Myeloperoxidase has directly-opposed effects on nitration reaction - Study on myeloperoxidase-deficient patient and myeloperoxidase-knockout mice

Free Radical Research

Volumn 37, Issue 5, 2003, Pages 481-489

  Ichimori, Kohji ^a   Fukuyama, Naoto ^a   Nakazawa, Hiroe ^a   Aratani, Yasuaki ^b   Koyama, Hideki ^b   Takizawa, Shunya ^a   Kameoka, Yosuke ^c   Ishida Okawara, Akiko ^c   Kohi, Fumikazu ^d   Suzuki, Kazuo ^c  

^a TOKAI UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d Takamatsu National Hospital   (Japan)

Author keywords

Alanine aminotransferase; MPO; Neutrophil; Nitric oxide; Nitrotyrosine; Peroxynitrite

Indexed keywords

3 NITROTYROSINE; GLUTATHIONE; MYELOPEROXIDASE; NITRATE; NITRIC OXIDE; NITRITE; PHENOL; SCAVENGER;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOACCUMULATION; BIOSYNTHESIS; CASE REPORT; CATALYST; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME MECHANISM; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; KNOCKOUT MOUSE; LEUKOCYTE; LIVER ISCHEMIA; MALE; MOUSE; NITRATION; NITROGEN METABOLISM; NONHUMAN; REPERFUSION INJURY; REVIEW;

ADULT; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYDROGEN PEROXIDE; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRATES; NITRITES; NITROGEN DIOXIDE; NITROSATION; OXIDATION-REDUCTION; PEROXIDASE; REACTIVE NITROGEN SPECIES; TIME FACTORS; TYROSINE;

ANIMALIA;

EID: 0037402884     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/1071576031000099830     Document Type: Review

References (58)

1. Klebanoff, S.J. and Coombs, R.W. (1992) "Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system", J. Clin. Investig. 89, 2014-2017.
2. Kettle, A.J. and Winterbourn, C.C. (1997) "Myeloperoxidase: A key regulator of neutrophil oxidant production", Redox Rep. 3, 3-15.
3. Hampton, M.B., Kettle, A.J. and Winterbourn, C.C. (1996) "Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils", Infect. Immun. 64, 3512-3517.
4. Hampton, M.B., Kettle, A.J. and Winterbourn, C.C. (1998) "Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing", Blood 92, 3007-3017.
5. Furtmuller, P.G., Obinger, C., Hsuanyu, Y. and Dunford, H.B. (2000) "Mechanism of reaction of myeloperoxidase with hydrogen peroxide and chloride ion", Eur. J. Biochem. 267, 5858-5864.
6. Burner, U., Furtmuller, P.G., Kettle, A.J., Koppenol, W.H. and Obinger, C. (2000) "Mechanism of reaction of myeloperoxidase and nitrite", J. Biol. Chem. 275, 20597-20601.
7. Beckman, J.S., Ischiropoulos, H., Zhu, L., van der Woerd, M., Smith, C., Chen, J., Harrison, J., Martin, J.C. and Tsai, M. (1992) "Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite", Arch. Biochem. Biophys. 298, 438-445.
8. Ischiropoulos, H., Zhu, L., Chen, J., Tsai, M., Martin, J.C., Smith, C.D. and Beckman, J.S. (1992) "Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase", Arch. Biochem. Biophys. 298, 431-437.
9. Beckman, J.S., Ye, Y.Z., Anderson, P.G., Chen, J., Accavitti, M.A., Tarpey, M.M. and White, C.R. (1994) "Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry", Biol. Chem. Hoppe-Seyler 375, 81-88.
10. Kooy, N.W., Royall, J.A., Ye, Y.Z., Kelly, D.R. and Beckman, J.S. (1995) "Evidence for in vivo peroxynitrite production in human acute lung injury", Am. J. Respir. Crit. Care Med. 151, 1250-1254.
11. Kaur, H. and Halliwell, B. (1994) "Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients", FEBS Lett. 350, 9-12.
12. Takizawa, S., Fukuyama, N., Hirabayasshi, H., Nakazawa, H. and Shinohara, Y. (1999) "Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia", J. Cereb. Blood Flow Metab. 19, 667-672.
13. Tsuji, C., Shioya, S., Hirota, Y., Fukuyama, N., Kurita, D., Tanigaki, T., Ohta, Y. and Nakazawa, H. (2000) "Increased production of nitrotyrosine in lung tissue of rats with radiation-induced acute lung injury", Am. J. Physiol. 278, L719-L725.
14. Ferdinandy, P., Danial, H., Ambrus, I., Rothery, R.A. and Schulz, R. (2000) "Peroxynitrite is a major contributor to cytokine-induced myocardinal contractile failure", Circ. Res. 87, 241-247.
15. Radi, R., Peluffo, G., Alvarez, M.N., Naviliat, M. and Cayota, A. (2001) "Unraveling peroxynitrite formation in biological systems", Free Radic. Biol. Med. 30, 463-488.
16. Jacob, J.S., Cistol, D.P., Hsu, F.F., Muzaffar, S., Mueller, D.M., Hazen, S.L. and Heinecke, J.W. (1996) "Human phagocytes employ the myeloperoxidase-hydrogen peroxide system to synthesize dityrosine, trityrosine, pulcherosine, and isodityrosine by a tyrosyl radical-dependent pathway", J. Biol. Chem. 271, 19950-19956.
17. Daugherty, A., Dunn, J.L., Rateri, D.L. and Heinecke, J.W. (1994) "Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions", J. Clin. Investig. 94, 437-444.
18. Hazen, S.L. and Heinecke, J.W. (1997) "3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima", J. Clin. Investig. 99, 2075-2081.
19. Heinecke, J.W. (1998) "Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis", Atherosclerosis 141, 1-15.
20. Hazen, S.L., Zhang, R., Shen, Z., Wu, W., Podrez, E.A., MacPherson, J.C., Schmitt, D., Mitra, S.N., Mukhopadhyay, C., Chen, Y., Cohen, P.A., Hoff, H.F. and Abu-Soud, H.M. (1999) "Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes: pathways for monocyte-mediated protein nitration and lipid peroxidation in vivo", Circ. Res. 85, 950-958.
21. Eiserich, J.P., Hristova, M., Cross, C.E., Jones, A.D., Freeman, B.A., Halliwell, B. and van der Vliet, A. (1998) "Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils", Nature 391, 393-397.
22. Fukuyama, N., Ichimori, K., Su, Z., Ishida, H. and Nakazawa, H. (1996) "Peroxynitrite formation from activated human leukocytes", Biochem. Biophys. Res. Commun. 224, 414-419.
23. Schmidt, H.H., Seifert, R. and Bohme, E. (1989) "Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4", FEBS Lett. 244, 357-360.
24. Riesco, A., Caramelo, C., Blum, G., Monton, M., Gallego, M.J., Casado, S. and Lopez-Farre, A. (1993) "Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes", Biochem. J. 292, 791-796.
25. Carreras, M.C., Pargament, G.A., Catz, S.D., Poderoso, J.J. and Boveris, A. (1994) "Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils", FEBS Lett. 341, 65-68.
26. Wallerath, T., Gath, I., Aulitzky, W.E., Pollock, J.S., Kleinert, H. and Forstermann, U. (1997) "Identification of the NO synthase isoforms expressed in human neutrophil granulocytes, megakaryocytes and platelets", Thromb. Haemostasis 77, 163-167.
27. Eiserich, J.P., Cross, C.E., Jones, A.D., Halliwell, B. and van der Vliet, A. (1996) "Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid. A novel mechanism for nitric oxide-mediated protein modification", J. Biol. Chem. 271, 19199-19208.
28. Panasenko, O.M., Briviba, K., Klotz, L.O. and Sies, H. (1997) "Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous, acid with nitrite", Arch. Biochem. Biophys. 343, 254-259.
29. van der Vliet, A., Eiserich, J.P., Halliwell, B. and Cross, C.E. (1997) "Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide- dependent toxicity", J. Biol. Chem. 272, 7617-7625.
30. , Biochemistry 39, 4640-4648.
31. Cassina, A.M., Hodara, R., Souza, J.M., Thomson, L., Castro, L., Ischiropoulos, H., Freeman, B.A. and Radi, R. (2000) "Cytochrome c nitration by peroxynitrite", J. Biol. Chem. 275, 21409-21415.
32. MacMillan-Crow, L.A., Greendorfer, J.S., Vickers, S.M. and Thompson, J.A. (2000) "Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma", Arch. Biochem. Biophys. 377, 350-356.
33. Eiserich, J.P., Estevez, A.G., Bamberg, T.V., Ye, Y.Z., Chumley, P.H., Beckman, J.S. and Freeman, B.A. (1999) "Microtubule dysfunction by posttranslational nitrotyrosination of alphatubulin: a nitric oxide-dependent mechanism of cellular injury", Proc. Natl Acad. Sci. USA 96, 6365-6370.
34. Mihm, M.J., Jing, L. and Bauer, J.A. (2000) "Nitrotyrosine causes selective vascular endothelial dysfunction and DNA damage", J. Cardiovasc. Pharmacol. 36, 182-187.
35. Suzuki, K., Nunoi, H., Miyazaki, M. and Koi, F. (2000) "Prevalence of inherited myeloperoxidase deficiency in Japan", In: Petrides, P.E. and Nauseef, W.M., eds, The Peroxidase Multigene Family of Enzymes (Springer, Berlin), pp. 560-571.
36. Suzuki, K., Ota, H., Sasagawa, S., Sakatani, T. and Fujikura, T. (1983) "Assay method for myeloperoxidase in human polymorphonuclear leukocytes", Anal. Biochem. 132, 345-352.
37. McCord, J.M. and Fridovich, I. (1969) "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)", J. Biol. Chem. 244, 6049-6055.
38. Green, L.C., Wagner, D.A., Glogowski, J., Skipper, P.L., Wishnok, J.S. and Tannenbaum, S.R. (1982) "Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids", Anal. Biochem. 126, 131-138.
39. Ischiropoulos, H., Zhu, L. and Beckman, J.S. (1992) "Peroxynitrite formation from macrophage-derived nitric oxide", Arch. Biochem. Biophys. 298, 446-451.
40. Sampson, J.B., Rosen, H. and Beckman, J.S. (1996) "Peroxy-nitrite-dependent tyrosine nitration catalyzed by superoxide dismutase, myeloperoxidase, and horseradish peroxidase", Methods Enzymol. 269, 210-218.
41. Beckman, J.S., Beckman, T.W, Chen, J., Marshall, P.A. and Freeman, B.A. (1990) "Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide", Proc. Natl Acad. Sci. USA 87, 1620-1624.
42. Sawa, T., Akaike, T. and Maeda, H. (2000) "Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase", J. Biol. Chem. 275, 32467-32474.
43. Halejcio-Delophont, P., Hoshiai, K., Fukuyama, N. and Nakazawa, H. (2001) "No evidence of NO-induced damage in potential donor organs after brain death", J. Heart Lung Transplant. 20, 71-79.
44. Aratani, Y., Koyama, H., Nyui, S., Suzuki, K., Kura, F. and Maeda, N. (1999) "Severe impairment in early host defense against Candida albicans in mice deficient myeloperoxidase", Infect. Immun. 67, 1828-1836.
45. Khan, J., Brennand, D.M., Bradley, N., Gao, B., Bruckdorfer, R., Jacobs, M. and Brennan, D.M. (1998) "3-Nitrotyrosine in the proteins of human plasma determined by an ELISA method", Biochem. J. 330, 795-801.
46. Sokolovsky, M., Riordan, J.F. and Vallee, B.L. (1966) "Tetranitromethane. A reagent for the nitration of tyrosyl residues in proteins", Biochemistry 5, 3582-3589.
47. Goldstein, S., Czapski, G., Lind, J. and Merenyi, G. (2000) "Tyrosine nitration by simultaneous generation of (.)NO and O-(2) under physiological conditions. How the radicals do the job", J. Biol. Chem. 275, 3031-3036.
48. Sampson, J.B., Ye, Y., Rosen, H. and Beckman, J.S. (1998) "Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide", Arch. Biochem. Biophys. 356, 207-213.
49. Wu, W., Chen, Y. and Hazen, S.L. (1999) "Eosinophil peroxidase nitrates protein yrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders", J. Biol. Chem. 274, 25933-25944.
50. Abu-Soud, H.M. and Hazen, S.L. (2000) "Nitric oxide modulates the catalytic activity of myeloperoxidase", J. Biol. Chem. 275, 5425-5430.
51. Huie, R.E. and Padmaja, S. (1993) "The reaction of NO with superoxide", Free Radic. Res. Commun. 18, 195-199.
52. Balabanli, B., Kamisaki, Y., Martin, E. and Murad, F. (1999) "Requirements for heme and thiols for the nonenzymatic modification of nitrotyrosine", Proc. Natl Acad. Sci. USA 96, 13136-13141.
53. Jiang, Q. and Hurst, J.K. (1997) "Relative chlorinating, nitrating, and oxidizing capabilities of neutrophils determined with phagocytosable probes", J. Biol. Chem. 272, 32767-32772.
54. Kaur, H., Lyras, L., Jenner, P. and Halliwell, B. (1998) "Artefacts in HPLC detection of 3-nitrotyrosine in human brain tissue", J. Neurochem. 70, 2220-2223.
55. Crow, J.P. (1999) "Measurement and significance of free and protein-bound 3-nitrotyrosine, 3-chlorotyrosine, and free 3-nitro-4-hydroxyphenylacetic acid in biologic samples: a high-performance liquid chromatography method using electrochemical detection", Methods Enzymol. 301, 151-160.
56. Tan, S., Bose, R. and Derrick, M. (2001) "Hypoxia-ischemia in fetal rabbit brain increases reactive nitrogen species production: quantitative estimation of nitrotyrosine", Free Radic. Biol. Med. 30, 1045-1051.
57. van der Vliet, A., Nguyen, M.N., Shigenaga, M.K., Eiserich, J.P., Marelich, G.P. and Cross, C.E. (2000) "Myeloperoxidase and protein oxidation in cystic fibrosis", Am. J. Physiol. Lung Cell. Mol. Physiol. 279, L537-L546.
58. Brennan, M.L., Anderson, M.M., Shih, D.M., Qu, X.D., Wang, X., Mehta, A.C., Lim, L.L., Shi, W., Hazen, S.L., Jacob, J.S., Crowley, J.R., Heinecke, J.W. and Lusis, A.J. (2001) "Increased atherosclerosis in myeloperoxidase-deficient mice", J. Clin.