Cefotaxime-resistant bacteria colonizing older people admitted to an acute care hospital

Journal of the American Geriatrics Society

Volumn 51, Issue 4, 2003, Pages 519-522

  Bonomo, Robert A ^a   Donskey, Curtis J ^a   Blumer, Jeffery L ^b   Hujer, Andrea M ^a   Hoyenm, Claudia K ^b   Jacobs, Michael R ^c   Whalen, Christopher C ^c   Salata, Robert A ^c  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Antibiotic resistance; Cefotaxime; Cephalosporinase; Long term care facilities

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORINASE; CIPROFLOXACIN; IMIPENEM; PIPERACILLIN PLUS TAZOBACTAM;

AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIUM CULTURE; BACTERIUM ISOLATE; CASE CONTROL STUDY; COMORBIDITY; CONTROLLED STUDY; DRUG SURVEILLANCE PROGRAM; ELDERLY CARE; FEMALE; GRAM NEGATIVE BACTERIUM; HUMAN; LOGISTIC REGRESSION ANALYSIS; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; PLASMID; PREVALENCE; PSEUDOMONAS AERUGINOSA;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CEFOTAXIME; DRUG RESISTANCE, BACTERIAL; FEMALE; GRAM-NEGATIVE BACTERIA; HOMES FOR THE AGED; HOSPITALIZATION; HUMANS; LOGISTIC MODELS; LONG-TERM CARE; MALE; NURSING HOMES;

EID: 0037392073     PISSN: 00028614     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1532-5415.2003.51161.x     Document Type: Article

References (27)

1. Yoshikawa TT, Epidemiology and unique aspects of aging and infectious diseases. Clin Infect Dis 2000;30:931-933.
2. John JF, Jr Ribner BS, Antibiotic resistance in long term care facilities. Infect Control Hosp Epidemiol 1991;12:245-250.
3. Weiner J, Quinn JP, Bradford PA et al. Multiple antibiotic resistant Klebsiella and E. coli in nursing homes. JAMA 1999;281:517-523.
4. Girlich D, Karim A, Poirel L et al. Molecular epidemiology of an outbreak due to IRT-2 β-lactamase-producing strains of Klebsiella pneumoniae in a geriatric department. J Antimicrob Chemother 2000;45:467-473.
5. Rice LB, Willey SH, Papanicolaou GA et al. Outbreak of ceftazidime-resistance caused by extended-spectrum β-lactamases at a Massachusetts chronic care facility. Antimicrob Agents Chemother 1990;34:2193-2199.
6. Bradford PA, Urban C, Jaiswal A et al. SHV-7, a novel cefotaxime-hydrolyzing β-lactamase, identified in Escherichia coli from hospitalized nursing home patients. Antimicrob Agents Chemother 1995;39:899-905.
7. Rice LB, Eckstein EC, DeVente J et al. Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center. Clin Infect Dis 1996;23:118-124.
8. Terpenning MS, Bradley SF, Wan JY et al. Colonization and infection with antibiotic-resistant bacteria in a long-term care facility. J Am Geriatr Soc 1994;42:1062-1069.
9. Bradley SF. Issues in the management of resistant bacteria in long-term-care facilities. Infect Control Hosp Epidemiol 1999;20:362-366.
10. Muder RR, Brennen C, Drenning SD et al. Multiply antibiotic-resistant gram-negative bacilli in a long-term-care facility. A case-control study of patient risk factors and prior antibiotic use. Infect Control Hosp Epidemiol 1997;18:809-813.
11. Mody L, Bradley SF, Strausbaugh LJ et al. Prevalence of ceftriaxone- and ceftazidime-resistant gram-negative bacteria in long-term-care facilities. Infect Control Hosp Epidemiol 2001;22:193-194.
12. Loeb M, Moss L, Stiller A et al. Colonization with multiresistant bacteria and quality of life in residents of long-term-care facilities. Infect Control Hosp Epidemiol 2001;22:67-68.
13. Nicolle LE, Bentley DW, Garibaldi R et al. Antimicrobial use in long-term-care facilities. SHEA Long-Term-Care Committee. Infect Control Hosp Epidemiol 2000;21:537-545.
14. Strausbaugh LJ, Crossley KB, Nurse BA et al. Antimicrobial resistance in long-term-care facilities. Infect Control Hospital Epidemiol 1996;17:129-140.
15. Leistevuo T, Toivonen P, Osterblad M et al. Problem of antimicrobial resistance of fecal aerobic gram-negative bacilli in the elderly. Antimicrob Agents Chemother 1996;40:2399-2403.
16. Levy SB, Marshall B, Schluederberg S et al. High frequency of antimicrobial resistance in human fecal flora. Antimicrob Agents Chemother 1988;32:1801-1806.
17. Salyers AA, Amabile-Cuevas CF. Why are antibiotic resistance genes so resistant to elimination? Antimicrob Agents Chemother 1997;41:2321-2325.
18. Donskey CJ, Chowdhry TK, Hecker MT et al. Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients. N Engl J Med 2000;343:1925-1932.
19. Landefeld CS, Palmer RM, Kresevic DM et al. A randomized trial of care in a hospital medical unit especially desinged to improve the functional outcomes of acutely ill older patietns. N Engl J Med 1995;332:1338-1344.
20. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. NCCLS publication no. M, 7-A, 4, National Committee for Clinical Laboratory Standards, Wayne PA, 1997, p. 7.
21. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disk susceptibility tests (NCCLS Publication no. M, 2-A, 6). Wayne, PA: National Committee for Clinical Laboratory Standards, 1997.
22. Box GEP, Hunter WG, Hunter JS. Statistics for Experimenters. An Introduction to Design, Data Analysis, and Model Building. New York: John Wiley, 1978.
23. Knaus WA, Draper EA, Wagner DP et al. APACHE II. A severity of disease classification system. Crit Care Med 1985;13:818-829.
24. Hoyen C, Rice LB, Conte S et al. Use of real time pulsed field gel electrophoresis to guide interventions during a nursery outbreak of Serratia marcescens infection. Pediatr Infect Dis 1999;18:357-360.
25. Tenover FC, Arbeit RD, Goering RV et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233-2239.
26. Hujer AM, Helfand MS, Page MGP et al. Development of a sensitive and specific enzyme linked immunosorbent assay detecting and quantifying CMY-2 and SHV β-lactamases. J Clin Microbiol, 2002;40:1947-1957.
27. Bauernfeind A, Chong Y, Lee K. Plasmid-encoded AmpC β-lactamases: How far have we gone 10 years after the discovery? Yonsei Med J 1998;39:520-525.