. Vanacker, P. Berta, and V. Laudet. 1999. Diversification pattern of the HMG and SOX family members during evolution. J. Mol. Evol. 48:517-527.
41. Stommel, J. M., N. D. Marchenko, G. S. Jimenez, U. M. Moll, T. J. Hope, and G. M. Wahl. 1999. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18:1660-1672.
42. + encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev. 5:1990-1999.
43. Travers, A. 2000. Recognition of distorted DNA structures by HMG domains. Curr. Opin. Struct. Biol. 10:102-109.
44. van de Wetering, M., and H. Clevers. 1992. Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix. EMBO J. 11:3039-3044.
45. Van Heeckeren, W. J., D. R. Dorris, and K. Struhl. 1998. The mating type proteins of fission yeast induce meiosis by directly activating mei3 transcription. Mol. Cell. Biol. 18:7317-7326.
46. Wang, W., P. Li, A. Schettino, Z. Peng, and M. McLeod. 1998. Characterization of functional regions in the Schizosaccharomyces pombe mei3 developmental activator. Genetics 150:1007-1018.
47. Watanabe, M., N. Masuyama, M. Fukuda, and E. Nishida. 2000. Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal. EMBO Rep. 1:176-182.
48. Watanabe, Y., S. Shinozaki-Yabana, Y. Chikashige, Y. Hiraoka, and M. Yamamoto. 1997. Phosphorylation of RNA-binding protein controls cell cycle switch from mitotic to meiotic in fission yeast. Nature 386:187-190.
49. + encodes an RNA-binding protein essential for premeiotic DNA synthesis and meiosis I, which cooperates with a novel RNA species, meiRNA. Cell 78:487-498.
50. Wegner, M. 1999. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res. 27:1409-1420.
51. Willer, M., L. Hoffmann, U. Styrkarsdottir, R. Egel, J. Davey, and O. Nielsen. 1995. Two-step activation of meiosis by the mat1 locus in Schizosaccharomyces pombe. Mol. Cell. Biol. 15:4964-4970.