Reversible and irreversible inhibitory activity of succinic and maleic acid derivatives on acetylcholinesterase

European Journal of Pharmaceutical Sciences

Volumn 18, Issue 5, 2003, Pages 313-322

  Trujillo Ferrara, J ^a   Vázquez, Iván ^a   Espinosa, Judith ^a   Santillan, Rosa ^b   Farfán, Norberto ^b   Höpfl, Herbert ^c  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c CENTRO DE INVESTIGACIONES QUÍMICAS   (Mexico)

Author keywords

Acetylcholine; Acetylcholinesterase; Reversible and irreversible inhibitors; Succinic and maleic acids

Indexed keywords

COMPLEXATION; DISSOCIATION; ENZYMES; HYDROLYSIS; ORGANIC ACIDS;

DISSOCIATION CONSTANT;

DRUG PRODUCTS;

1H (4' HYDROXYPHENYL) 2,5 PYRROLIDINE DIONE; 1H PYRROLE 1 (4' HYDROXYPHENYL) 2,5 DIONE; 4 (4' ACETOXYPHENYLAMINO) 4 OXOPROPANOIC ACID; 4 (4' ACETYLOXYPHENYLAMINO) 4 OXOBUT 2 ENOIC ACID; 4 (4' HYDROXYPHENYLAMINO) 4 OXOBUT 2 ENOIC ACID; 4 (4' HYDROXYPHENYLAMINO) 4 OXOPROPANOIC ACID; ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; EDROPHONIUM; MALEIC ACID DERIVATIVE; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; DIALYSIS; DISSOCIATION CONSTANT; DRUG ACTIVITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; HYDROLYSIS; PRIORITY JOURNAL;

EID: 0037386106     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(03)00023-X     Document Type: Article

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