Different glycosylation profile of serum IgA1 in IgA nephropathy according to the glomerular basement membrane thickness: Normal versus thin

American Journal of Kidney Diseases

Volumn 41, Issue 3, 2003, Pages 558-564

  Linossier, Marie Thérèse ^b   Palle, Sabine ^b   Berthoux, François ^a  

^a HÔPITAL NORD   (France)

^b NONE

Author keywords

Galactosylation; Glomerular basement membrane (GBM) thickness; Immunoglobin A (IgA) nephropathy; Immunoglobin A (IgA) subclass 1 (IgA1); O glycans; Pathophysiology

Indexed keywords

AGGLUTININ; CREATININE; GALACTOSE; GLYCAN; IMMUNOGLOBULIN A1; JACALIN; LECTIN; N ACETYLGALACTOSAMINE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULUS BASEMENT MEMBRANE; GLYCOSYLATION; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; LECTIN BINDING; MALE; SIALYLATION; THICKNESS;

EID: 0037374054     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/ajkd.2003.50117     Document Type: Article

References (40)

1. D'Amico G: The commonest glomerulonephritis in the world: IgA nephropathy. Q J Med 64:709-727, 1987
2. 1 in immunoglobulin A nephropathy, anaphylactoid purpura nephritis and systemic lupus erythematosus. J Clin Invest 66:1432-1436, 1980
3. Monteiro RC, Halbwachs-Mecarelli L, Roque-Barreira MC, Noël LH, Berger J, Lesavre P: Charge and size of mesangial IgA in IgA nephropathy. Kidney Int 28:666-671, 1985
4. 1 immunoglobulin. II. Structure of the Oglycosidically linked oligosaccharide units. J Biol Chem 249:7270-7281, 1974
5. 1 and IgG in IgA nephropathy. Clin Exp Immunol 100:470-474, 1995
6. 1 Contrib Nephrol 111:66-72, 1995
7. Hiki Y, Tanaka A, Kokubo T, et al: Analyses of IgA1 hinge glycopeptides in IgA nephropathy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J Am Soc Nephrol 9:577-582, 1998
8. 1 molecules as a possible etiopathogenic factor in IgA nephropathy. Contrib Nephrol 104:172-182, 1993
9. Issacs KL, Miller P: Role of antigen size and change in immune complex glomerulonephritis-active induction of disease with dextran and its derivatives. Lab Invest 47:198-205, 1982
10. Leung JC, Tang SC, Lam MF, Chan TM, Lai KN: Charge-dependent binding of polymeric IgA1 to human mesangial cells in IgA nephropathy. Kidney Int 59:277-285, 2001
11. Berthoux FC, Laurent B, Koller JM, et al: Primary IgA glomerulonephritis with thin glomerular basement membrane: A peculiar pathological marker versus thin membrane nephropathy association. Contrib Nephrol 111:1-7, 1995
12. Berthoux FC, Laurent B, Alamartine E, Diab N: New subgroup of primary IgA nephritis with thin glomerular basement membrane (GBM): Syndrome or association. Nephrol Dial Transplant 11:558-559, 1996
13. Deprèle C, Koller JM, Alamartine E, et al: Clinical and pathological characteristics of primary IgA nephritis (IgAN) according to glomerular basement membrane (GBM) thickness: Normal vs thin. Nephrol Dial Transplant 13:97A, 1998 (abstr)
14. Shibuya N, Goldstein IJ, Broekaert WF, Nsimba-Lubaki M, Peeters B, Peumans WJ: The elderberry (Sambacus nigra L.) bark lectin recognizes the Neu5Ac(a2-6)Gal/ GalNAc sequence. J Biol Chem 262:1596-1601, 1987
15. Knibbs RN, Goldstein IJ, Ratcliffe RM, Shibuya N: Characterization of the carbohydrate binding specificity of the leukoagglutinating lectin from Maackia amurensis. Comparison with other sialic-specific lectins. J Biol Chem 266:83-88, 1991
16. Pemberton RT: Studies on the human red cell agglutinins of the swan mussel (Anodonta cygnea). Vox Sang 16:457-464, 1969
17. Sharon N, Lis H: Carbohydrate specificity, in Sharon N, Lis H (eds): Lectins. London, UK, Chapman & Hall, 1989, pp 37-46
18. Cosio FG, Falkenhain ME, Sedmak DD: Association of thin glomerular basement membrane with other glomerulopathies. Kidney Int 46:471-474, 1994
19. Yoshida K, Suzuki J, Suzuki S, Kume K, Suzuki H, Hujiki T: A case of IgA nephropathy in three sisters with thin basement membrane disease. Am J Nephrol 18:422-424, 1998
20. Auwardt R, Savige J, Wilson D: A comparison of the clinical and laboratory features of thin basement membrane disease (TBMD) and IgA glomerulonephritis (IgA GN). Clin Nephrol 52:1-4, 1999
21. Lemmink HH, Nillesen WN, Mochizuki T, et al: Benign familial hematuria due to mutation of the type IV collagen α4 gene. J Clin Invest 98:1114-1118, 1996
22. Kashtan CE: Alport syndrome and thin glomerular basement membrane disease. J Am Soc Nephrol 9:1736-1750, 1998
23. Buzza M, Wang YY, Dagher H, et al: Col4A4 mutation in thin basement membrane disease previously described in Alport syndrome. Kidney Int 60:480-483, 2001
24. Buzza M, Wilson D, Savige J: Segregation of hematuria in thin basement membrane disease with haplotypes at the loci for Alport syndrome. Kidney Int 59:1670-1676, 2001
25. 1 molecules from IgA nephropathy patients and normal individuals. Nephrology 3:85-89, 1997
26. 1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry. Biochem Biophys Res Commun 271:268-274, 2000
27. Baharaki D, Dueymes M, Perrichot R, et al: Aberrant glycosylation of IgA from patients with IgA nephropathy. Glycoconj J 13:505-511, 1996
28. 1, Fab, and Fc regions and the role of N-glycosylation on Fca receptor interactions. J Biol Chem 273:2260-2272, 1998
29. Dueymes M, Bendaoud B, Pennec YL, Youinou P: IgA glycosylation abnormalities in the serum of patients with primary Sjögren's syndrome. Clin Exp Rheumatol 13:247-250, 1995
30. Basset C, Durand V, Jamin C, et al: Increased N-linked glycosylation leading to oversialylation of monomeric immunoglobulin At from patients with Sjögren's syndrome. Scand J Immunol 51:300-306, 2000
31. Woodroffe AJ, Gormley AA, McKenzie PE, et al: Immunological studies in IgA nephropathy. Kidney Int 18:366-374, 1980
32. Van den Wall Bake AWL, Daha MR, Van der Ark A, Hiemstra PS, Radl J, Van Es LA: Serum levels and in vitro production of IgA subclasses in patients with primary IgA nephropathy. Clin Exp Immunol 74:115-120, 1988
33. Layward L, Allen AC, Hattersley JM, Harper SJ, Feehally J: Elevation of IgA in IgA nephropathy is localized in the serum and not saliva and is restricted to the IgA1 subclass. Nephrol Dial Transplant 8:25-28, 1993
34. Basset C, Devauchelle V, Durand V, et al: Glycosylation of immunoglobulin A influences its receptor binding. Scand J Immunol 50:572-579, 1999
35. Grossetete B, Launay P, Lehuen A, Jungers P, Bach JF, Monteiro RC: Down-regulation of Fc alpha receptors on blood cells of IgA nephropathy patients: Evidence for a negative regulatory role of serum IgA. Kidney Int 53:1321-1325, 1998
36. Barratt J, Greer MR, Pawluczyk IZ, et al: Identification of a novel Fc alpha receptor expressed by human mesangium cells. Kidney Int 57:1936-1948, 2000
37. Moura IC, Centelles MN, Arcos-Fajardo M, et al: Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy. J Exp Med 194:417-425, 2001
38. Hiki Y, Odani H, Takahashi M, et al: Mass spectrometry proves under-O-glycosylation of glomerular IgA1 in IgA nephropathy. Kidney Int 59:1077-1085, 2001
39. Allen AC, Bailey EM, Brenchley PE, Buck KS, Barratt J, Feehally J: Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: Observation in three patients. Kidney Int 60:969-973, 2001
40. 1 self-aggregation and adhesion to extracellular matrix proteins. J Am Soc Nephrol 9:2048-2054, 1998