Human kallikrein 13 expression in normal tissues: An immunohistochemical study

Journal of Histochemistry and Cytochemistry

Volumn 51, Issue 4, 2003, Pages 493-501

  Petraki, Constantina D ^a   Karavana, Vassiliki N ^a   Diamandis, Eleftherios P ^b  

^a EVANGELISMOS HOSPITAL   (Greece)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Cancer biomarkers; Epithelial cell markers; Human kallikrein 13; Human kallikreins; Immunohistochemical expression; Serine proteases

Indexed keywords

BIOTIN; KALLIKREIN; KALLIKREIN 10; KALLIKREIN 13; KALLIKREIN 6; MONOCLONAL ANTIBODY; PARAFFIN; STREPTAVIDIN; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; ADRENAL MEDULLA; ARTICLE; CHOROID PLEXUS; CORPUS LUTEUM; ENDOCRINE GLAND; EPITHELIUM CELL; GENETIC CODE; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MOLECULAR CLONING; NERVE CELL; OVARY; OVARY FOLLICLE; PANCREAS; PARATHYROID GLAND; PERIPHERAL NERVOUS SYSTEM; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPERM; TESTIS; THYROID GLAND;

EID: 0037389551     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540305100411     Document Type: Article

References (35)

1. Anisowicz A, Sotiropoulou G, Stenman G, Mok SC, Sager R (1996) A novel protease homolog differentially expressed in breast and ovarian cancer. Mol Med 2:624-636
2. Bernett MJ, Blaber SI, Scarisbrick IA, Dhanarajan P, Thompson SM, Blaber M (2002) Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J Biol Chem 277:24562-24570
3. Blaber SI, Scarisbrick IA, Bernett MJ, Dhanarajan P, Seavy MA, Jin Y, Schwartz MA, et al. (2002) Enzymatic properties of rat myelencephalon-specific protease. Biochemistry 41:1165-1173
4. Black MH, Diamandis EP (2000) The diagnostic and prognostic utility of prostate specific antigen for diseases of the breast. Breast Cancer Res Treat 59:1-4
5. Black MH, Magklara A, Obiezu C, Levesque MA, Sutherland DJ, Tindall DJ, Young CY, et al. (2000) Expression of a prostate-associated protein, human glandular kallikrein (hK2), in breast tumors and in normal breast secretions. Br J Cancer 82:361-367
6. Bhoola KD, Figueroa CD, Worthy K (1992) Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol Rev 44:1-80
7. Chang A, Yousef GM, Jung K, Rajpert-de Meyts E, Diamandis EP (2001) Identification and molecular characterization of five novel kallikrein gene (KLK13; KLK14) splice variants: differential expression in the human testis and testicular cancer. Anticancer Res 21:3147-3152
8. Chu TM (1997) Prostate-specific antigen and early detection of prostate cancer. Tumor Biol 18:123-134
9. Coughlin SR (1999) How the protease thrombin talks to cells. Proc Natl Acad Sci USA 96:11023-11027
10. Diamandis EP, Okui A, Mitsui S, Luo LY, Soosaipillai A, Grass L, et al (2002) Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma. Cancer Res 62:295-300
11. Diamandis EP, Yousef GM, Clements J, Ashworth LK, Yoshida S, Egelrud T, Nelson PS, et al. (2000a) New nomenclature for the human tissue kallikrein gene family. Clin Chem 46:1855-1858
12. Diamandis EP, Yousef GM, Luo LY, Magklara A, Obiezu CV (2000b) The new human kallikrein gene family: implications in carcinogenesis. Trends Endocrinol Metab 11:54-60
13. Diamandis EP, Yousef GM, Petraki C, Soosaipillai AR (2000c) Human kallikrein 6 as a biomarker of Alzheimer's disease. Clin Biochem 33:663-667
14. Diamandis EP, Yousef GM, Soosaipillai AR, Bunting P (2000d) Human kallikrein 6 (zyme/protease M/neurosin): A new serum biomarker of ovarian carcinoma. Clin Biochem 33:579-583
15. Gomis-Ruth FX, Bayes A, Sotiropoulou G, Pampalakis G, Tsetsenis T, Villegas V, Aviles FX, et al. (2002) The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family. J Biol Chem 277:27273-27281
16. Jones TH, Figueroa CD, Smith C, Cullen DR, Bhoola KD (1990) Characterization of a tissue kallikrein in human prolactin-secreting adenomas. J Endocrinol 124:327-331
17. Kapadia C, Chang A, Sotiropoulou G, Yousef GM, Grass L, Soosaipillai A, Xing X, et al. (in press) Human kallikrein 13: Production and purification of recombinant protein, monoclonal and polyclonal antibodies and development of a sensitive and specific immunofluorometric assay. Clin Chem
18. Little SP, Dixon EP, Norris F, Buckley W, Becker GW, Johnson M, Dobbins JR, et al (1997) Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain. J Biol Chem 272:25135-25142
19. Luo L-Y, Bunting P, Scorilas A, Diamandis EP (2001a) Human kallikrein 10: a novel tumor marker for ovarian carcinoma? Clin Chim Acta 306:111-118
20. Luo LY, Grass L, Howarth DJC, Thibault P, Ong H, Diamandis EP (2001b) Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues. Clin Chem 47:237-246
21. Magklara A, Cheung CC, Asa SL, Diamandis EP (2000) Expression of prostate-specific antigen and human glandular kallikrein 2 in the thyroid gland. Clin Chim Acta 300:171-180
22. Mason AJ, Evans BA, Cox DR, Shine J, Richards RI (1983) Structure of mouse kallikrein gene family suggests a role in specific processing of biological active peptides. Nature 303:300-307
23. McCormack RT, Rittenhouse HG, Finlay JA, Sokoloff RL, Wang TJ, Wolfert RL, Lilja H, et al. (1995) Molecular forms of prostate-specific antigen and the human kallikrein gene family: a new era. Urology 45:729-744
24. Ogawa K, Yamada T, Tsujioka Y, Taguchi J, Takahashi M, Tsuboi Y, Fujino Y, et al (2000) Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease. Psychiatry Clin Neurosci 54:419-426
25. Okui A, Kominami K, Uemura H, Mitsui S, Yamaguchi N (2001) Characterization of a brain-related serine protease, neurosin (human kallikrein 6), in human cerebrospinal fluid. Neuroreport 12:1345-1350
26. Ole-MoiYoi OK, Pinkus GS, Spragg J, Austen KF (1979) Identification of human glandular kallikrein in the beta cell of the pancreas. N Engl J Med 300:1289-1294
27. Petraki C, Karavana VN, Luo LY, Diamandis EP (2002) Human kallikrein 10 expression in normal tissues by immunohistochemistry. J Histochem Cytochem 50:1247-1261
28. Petraki C, Karavana VN, Skoufogiannis PT, Little SP, Howarth DJC, Yousef GM, Diamandis EP (2001) The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues, as assessed by immunohistochemistry. J Histochem Cytochem 49:1431-1442
29. Pinkus GS, Maier M, Seldin DC, Ole-MoiYoi OK, Austen KF, Spragg J (1983) Immunohistochemical localization of glandular kallikrein in the endocrine and exocrine human pancreas. J Histochem Cytochem 31:1279-1288
30. Rittenhouse HG, Finlay JA, Mikolajczyk SD, Partin AW (1998) Human kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate. Crit Rev Clin Lab Sci 35:275-368
31. Vio CP, Roa JP, Silva R, Powers CA (1990) Localization of immunoreactive glandular kallikrein in lactotrophs of the rat anterior pituitary. Neuroendocrinology 51:10-14
32. Yamanaka H, He X, Matsumoto K, Shiosaka S, Yoshida S (1999) Protease M/neurosin mRNA is expressed in mature oligodendrocytes. Brain Res Mol Brain Res 71:217-224
33. Yousef GM, Chang A, Diamandis EP (2000) Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues. J Biol Chem 275:11891-11898
34. Yousef GM, Diamandis EP (2001) The new human tissue kallikrein gene family: structure, function, and association to disease. Endocrine Rev 22:184-204
35. Yousef GM, Luo LY, Diamandis E (1999) Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4. Anticancer Res 19:2843-2852