Prevalence of transaminase abnormalities in asymptomatic, healthy subjects participating in an Executive Health-Screening Program

Digestive Diseases and Sciences

Volumn 48, Issue 4, 2003, Pages 797-801

  Patt, Cary H ^a   Yoo, Hwan Y ^a   Dibadj, Kourosh ^b   Flynn, John ^a   Thuluvath, Paul J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARBOR HOSPITAL   (United States)

Author keywords

Health screening; Liver; Transaminase

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME DEFECT; FEMALE; HUMAN; HUMAN EXPERIMENT; LOGISTIC REGRESSION ANALYSIS; MALE; MASS SCREENING; NORMAL HUMAN; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR;

ADULT; AGED; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BALTIMORE; BODY MASS INDEX; CHOLESTEROL; DIAGNOSIS, DIFFERENTIAL; FATTY LIVER; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MASS SCREENING; MIDDLE AGED; REFERENCE VALUES; RISK FACTORS; TRIGLYCERIDES;

EID: 0037380253     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022809430756     Document Type: Article

References (21)

1. Sherwood P, Lyburn I, Brown S, Ryder S: How are abnormal results for liver function tests dealt with in primary care? Audit of yield and impact. Br Med J 322:276-278, 2001
2. Pratt DS, Kaplan MM: Evaluation of abnormal liver-enzyme results in asymptomatic patients. N Engl J Med 342:1266-1271, 2000
3. Berasain C, Betés M, Panizo A, Ruiz J, Herrero JI, Civeira M-P, Prieto J: Pathological and virological findings in patients with persistent hypertransaminasaemia of unknown aetiology. Gut 47:429-435, 2000
4. Daniel S, Ben-Menachem T, Vasudevan G, Ma CK, Blumenkehl M: Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 94:3010-3014, 1999
5. Mathiesen UL, Franzén LE, Frydén A, Foberg U, Bodemar G: The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients. Scand J Gastroenterol 34:85-91, 1999
6. Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH, Driscoll CJ: Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 29:664-669, 1999
7. Poonawala A, Nair SP, Thuluvath PJ: Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study. Hepatology 32:689-692, 2000
8. Falck-Ytter Y, Younossi ZM, Marchesini G, McCullough AJ: Clinical features and natural history of nonalcoholic steatosis syndromes. Semin Liver Dis 21:17-26, 2001
9. Wanless IR, Lentz JS: Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors, Hepatology 12:1106-1110, 1990
10. Teli MR, James OF, Burt AD, Bennett MK, Day CP: The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 22:1714-1719, 1995
11. Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW: The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 11:74-80, 1990
12. James OFW, Day CP: Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance. J Hepatol 29:495-501, 1998
13. Diehl AM: Nonalcoholic steatohepatitis. Semin Liver Dis 19:221-229, 1999
14. Kumar KS, Malet PF: Nonalcoholic steatohepatitis. Mayo Clin Proc 75:733-739, 2000
15. Reid AE: Nonalcoholic steatohepatitis. Gastroenterology 121:710-723, 2001
16. Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R, Lin R, Samarasinghe D, Liddle C, Weltman M, George J: NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 35:373-379, 2002
17. United States Census Bureau. Population estimates. 2001. http://eire census.gov/popest/estimates.php
18. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri BA: Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 107:1103-1109, 1994
19. Dixon JB, Bhathal PS, O'Brien PE: Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 121:91-100, 2001
20. Pagano G, Pacini G, Musso G, Gambino R, Mecca F, Depetris N, Cassader M, David E, Cavallo-Perin P, Rizzetto M: Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association. Hepatology 35:367-372, 2002
21. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Lui YC, McCullough AJ: Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 116:1413-1419, 1999