Saralasin, a nonspecific angiotensin II receptor antagonist, attenuates oxidative stress and tissue injury in cerulein-induced acute pancreatitis

Pancreas

Volumn 26, Issue 3, 2003, Pages 224-229

  Ip, Siu Po ^a   Tsang, Siu Wai ^a   Wong, Tung Po ^a   Che, Chun Tao ^a   Leung, Po Sing ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Acute pancreatitis; Amylase; Oxidative stress; Pancreas; Renin angiotensin system; Saralasin

Indexed keywords

AMYLASE; CERULETIDE; FREE RADICAL; SARALASIN;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; ENZYME ACTIVITY; HISTOPATHOLOGY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TISSUE INJURY; TISSUE SPECIFICITY;

ACUTE DISEASE; ALPHA-AMYLASE; ANIMALS; CAERULEIN; GLUTATHIONE; LIPID PEROXIDATION; OXIDATIVE STRESS; PANCREAS; PANCREATITIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; SARALASIN;

EID: 0037380404     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200304000-00003     Document Type: Article

References (42)

1. Aho HJ, Nevalainen TJ, Havia VT, et al. Human acute pancreatitis: a light and electron microscopic study. Acta Pathol Microbiol Immunol Scand [A] 1982;90: 367-73.
2. Dabrowski A, Konturek SJ, Konturek JW, et al. Role of oxidative stress in the pathogenesis of caerulein-induced acute pancreatitis. Eur J Pharmacol 1999;377: 1-11.
3. Sanfey H, Bulkley GB, Cameron JL. The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis. Ann Surg 1984;200:405-13.
4. Guice KS, Miller DE, Oldham KT, et al. Superoxide dismutase and catalase: a possible role in established pancreatitis. Am J Surg 1986;151:163-9.
5. Telek G, Regoly-Merei J, Kovacs GC, et al. The first histologic demonstration of pancreatic oxidative stress in human acute pancreatitis. Hepatogastroenterology 2001;48:1252-8.
6. Rau B, Bauer A, Wang A, et al. Modulation of endogenous nitric oxide synthase in experimental acute pancreatitis: role of anti-ICAM-1 and oxygen free radical scavengers. Ann Surg 2001;233:195-203.
7. Czako L, Takacs T, Varga IS, et al. Oxidative stress in distant organs and the effects of allopurinol during experimental acute pancreatitis. Int J Pancreatol 2000;27:209-16.
8. Rau B, Poch B, Gansauge F, et al. Pathophysiologic role of oxygen free radicals in acute pancreatitis: initiating event or mediator of tissue damage? Ann Surg 2000;231:352-60.
9. Leung PS, Chan WP, Nobiling R. Regulated expression of pancreatic reninangiotensin system in experimental pancreatitis. Mol Cell Endocrinol 2000;166: 121-8.
10. Ip Sp, Kwan PC, Williams CH, et al. Changes of angiotensin-converting enzyme activity in the pancreas of chronic hypoxia and acute pancreatitis. Int J Biochem Cell Biol 2003;35 (in press).
11. Qi W, Tan DX, Reiter RJ, et al. Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats. Dig Dis Sci 1999;44: 2257-62.
12. Ip SP, Chan YW, Che CT, et al. Effect of chronic hypoxia on glutathione status and membrane integrity in the pancreas. Pancreatology 2002;2:34-9.
13. Godin DV, Garnett ME. Species-related variations in tissue antioxidant status: II. Differences in susceptibility to oxidative challenge. Comp Biochem Physiol [B] 1992;103:743-8.
14. Reed DJ, Babson JR, Beatty PW, et al. High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal Biochem 1980;106:55-62.
15. Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 1994;233:357-63.
16. Friess H, Weber A, Buchler M. Standards in monitoring acute experimental pancreatitis. Eur Surg Res 1992;24:1-13.
17. Schulz HU, Niederau C, Klonowski-Stumpe H, et al. Oxidative stress in acute pancreatitis. Hepatogastroenterology 1999;46:2736-50.
18. Reinheckel T, Prause J, Nedelev B, et al. Oxidative stress affects pancreatic proteins during the early pathogenesis of rat caerulein pancreatitis. Digestion 1999;60:56-62.
19. Reinheckel T, Nedelev B, Prause J, et al. Occurrence of oxidatively modified proteins: an early event in experimental acute pancreatitis. Free Radic Biol Med 1998;24:393-400.
20. Luthen R, Niederau C, Grendell JH. Intrapancreatic zymogen activation and levels of ATP and glutathione during caerulein pancreatitis in rats. Ann J Physiol 1995;268:G592-G604.
21. Dabrowski A, Gabryelewicz A. Oxidative stress: an early phenomenon characteristic of acute experimental pancreatitis. Int J Pancreatol 1992;12:193-9.
22. Kruse P, Anderson ME, Loft S. Minor role of oxidative stress during intermediate phase of acute pancreatitis in rats. Free Radic Biol Med 2001;30:309-17.
23. Leung PS, Carlsson PO. Tissue renin-angiotensin system: its expression, localization, regulation and potential role in the pancreas. J Mol Endocrinol 2001;26: 155-64.
24. Wallig MA. Xenobiotic metabolism, oxidant stress and chronic pancreatitis. Focus on glutathione. Digestion 1998;59 Suppl 4:13-24.
25. Alsfasser G, Gock M, Herzog L, et al. Glutathione depletion with L-buthionine(S,R)-sulfoximine demonstrates deleterious effects in acute pancreatitis of the rat. Dig Dis Sci 2002;47:1793-9.
26. Neuschwander-Tetri BA, Ferrell LD, Sukhabote RJ, et al. Glutathione monoethyl estcr ameliorates caerulein-induced pancreatitis in the mouse. J Clin Invest 1992; 89:109-16.
27. Demols A, Van Laethem JL, Quertinmont E, et al. N-acetylcysteine decreases severity of acute pancreatitis in mice. Pancreas 2000;20:161-9.
28. Nicotera P, McConkey D, Svensson SA, et al. Correlation between cytosolic Ca2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress. Toxicology 1988;52:55-63.
29. Czako L, Takacs T, Varga IS, et al. Involvement of oxygen-derived free radicals in L-arginine-induced acute pancreatitis. Dig Dis Sci 1998;43:1770-7.
30. Norman JG. New approaches to acute pancreatitis: role of inflammatory mediators. Digestion 1999;60(Suppl 1):57-60.
31. Dijkhorst-Oei LT, Stroes ES, Koomans HA, et al. Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo. J Cardiovasc Pharmacol 1999;33:420-4.
32. Griendling KK, Minieri CA, Ollerenshaw JD, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994;74:1141-8.
33. Jaimes EA, Galceran JM, Raij L. Angiotensin II induces superoxide anion production by mesangial cells. Kidney Int 1998;54:775-84.
34. Warnholtz A, Nickenig G, Schulz E, et al. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation 1999;99:2027-33.
35. Pagano PJ, Chanock SJ, Siwik DA, et al. Angiotensin II induces p67phox mRNA expression and NADPH oxidase superoxide generation in rabbit aortic adventitial fibroblasts. Hypertension 1998;32:331-7.
36. Leung PS. Local renin-angiotensin system in the pancreas: the significance of changes by chronic hypoxia and acute pancreatitis. JOP 2001;2:3-8.
37. Niederau C, Niederau M, Borchard F, et al. Effects of antioxidants and free radical scavengers in three different models of acute pancreatitis. Pancreas 1992; 7:486-96.
38. Wisner J, Green D, Ferrell L, et al. Evidence for a role of oxygen derived free radicals in the pathogenesis of caerulein induced acute pancreatitis in rats. Gut 1988;29:1516-23.
39. Yu CM, Tipoe GL, Wing-Hon LK, et al. Effects of combination of angiotensinconverting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction. J Am Coll Cardiol 2001;38:1207-15.
40. Kuriyama S, Tomonari H, Abe A, et al. Beneficial effect of combination therapy with an angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor on overt proteinuria in a patient with type 1 diabetic nephropathy. Nephron 2000;86:529-30.
41. Iliopoulou A, Giannakopoulos G, Pagoy H, et al. Acute pancreatitis due to captopril treatment. Dig Dis Sci 2001;46:1882-3.
42. Muchnick JS, Mehta JL. Angiotensin-converting enzyme inhibitor-induced pancreatitis. Clin Cardiol 1999;22:50-1.