In vivo studies of altered expression patterns of p55 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis

European Journal of Biochemistry

Volumn 270, Issue 7, 2003, Pages 1493-1501

  Borrás, Elisa ^a   Zaragozá, Rosa ^a   Morante, María ^a   García, Concha ^a   Gimeno, Amparo ^a   López Rodas, Gerardo ^a   Barber, Teresa ^a   Miralles, Vicente J ^a   Viña, Juan R ^a,b   Torres, Luis ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

c Jun; Cyclin D1; p53; Retinoic acid; Vitamin A

Indexed keywords

CYCLIN D1; CYTOCHROME C; DNA FRAGMENT; PROTEIN P21; PROTEIN P53; RAS PROTEIN; RETINOIC ACID RECEPTOR; RETINOL PALMITATE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DISPLAY; DRUG EFFECT; GENE CONTROL; GENE EXPRESSION; HYPERVITAMINOSIS; IMMUNOPRECIPITATION; IN VIVO STUDY; LIVER CELL; LUNG; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; RAT; RECEPTOR BINDING; RETINOL DEFICIENCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITAMIN SUPPLEMENTATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CHRONIC DISEASE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYPERVITAMINOSIS A; LIVER; LUNG; MACROMOLECULAR SUBSTANCES; PRECIPITIN TESTS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, WISTAR; RECEPTORS, RETINOIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN A; VITAMIN A DEFICIENCY;

ANIMALIA; CATOPTROPHORUS SEMIPALMATUS; CULLEN;

EID: 0037394161     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03511.x     Document Type: Article

References (42)

1. Chambon, P. (1996) A decade of molecular biology of retinoic acid receptors. FASEB J. 10, 940-954.
2. Evans, T.R.J. & Kayne, S.B. (1999) Retinoids; present role and future potential. Br. J. Cancer 80, 1-8.
3. Chen, Y., Derguini, F. & Buck, J. (1997) Vitamin A in serum is a survival factor for fibroblasts. Proc. Natl. Acad. Sci. 94, 10205-10208.
4. Mason, K.E. (1935) Foetal death, prolonged gestation and difficult parturition in the rat as a result of vitamin A deficiency. Am. J. Anat. 57, 303-349.
5. Hale, F. (1937) The relation of maternal vitamin A deficiency to microphthalmia in pigs. Texas State J. Med. 33, 228-232.
6. Zile, M.H. (2001) Function of vitamin A in vertebrate embryonic development. J. Nutr. 131, 705-708.
7. Niederreither, K., Subbarayan, V., Dollé, P. & Chambon, P. (1999) Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nature Genet. 21, 444-448.
8. Batourina, E., Gim, S., Bello, N., Shy, M., Clagett-Dame, M., Srinivas, S., Costantini, F. & Mendelsohn, C. (2001) Vitamin A controls epithelium/mesenchymal interactions through Ret expresion. Nature Genet. 27, 74-78.
9. Page, K.C., Heitzman, D.A. & Chernin, M.I. (1996) Stimulation of c-jun and c-myb in rat Sertoli cells following exposure to retinoids. Biochem. Biophys. Res. Comm. 225, 595-600.
10. Monagham, B.R. & Schmitt, F.O. (1932) The effects of carotene and of vitamin A on the oxidation of linoleic acid. J. Biol. Chem. 96, 387-395.
11. Ciaccio, M., Valenza, M., Tesoriere, L., Bongiorno, A., Albiero, R. & Livrea, M.A. (1993) Vitamin A inhibits doxorubicin-induced membrane lipid peroxidation in rat tissues in vivo. Arch. Biochem. Biophys. 90, 103-108.
12. Palacios, A., Piergiacomi, V.A. & Catalá, A. (1996) Vitamin A supplementation inhibits chemiluminescence and lipid peroxidation in isolated rat liver micrososmes and mitochondria. Mol. Cell Biochem. 154, 77-82.
13. Barber, T., Borrás, E., Torres, L., García, C., Cabezuelo, F., Lloret, A., Pallardó, F.V. & Viña, J.R. (2000) Vitamin A deficiency causes oxidative damage to liver mitochondria in rats. Free Rad. Biol. Med. 29, 1-7.
14. Murata, M. & Kawanishi, S. (2000) Oxidative DNA damage by vitamin A and its derivate via superoxide generation. J. Biol. Chem. 275, 2003-2008.
15. Siaems, W., Sommerburg, O., Schild, L., Augustin, W., Langhans, C.D. & Wiswedel, I. (2002) β-Carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration. FASEB J. 16, 1289-1291.
16. Barua, A.B. & Olson, J.A. (1998) Reversed-phase gradient high performance liquid chromatographic procedure for simultaneous analysis of very polar to non-polar retinoids, carotenoids and tocopherols in animals and plant samples. J. Chromatogr. B. 707, 69-79.
17. Otero, G., Avila, M.A., De la Peña, L., Emfietzoglou, J., Cansado, G.F. & Popescu, and Notario, V. (1997) Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochorme c oxidase in syrian hamster fetal cells initiated with ionizing radiation. Carcinogenesis 18, 1569-1775.
18. Liang, P. & Pardee, A.B. (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-971.
19. Hamon, G.H. & Cameron, G.N. (1986) The EMBL data library. Nucleic Acids Res. 14, 5-10.
20. Bilofsky, H.S., Burks, C. & The GenBank data bank. (1988) Nucl Acids Res. 16, 1861-1864.
21. Pearson, W.R. & Lipmann, D.J. (1988) Improved tools for biological sequences comparison. Procl. Natl. Acad. Sci. USA 85, 2444-2448.
22. Chomczynski, P. & Sacchi, N. (1987) Single-step method for RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
23. Thomas, P.S. (1980) Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 162, 156-159.
24. Romero, F.J. & Viña, J. (1983) A simple procedure for the preparation of isolated liver cells. Biochem. Educ. 11, 135-136.
25. Schreiber, M., Kolbus, A., Piu, F., Szabowski, A., Möhle-Steinlein, U., Tian, J., Karin, M., Angel, P. & Wagner, E.F. (1999) Control of cell cycle progression by c-jun is p53 dependent. Genes Dev. 13, 607-619.
26. Wisdom, R., Johnson, R.S. & Moore, C. (1999) c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18, 188-197.
27. Griffiths, J.K. (2000) The vitamin A paradox. J. Pediatr. 137, 604-607.
28. Mechta-Grigoriou, F., Gerald, D. & Yaniv, M. (2001) The mammalian Jun proteins: redundancy and specificity. Oncogene 20, 2378-2389.
29. Peto, R., Doll, R., Buckley, J.D. & Sporn, M.B. (1981) Can dietary beta carotene materially reduces human cancer rates? Nature 290, 201-208.
30. Block, G., Patterson, B. & Subar, A. (1992) Fruit, vegetables and cancer prevention: a review of the epidemiologic evidence. Nutr. Cancer 18, 1-29.
31. Ames, B.N., Gold, L.S. & Willett, W.C. (1995) The causes and prevention of cancer Proc. Natl. Acad. Sci. USA 92, 5258-5265.
32. Ames, B.N. & Gold, L.S. (1997) Environmental pollution, pesticides, and the prevention of cancer: misconceptions. FASEB J. 11, 1041-1052.
33. Michaud, D.S., Feskanich, D., Rimm, E.B., Colditz, G.A., Speizer, F.E., Willett, W.C. & Giovannuci, E. (2000) Intake of specific carotenoids and risk of lung cancer in 2 prospective US cohorts. Am. J. Clin. Nutr. 72, 990-997.
34. Albanes, D., Heinonen, O.P., Taylor, P.R., Virtamo, J., Edwards, B.K., Rauthalathi, M., Hartman, A.M., Palmgren, J., Freedman, L.S., Haapakoski, J., Barrett, M.J., Pietinen, P., Malila, N., Liipo, K., Salomaa, E.R., Tangrea, J.A., Teppo, L., Askin, F.B., Erozan, Y., Greenwald, P. & Huttunen, J.K. (1996) Tocopherol and carotene supplements and lung cancer incidence in the alpha tocopherol, beta carotene cancer prevention study: effects of base line characteristics and study compliance. J. Natl. Cancer Inst 88, 1560-1570.
35. Omenn, G.S., Goodman, G.E., Thornquist, M.D., Balmes, J., Cullen, M.R., Glass, A., Keogh, J.P., Meyskens, F.L., Valanis, B., Williams, J.H., Barnhart, S. & Hammar, S. (1996) Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 334, 1150-1155.
36. Hennekens, C.H., Buring, J.E., Manson, J.E., Stampfer, M., Rosner, B., Cook, N.R., Belanger, C., LaMotte, F., Gaziano, J.M., Ridker, P.M., Willet, W. & Peto, R. (1996) Lack of effect of long-term supplementation with beta-carotene on the incidence of malignant neoplasma and cardiovascular disease. N. Engl. J. Med. 334, 1145-1149.
37. Pryor, W.A., Stahl, W. & Rock, C.L. (2000) Beta-carotene: from biochemistry to clinical trials. Nutr. Rev. 58, 39-53.
38. Bowen, P.E., Mobarhan, S. & Smith, J.C. Jr (1993) Carotenoid absorption in humans. Methods Enzymol. 214, 3-16.
39. Omenn, G.S., Goodman, G.E., Thornquist, M.D., Balmes, J., Cullen, M.R., Glass, A., Keogh, J.P., Meyskens, F.L., Valanis, B., Williams, J.H., Barnhart, S., Cherniack, M.G., Brodkin, C.A. & Hammar, S. (1996) Risk factors for lung cancer and for interventions effects in CARET, beta-carotene and retinol efficacy trial. J. Natl. Cancer Inst. 88, 1550-1559.
40. Heber, D. (2000) Colorful cancer prevention: alpha carotene, lycopene and lung cancer. Am. J. Clin. Nutr. 72, 901-902.
41. Wang, X.D., Liu, C., Bronson, B.T., Smith, D.E., Krinsky, N.I. & Russell, R.M. (1999) Retinoid signaling and activator protein-1 expression in ferrets given carotene supplements and exposed to tobacco smoke. J. Natl. Cancer Inst. 91, 60-66.
42. Wolf, G. (2002) The effect of low and high doses of β-carotene and exposure to cigarette smoke on lungs of ferrets. Nutrition Rev. 60, 88-90.