Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan

Hepatology Research

Volumn 25, Issue 4, 2003, Pages 371-376

  Moriya, Kyoji ^a,b   Shintani, Yoshizumi ^a   Fujie, Hajime ^b   Miyoshi, Hideyuki ^b   Tsutsumi, Takeya ^a   Yotsuyanagi, Hiroshi ^a   Iino, Shiro ^a   Kimura, Satoshi ^a   Koike, Kazuhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apolipoprotein; Hypocholesterolemia; Steatosis

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN B; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; BODY MASS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EUROPE; FATTY LIVER; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HYPOBETALIPOPROTEINEMIA; HYPOCHOLESTEROLEMIA; JAPAN; LIPID BLOOD LEVEL; LIPID METABOLISM; LIVER DISEASE; MALE; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS;

EID: 0037398942     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6346(02)00309-1     Document Type: Article

References (27)

1. Saito I, Miyamura T, Ohbayashi A, et al. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci USA 1990;87:6547-9.
2. Simonetti RG, Camma C, Fiorello F, et al. Hepatitis C virus infection as a risk factor for hepatocellular carcinoma in patients with cirrhosis. Ann Intern Med 1992;116:97-102.
3. Bach N, Thung SN, Schaffner F. The histological features of chronic hepatitis C and autoimmume chronic hepatitis: a comparative analysis. Hepatology 1992;15:572-7.
4. Lefkowitch JH, Schiff ER, Davis GL, et al. Pathological diagnosis of chronic hepatitis C: a multicenter comparative study with chronic hepatitis B. Gastroenterology 1993;104:595-603.
5. Scheuer PJ, Ashrafzadeh P, Sherlock S, Brown D, Dusheiko GM. The pathology of chronic hepatitis C. Hepatology 1992;15:567-71.
6. Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX. Hepatitis C virus and other flaviviridae viruses enter cells via low-density lipoprotein receptor. Proc Natl Acad Sci USA 1996;96:12766-71.
7. Monazahian M, Bohme I, Bonk S, et al. Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J Med Virol 1999;57:223-9.
8. Barba G, Harper F, Harada T, et al. Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplet. Proc Natl Acad Sci USA 1997;94:1200-5.
9. Sabile A, Perlemuter G, Bono F, et al. Hepatitis C virus core protein binds to apolipoprotein AII and its secretion is modulated by fibrates. Hepatology 1999;30:1064-76.
10. Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, et al. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 1997;78:1527-31.
11. Lerat H, Honda M, Beard MR, et al. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology 2002;122:352-65.
12. Moriya K, Todoroki T, Tsutsumi T, et al. Increase of carbon 18 mono-unsaturated fatty acids in the liver of hepatitis C: Analysis in transgenic mice and humans. Biophys Biochem Res Commun 2001;281:1207-12.
13. Moriya K, Fujie H, Shintani Y, et al. Hepatitis C virus core protein induces hepatocellular carcinoma in transgenic mice. Nature Med 1998;4:1065-8.
14. Pawlotsky JM, Tsakiris L, Roudot-Thoraval F, et al. Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C. J Infect Dis 1999;171:1607-10.
15. Rubbia-Brandt L, Quadri R, Abid K, et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 2000;33:106-15.
16. Mihm S, Fayyazi A, Hartmann H, Ramadori G. Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype. Hepatology 1997;25:735-9.
17. Serfaty L, Andreani T, Giral P, Carbonell N, Chazouilleres O, Poupon R. Hepatitis C virus induced hypobeta-lipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C. J Hepatol 2001;34:428-34.
18. Fujie H, Yotsuyanagi H, Moriya K, et al. Steatosis and intrahepatic hepatitis C virus in chronic hepatitis. J Med Virol 1999;59:141-5.
19. Haruna Y, Miyamoto T, Yasunami R, Kanda T, Fushimi H, Kotoh K. Human leukocyte antigen DRB1 1302 protects against bile duct damage and portal lymphocyte infiltration in patients with chronic hepatitis C. J Hepatol 2000;32:837-42.
20. Yotsuyanagi H, Koike K, Yasuda K, et al. Hepatitis C virus genotypes and development of hepatocellular carcinoma. Cancer 1995;76:1352-5.
21. Okamoto H, Mishiro S. Genetic heterogeneity of hepatitis C virus. Intervirology 1994;37:68-76.
22. Ohno O, Mizokami M, Wu RR, et al. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J Clin Microbiol 1997;35:201-7.
23. Perlemuter G, Sabile A, Letteron P, et al. Hepatitis C virus core protein inhibits triglyceride-transfer protein activity and very low-density lipoprotein secretion: a model of viral-related steatosis. FASEB J 2002;16:185-94.
24. Vu-Dac N, Schoonjans K, Laine B, Fruchart JC, Auwerx J, Staels B. Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J Biol Chem 1994;269:31012-8.
25. Vu-Dac N, Schoonjans K, Kosykh V, et al. Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J Clin Invest 1995;96:741-50.
26. Enomoto N, Sakuma I, Asahina Y, et al. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. New Eng J Med 1996;334:77-81.
27. Brechot C. The direct interplay between HCV NS5A protein and interferon transduction signal: from clinical to basic science. J Hepatol 1999;30:1152-4.