[3H]-ketanserin binding sites in different psychiatric disorders

Neurochemistry International

Volumn 42, Issue 6, 2003, Pages 511-516

  Marazziti, Donatella ^a   Giannaccini, Gino ^a   Giromella, Annalisa ^a   Betti, Laura ^a   Pesce, Debora ^a   Nardi, Irma ^a   Rossi, Alessandra ^a   Lucacchini, Antonio ^a   Cassano, Giovanni Battista ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Human brain postmortem; Psychiatric disorders; Serotonin; Serotonin receptors of type 2a; Tritiated ketanserin in binding sites

Indexed keywords

KETANSERIN; SEROTONIN 2A RECEPTOR; SEROTONIN ANTAGONIST; TRITIUM;

ADULT; ARTICLE; BINDING AFFINITY; BINDING SITE; BIPOLAR DISORDER; BRAIN; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; FRONTAL CORTEX; HEMISPHERE; HUMAN; HUMAN TISSUE; MALE; MENTAL DISEASE; PARIETAL LOBE; PRIORITY JOURNAL; SCHIZOPHRENIA; METABOLISM;

BINDING SITES; HUMANS; KETANSERIN; MENTAL DISORDERS; SEROTONIN ANTAGONISTS; TRITIUM;

EID: 0037401682     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(02)00093-1     Document Type: Article

References (32)

1. American Psychiatric Association (APA), 1994. Diagnostic and Statistical Manual for Mental Disorders, 4th ed., American Psychiatric Press, Washington, DC, USA.
2. 2 and beta-adrenergic receptor binding sites in the brain of suicide victims. Arch. Gen. Psychiat. 47:1990;1038-1047.
3. Arato M., Frecska E., Tekes K., MacCrimmon D.J. Serotonergic interhemispheric asymmetry: gender difference in the orbital cortex. Acta Psychiat. Scand. 84(1):1991;110-111.
4. 18F ]-spiperone during depressive illness and antidepressant treatment with clomipramine Biol. Psychiat. 45:1999;180-186.
5. 2A receptor binding index in deliberate self-harm patients. Eur. J. Nucl. Med. 28(2):2001;175-182.
6. 2 receptor binding on platelets of delinquent adolescents. Psychopharmacology. 118:1995;354-356.
7. 2A receptor mRNA in human brain. Brain Res. 676(1):1995;157-168.
8. Crow T.J., Cross A.J., Cooper S.J., Deakin J.F., Ferrier I.N., Johnson J.A., Joseph M.H., Owen F., Poulter M., Lofthouse R. Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides. Neuropharmacology. 12B:1984;1561-1569.
9. Dean B. A predicted cortical serotonergic/cholinergic/GABAergic interface as a site of pathology in schizophrenia. Clin. Exp. Pharmacol. Physiol. 28(1/2):1991;74-78.
10. Gerlach J. New antipsychotics: classification, efficacy and adverse effects. Schizophr. Bull. 155(Suppl. 5):1991;33-36.
11. 2 agonist or antagonist? Neuropsychopharmacology. 118:1990;354-356.
12. Gurevich E.V., Joyce J.N. Alterations in the cortical serotonergic system in schizophrenia: a postmortem study. Biol. Psychiat. 42(7):1997;529-545.
13. 11C ]-M100907 Synapse. 38(4):2000;421-431.
14. 2A receptor binding in patients with chronic schizophrenia. Psychopharmacology. 112:1993;S35-S39.
15. Heninger, G.R., 1991. The role of serotonin in clinical disorders. In: Bloom, F.E., Meltzer, H.Y. (Eds.), Psychopharmacology: The Fourth Generation of Progress. Raven Press, New York, pp. 471-482.
16. 2 sites in cortex and amygdala. Brain Res. 614(1/2):1993;37-44.
17. Joyce N.J., Shane A., Lexow N., Winokur A., Casanova M., Kleinman J.E. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology (Berl.). 124(1/2):1993;95-106.
18. 2 receptor binding sites Mol. Pharmacol. 21:1982;301-314.
19. Lovenberg T.W., Erlander M.G., Baron B.M., Sutcliffe J.G. Cloning of new 5-HT receptors. Int. Clin. Psychopharmacol. 8(S2):1993;19-23.
20. 3H ]-ketanserin binding in human brain postmortem Neurochem. Res. 22(6):1997;753-757.
21. Martin G.R., Humphrey P.P.A. Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature. Neuropharmacology. 33:1994;261-273.
22. McPherson, G.A., 1985. KINETIC, EBDA, LIGAND, LOWRY: a Collection of Ratio Ligand Binding Analysis Programs. Biosoft, Cambridge, UK.
23. 2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites. Brain Res. 524:1990;139-143.
24. Pasqualetti M., Nardi I., Ladinsky H., Marazziti D., Cassano G.B. Comparative anatomical distribution of serotonin 1A, 1D alpha and 2A receptor mRNAs in human brain postmortem. Brain Res. Mol. Brain Res. 39(1/2):1996;223-233.
25. Pazos A., Probst A., Palacios J.M. Serotonin receptors in human brain. I. Autoradiographic mapping of serotonin-2 receptors. Neuroscience. 21:1987;123-139.
26. Peterson G.L. A simplification of the protein assay method which is more generally applicable. Anal. Biochem. 83:1977;356-366.
27. 3H ]-paroxetine binding sites in suicide brains Psychiat. Res. 82(3):1998;161-170.
28. 1C receptors. J. Pharmacol. Exp. Ther. 260:1992;1361-1365.
29. Srinivas E.F., Sublash M.N., Vinod K.Y. Cortical 5-HT1A receptor downregulation by antidepressants in the rat brain. Neurochem. Int. 438:2001;573-579.
30. Torrey E.F., Webster M., Knable M., Johnston N., Yolken R.H. The Stanley Foundation brain collection and neuropathology consortium. Schizophr. Res. 44:2000;151-155.
31. 2 receptor changes in major depression. Biol. Psychiat. 27(5):1990;489-496.
32. Zifa E., Fillion G. 5-Hydroxytryptamine receptors. Pharmacol. Rev. 44(3):1994;402-457.