Melatonin enhances cellular and humoral immune responses in the Japanese quail (Coturnix coturnix japonica) via an opiatergic mechanism

General and Comparative Endocrinology

Volumn 131, Issue 3, 2003, Pages 258-263

  Moore, C B ^a   Siopes, T D ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DILUENT; MELATONIN; NALTREXONE; OPIATE; PHYTOHEMAGGLUTININ; WATER;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BASOPHIL; CELL SUSPENSION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG EFFECT; ERYTHROCYTE; FEMALE; HUMORAL IMMUNITY; IMMUNOSTIMULATION; NONHUMAN; PRIORITY JOURNAL; QUAIL; SKIN ALLERGY;

EID: 0037404002     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/S0016-6480(03)00011-X     Document Type: Article

References (33)

1. Axelrod J., Fraschini F., Velo G.P. The pineal gland and its endocrine role. Proceedings of the NATO Advisory Study Institute, Erice, Italy. 1981;Plenum Press, New York.
2. Bonilla E., Rodon C., Valero N., Pons H., Chacin-Bonilla L., Garcia Tamayo J., Rodriguez Z., Medina-Leendertz S., Anez F. Melatonin prolongs survival of immunodepressed mice infected with the Venezuelan equine encephalomyelitis virus. Transactions of the Royal Society of Tropical Medicine and Hygiene. 95(2):2001;207-210.
3. Brennan C.P., Hendricks III G.L., El-Sheikh T.M., Mashaly M.M. Melatonin and the enhancement of immune responses in immature male chickens. Poultry Science. 81(3):2002;371-375.
4. Calvo J.R., Rafii-el-Idrissi M., Pozo D., Guerrero J.M. Immunomodulatory role of melatonin: specific binding sites in human and rodent lymphoid cells. Journal of Pineal Research. 18(3):1995;119-126.
5. Fischer E.G., Falke N.E. Beta-endorphin modulates immune functions. Psychotherapy and Psychosomatics. 42(1-4):1984;195-204.
6. Krieger D.T. Endocrine Rhythms. 1981;Raven press, New York.
7. Kumar M.S., Chen C.L., Sharp D.C., Liu J.M., Kalra P.S., Kalra S.P. Diurnal fluctuations in methionine-enkephalin levels in the hypothalamus and preoptic area of the male rat: effects of pinealectomy. Neuroendocrinology. 35(1):1982;28-34.
8. Lakin M.L., Miller C.H., Stott M.L., Winters W.D. Involvement of the pineal gland and melatonin in murine analgesia. Life Science. 19(24):1981;2543-2547.
9. 125I Iodomelatonin-binding sites in the bursa of Fabricius of birds: binding characteristics, subcellular distribution, diurnal variations and age studies. Journal of Endocrinology. 138(1):1993;51-57.
10. Maestroni G.J. The immunotherapeutic potential of melatonin. Expert Opinon on Investigational Drugs. 10(3):2001;467-476.
11. Maestroni G.J., Conti A., Pierpaoli W. Role of the pineal gland in immunity: circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. Journal of Neuroimmunology. 13(1):1986;19-30.
12. Maestroni G.J.M., Conti A. β-Endorphin and dynorphin mimic the circadian immunoenhancing and anti-stress effects of melatonin. International Journal of Immunopharmacology. 11(4):1989;333-340.
13. Maestroni G.J.M., Conti A. The pineal neurohormone melatonin stimulates activated CD4+, Thy-1+ cells to release opioid agonist(s) with immunoenhancing and anti-stress properties. Journal of Neuroimmunology. 28(2):1990;167-176.
14. Maestroni G.J.M., Conti A., Pierpaoli W. Role of the pineal gland in immunity. II. Melatonin enhances the antibody response via an opiatergic mechanism. Clinical and Experimental Immunology. 68(2):1987;384-391.
15. Maestroni G.J.M., Conti A., Pierpaoli W. Pineal melatonin, its fundamental immunoregulatory role in aging and cancer. Annals New York Academy of Science. 521:1988;140-148.
16. Maestroni G.J.M., Conti A., Pierpaoli W. Role of the pineal gland in immunity. III. Melatonin antagonizes the immunosuppressive effect of acute stress via an opiatergic mechanism. Immunology. 63(3):1988;465-469.
17. Maestroni G.J.M., Conti A., Pierpaoli W. Melatonin, stress, and the immune system. Reiter R.J. Pineal Research Reviews. vol. 7:1989;203-223 Alan R. Liss, New York.
18. Maestroni G.J.M., Conti A., Pierpaoli W. The pineal gland and the circadian opiatergic immunoregulatory role of melatonin. Annals New York Academy of Science. 496:1987;67-77.
19. Moore C.B., Siopes T.D. Effects of lighting conditions and melatonin supplementation on the cellular and humoral immune responses in Japanese quail Coturnix coturnix japonica. General and Comparative Endocrinology. 119(1):2000;95-104.
20. Moore C.B., Siopes T.D. Melatonin can produce immunoenhancement in Japanese quail (Coturnix coturnix japonica) without prior immunosuppression. General and Comparative Endocrinology. 129:2002;122-126.
21. Moore C.B., Siopes T.D., Steele C.T., Underwood H. Pineal melatonin secretion, but not ocular melatonin secretion, is sufficient to maintain normal immune responses in Japanese quail (Coturnix coturnix japonica). General and Comparative Endocrinology. 126(3):2002;352-358.
22. Nelson C.J., Carrigan K.A., Lysle D.T. Naltrexone administration attenuates surgery-induced immune alterations in rats. Journal of Surgical Research. 94(2):2000;172-177.
23. Nelson R.J., Demas G.E. Seasonal changes in immune function. Quarterly Review of Biology. 71(4):1996;511-548.
24. Nelson R.J., Drazen D.L. Melatonin mediates seasonal adjustments in immune function. Reproduction, Nutrition, Development. 39(3):1999;383-398.
25. Plotnikoff N.P., Faith R., Murgo A.J., Good R. Enkephalins and Endorphins: Stress and the Immune System. 1986;Plenum Press, New York.
26. Poon A.M., Liu Z.M., Pang C.S., Brown G.M., Pang S.F. Evidence for a direct action of melatonin on the immune system. Biological Signals. 3(2):1994;107-117.
27. Reiter R.J. The Pineal Gland. 1984;Raven Press, New York.
28. Rodriguez A.B., Lea R.W. Effect of pinealectomy upon the nonspecific immune response of the ring-dove Streptopelia risoria. Journal of Pineal Research. 16(3):1994;159-166.
29. SAS Institute, 1990. SAS/STAT® User's Guide. Version 6, fourth ed., vol. 2, SAS Institute Inc., Cary, NC.
30. Sever J.L. Application of a microtechnique to viral serological investigations. Journal of Immunology. 88(3):1962;320-329.
31. Sibinga N.E., Goldstein A. Opioid peptides and opioid receptors in cells of the immune system. Annual Review of Immunology. 6:1988;219-249.
32. Stadecker M.J., Lukic M., Dvorak A., Leskowitz S. The cutaneous basophil response to phytohemagglutinin in chickens. Journal of Immunology. 118(5):1977;1564-1568.
33. Weber R.S., Pert C.B. Opiatergic modulation of the immune system. Miller E.E., Genazzani A.R. Central and Peripheral Endorphins: Basic and Clinical Aspects. 1984;35 Raven Press, New York.