Vitamin C improves resistance but not conduit artery endothelial function in patients with chronic renal failure

Kidney International

Volumn 63, Issue 4, 2003, Pages 1433-1442

  Cross, Jenny M ^a   Donald, Ann E ^b   Nuttall, Sarah L ^b   Deanfield, John E ^b   Woolfson, Robin G ^b   MacAllister, Raymond J ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NONE

Author keywords

Antioxidants; Atherosclerosis; Endothelial function; Renal failure; Vitamin C

Indexed keywords

ACETYLCHOLINE; ASCORBIC ACID; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; FEMALE; FOREARM BLOOD FLOW; HEMODIALYSIS; HUMAN; MALE; OXIDATIVE STRESS; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL;

EID: 0037377643     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00852.x     Document Type: Article

References (50)

1. BROWN JH, HUNT LP, VITES NP, et al: Comparative mortality from cardiovascular disease in patients with chronic renal failure. Nephrol Dial Transplant 9:1136-1142, 1994
2. AGODOA L: United States Renal Data System (USRDS). Nefrologia 20(Suppl 5):13-16, 2000
3. TIMIMI FK, TING HH, HALEY EA, et al: Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am Coll Cardiol 31:552-557, 1998
4. TING HH, TIMIMI FK, BOLES KS, et al: Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 97:22-28, 1996
5. TING HH, TIMIMI FK, HALEY EA, et al: Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels of humans with hypercholesterolemia. Circulation 95:2617-2622, 1997
6. SOLZBACH U, HORNIG B, JESERICH M, JUST H: Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation 96:1513-1519, 1997
7. LEVINE GN, FREI B, KOULOURIS SN, et al: Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 93:1107-1113, 1996
8. JESERICH M, SCHINDLER T, OLSCHEWSKI M, et al: Vitamin C improves endothelial function of epicardial coronary arteries in patients with hypercholesterolaemia or essential hypertension-assessed by cold pressor testing. Eur Heart J 20:1676-1680, 1999
9. GOKCE N, KEANEY JFJ, FREI B, et al: Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 99:3234-3240, 1999
10. DUFFY SJ, GOKCE N, HOLBROOK M, et al: Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension. Am J Physiol Heart Circ Physiol 280:H528-H534, 2001
11. DHALLA NS, TEMSAH RM, NETTICADAN T: Role of oxidative stress in cardiovascular diseases. J Hypertens 18:655-673, 2000
12. CLERMONT G, LECOUR S, LAHET J, et al: Alteration in plasma antioxidant capacities in chronic renal failure and hemodialysis patients: A possible explanation for the increased cardiovascular risk in these patients. Cardiovasc Res 47:618-623, 2000
13. TADDEI S, VIRDIS A, GHIADONI L, et al: Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 97:2222-2229, 1998
14. WILLIAMS MJ, SUTHERLAND WH, MCCORMICK MP, et al: Vitamin C improves endothelial dysfunction in renal allograft recipients. Nephrol Dial Transplant 16:1251-1255, 2001
15. BOAZ M, SMETANA S, WEINSTEIN T, et al: Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial. Lancet 356:1213-1218, 2000
16. CALVER A, COLLIER J, MONCADA S, VALLANCE P: Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: The nitric oxide dilator mechanism appears abnormal. J Hypertens 10:1025-1031, 1992
17. COCKCROFT JR, SCIBERRAS DG, GOLDBERG MR, RITTER JM: Comparison of angiotensin-converting enzyme inhibition with angiotensin II receptor antagonism in the human forearm. J Cardiovasc Pharmacol 22:579-584, 1993
18. WHITEHEAD TP, THORPE GHG, MAXWELL SRJ: Enhanced chemiluminescent assay for antioxidant capacity in biological fluids. Anal Chim Acta 266:265-277, 1992
19. MILNE DB, BOTNEN J: Retinol, alpha-tocopherol, lycopene, and alpha- and beta-carotene simultaneously determined in plasma by isocratic liquid chromatography. Clin Chem 32:874-876, 1986
20. NAGY E, DEGRELL I: Determination of ascorbic acid and dehydroascorbic acid in plasma and cerebrospinal fluid by liquid chromatography with electrochemical detection. J Chromatogr 497:276-281, 1989
21. BEUTLER E, GELBART T: Plasma glutathione in health and in patients with malignant disease. J Lab Clin Med 105:581-584, 1985
22. NOUROOZ-ZADEH J, TAJADDINI-SARMADI J, WOLFF SP: Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine. Anal Biochem 220:403-409, 1994
23. THAMBYRAJAH J, LANDRAY MJ, MCGLYNN FJ, et al: Abnormalities of endothelial function in patients with predialysis renal failure. Heart 83:205-209, 2000
24. VAN GULDENER C, LAMBERT J, JANSSEN MJ, et al: Endothelium-dependent vasodilatation and distensibility of large arteries in chronic haemodialysis patients. Nephrol Dial Transplant 12(Suppl 2):14-18, 1997
25. VAN GULDENER C, JANSSEN MJ, LAMBERT J, et al: Endothelium-dependent vasodilatation is impaired in peritoneal dialysis patients. Nephrol Dial Transplant 13:1782-1786, 1998
26. ARNADOTTIR M, GUDNASON V, HULTBERG B: Treatment with different doses of folic acid in haemodialysis patients: Effects on folate distribution and aminothiol concentrations. Nephrol Dial Transplant 15:524-528, 2000
27. KARI JA, DONALD AE, VALLANCE DT, et al: Physiology and biochemistry of endothelial function in children with chronic renal failure. Kidney Int 52:468-472, 1997
28. MORRIS ST, MCMURRAY JJ, RODGER RS, JARDINE AG: Impaired endothelium-dependent vasodilatation in uraemia. Nephrol Dial Transplant 15:1194-1200, 2000
29. ANNUK M, LIND L, LINDE T, FELLSTROM B: Impaired endothelium-dependent vasodilatation in renal failure in humans. Nephrol Dial Transplant 16:302-306, 2001
30. JUNGERS P, CHAUVEAU P, BANDIN O, et al: Hyperhomocysteinemia is associated with atherosclerotic occlusive arterial accidents in predialysis chronic renal failure patients. Miner Electrolyte Metab 23:170-173, 1997
31. SOMMERBURG O, GRUNE T, HAMPL H, et al: Does treatment of renal anemia with recombinant erythropoietin influence oxidative stress in hemodialysis patients? Clin Nephrol 53:S23-S29, 2000
32. WANG S, EIDE TC, SOGN EM, et al: Plasma ascorbic acid in patients undergoing chronic haemodialysis. Eur J Clin Pharmacol 55:527-532, 1999
33. CEBALLOS-PICOT I, WITKO-SARSAT V, MERAD-BOUDIA M, et al: Glutathione antioxidant system as a marker of oxidative stress in chronic renal failure. Free Radic Biol Med 21:845-853, 1996
34. CHEN CK, LIAW JM, JUANG JG, LIN TH: Antioxidant enzymes and trace elements in hemodialyzed patients. Biol Trace Elem Res 58:149-157, 1997
35. MARTIN-MATEO MC, SANCHEZ-PORTUGAL M, IGLESIAS S, et al: Oxidative stress in chronic renal failure. Ren Fail 21:155-167, 1999
36. SHERMAN DL, KEANEY JFJ, BIEGELSEN ES, et al: Pharmacological concentrations of ascorbic acid are required for the beneficial effect on endothelial vasomotor function in hypertension. Hypertension 35:936-941, 2000
37. SCHETTLER V, WIELAND E, METHE H, et al: Oxidative stress during dialysis: effect on free radical scavenging enzyme (FRSE) activities and glutathione (GSH) concentration in granulocytes. Nephrol Dial Transplant 13:2588-2593, 1998
38. ELLIS GR, ANDERSON RA, LANG D, et al: Neutrophil superoxide anion-generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy. J Am Coll Cardiol 36:1474-1482, 2000
39. CHAMBERS JC, MCGREGOR A, JEAN-MARIE J, et al: Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation 99:1156-1160, 1999
40. SAMUNI A, ARONOVITCH J, GODINGER D, et al: On the cytotoxicity of vitamin C and metal ions. A site-specific Fenton mechanism. Eur J Biochem 137:119-124, 1983
41. PODMORE ID, GRIFFITHS HR, HERBERT KE, et al: Vitamin C exhibits pro-oxidant properties. Nature 392:559, 1998
42. PROTEGGENTE AR, REHMAN A, HALLIWELL B, RICE-EVANS CA: Potential problems of ascorbate and iron supplementation: pro-oxidant effect in vivo? Biochem Biophys Res Commun 277:535-540, 2000
43. HELLER R, MUNSCHER-PAULIG F, GRABNER R, TILL U: L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells. J Biol Chem 274:8254-8260, 1999
44. HUANG A, VITA JA, VENEMA RC, KEANEY JFJ: Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. J Biol Chem 275:17399-17406, 2000
45. BAKER TA, MILSTIEN S, KATUSIC ZS: Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. J Cardiovasc Pharmacol 37:333-338, 2001
46. MAY JM: How does ascorbic acid prevent endothelial dysfunction? Free Radic Biol Med 28:1421-1429, 2000
47. RAITAKARI OT, ADAMS MR, MCCREDIE RJ, et al: Oral vitamin C and endothelial function in smokers: short-term improvement, but no sustained beneficial effect. J Am Coll Cardiol 35:1616-1621, 2000
48. GISSI-PREVENZIONE: Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354:447-455, 1999
49. STEPHENS NG, PARSONS A, SCHOFIELD PM, et al: Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347:781-786, 1996
50. HALLIWELL B: The antioxidant paradox. Lancet 355:1179-1180, 2000