Outcome of positive antinuclear antibodies in individuals without connective tissue disease

Journal of Rheumatology

Volumn 30, Issue 4, 2003, Pages 736-739

  Myckatyn, Stephanie O ^a   Russell, Anthony S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Antinuclear antibodies; Connective tissue disease; Extractable nuclear antigens; Raynaud's phenomenon

Indexed keywords

ANTINUCLEAR ANTIBODY; CELL NUCLEUS ANTIGEN; DNA ANTIBODY; DOUBLE STRANDED DNA;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTHRALGIA; ARTICLE; BLOOD SAMPLING; CASE REPORT; CLINICAL FEATURE; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DATA BASE; DISEASE COURSE; EXTRACTION; FEMALE; FOLLOW UP; HEALTH SURVEY; HUMAN; HYPOTHYROIDISM; MALE; PRIORITY JOURNAL; RHEUMATOLOGY; SENSITIVITY AND SPECIFICITY; SEROLOGY; SYMPTOM; TELEPHONE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTINUCLEAR; CONNECTIVE TISSUE DISEASES; DATA COLLECTION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; RAYNAUD DISEASE; SENSITIVITY AND SPECIFICITY; TELEPHONE;

EID: 0037384636     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Slater CA, Davis RB, Shmerling RH. Antinuclear antibody testing. Arch Intern Med 1996;156:1421-5.
2. Tan EM, Feltkamp TEW, Smolen JS, et al. Range of antinuclear antibodies in healthy individuals. Arthritis Rheum 1997;40:1601-13.
3. Manoussakis MN, Tzioufas AG, Silis MP, Pange PJ, Goudevenos J, Moutsopoulos HM. High prevalence of anti-cardiolipin and other autoantibodies in a healthy elderly population. Clin Exp Immunol 1987;69:557-65.
4. Ruffatti AR, Rossi L, Calligaro A, et al. Autoantibodies of systemic rheumatic diseases in the healthy elderly. Gerontology 1990;36:104-11.
5. Vaile JH, Dyke L, Kherani R, Johnston C, Higgins T, Russell A. Is high titre ANA specific for connective tissue disease? Clin Exp Rheumatol 2000;18:433-8.
6. Hargraves M, Richmond M, Morton R. Presentation of two bone marrow elements: the 'tart' cell or LE cell. Mayo Clin Proc 1948;23:25-8.
7. Emlen W, O'Neill L. Clinical significance of antinuclear antibodies. Arthritis Rheum 1997;40:1612-8.
8. Vlachoyiannopoulos PG, Tzavara V, Dafni U, Spanos E, Moutsopoulos HM. Clinical features and evolution of antinuclear antibody positive individuals in a rheumatology outpatient clinic. J Rheumatol 1998;25:886-91.
9. de Vlam K, De Keyser F, Verbruggen G, et al. Detection and identification of antinuclear autoantibodies in the serum of normal blood donors. Clin Exp Rheumatol 1993;11:393-7.
10. Lahita RG. Sex steroids and the rheumatic diseases. Arthritis Rheum 1985;28:121-5.
11. Ansar AS, Penhale WJ, Talai N. Sex hormones, immune responses and autoimmune diseases. Am J Pathol 1985;121:531-51.
12. Goemaere S, Ackerman C, Goethals K, et al. Onset of symptoms of rheumatoid arthritis in relation to age, sex and menopausal transition. J Rheumatol 1990;17:1620-2.
13. Lock RJ, Unswoth DJ. Antibodies to extractable nuclear antigens. Has technological drift affected clinical interpretation? J Clin Pathol 2001;54:187-90.
14. Dayan CM, Daniels GH. Chronic autoimmune thyroiditis. N Engl J Med 1996;335:99-107.