Investigating genotoxic and hematotoxic effects of N-nitrosodimethylamine, N-nitrosodiethylamine and N-nitrosodiethanolamine in the hen's egg-micronucleus test (HET-MN)

Food and Chemical Toxicology

Volumn 41, Issue 4, 2003, Pages 561-573

  Wolf, Th ^a   Niehaus Rolf, C ^a   Luepke, N P ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

Alternatives to animal testing; Chick embryo; Genotoxicity; Hematotoxicity; Hen's eggs; In ovo; In vitro; Micronucleus test; Mutagenicity; NDMA, NDEA, NDELA

Indexed keywords

BIS(2 HYDROXYETHYL)NITROSAMINE; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE;

ANEMIA; ARTICLE; BLOOD SAMPLING; BLOOD TOXICITY; CONTROLLED STUDY; DOSE RESPONSE; EGG; ERYTHROCYTE; GENOTOXICITY; HEN; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; RELIABILITY; REPRODUCIBILITY; TOXICITY TESTING;

ANIMALS; CHICK EMBRYO; CHICKENS; CYCLOPHOSPHAMIDE; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE COUNT; FEMALE; HEMATOLOGIC DISEASES; MICRONUCLEUS TESTS; MUTAGENS;

ANIMALIA; RODENTIA;

EID: 0037399937     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(02)00281-8     Document Type: Article

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