The effect of vecuronium is enhanced by a large rather than a modest dose of gentamicin as compared with no preoperative gentamicin

Anesthesia and Analgesia

Volumn 96, Issue 3, 2003, Pages 750-754

  Dotan, Zohar A ^a,d   Hana, Rene ^b,e   Simon, Daniel ^b,e   Geva, Daniel ^b,e   Pfeffermann, Reuven A ^b,e   Ezri, Tiberiu ^c,d  

^a SHEBA MEDICAL CENTER   (Israel)

^b KAPLAN MEDICAL CENTER   (Israel)

^c WOLFSON MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

^e HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CALCIUM CHANNEL BLOCKING AGENT; CEFONICID; FENTANYL; GENTAMICIN; ISOFLURANE; MAGNESIUM; METRONIDAZOLE; NEOSTIGMINE; STEROID; SUXAMETHONIUM; THIOPENTAL; VECURONIUM;

ADULT; AGED; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG POTENTIATION; EXTUBATION; HUMAN; MAJOR CLINICAL STUDY; PREOPERATIVE PERIOD; PRIORITY JOURNAL;

EID: 0037371205     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000050280.59508.70     Document Type: Article

References (25)

1. Begg EJ, Barclay ML. Aminoglycosides: 50 years on. Br J Clin Pharmacol 1995;39:597-603.
2. Prins JM, Buller HR, Kuijper EJ, et al. Once versus thrice daily gentamicin in patients with serious infections. Lancet 1993;341:335-9.
3. Elhanan K, Siplovich L, Raz RJ. Gentamicin once-daily versus thrice-daily in children. J Antimicrob Chemother 1995;35:327-32.
4. Bakri FE, Pallett A, Smith AG, Duncombe AS. Once-daily versus multiple-daily gentamicin in empirical antibiotic therapy of febrile neutropenia following intensive chemotherapy. J Antimicrob Chemother 2000;45:383-6.
5. Thureen PJ, Reiter PD, Gresores A, et al. Once versus twice daily gentamicin dosing in neonates ≥34 weeks' gestation: costeffectiveness analyses. Pediatrics 1999;103:594-8.
6. Maller R, Ahrne H, Eilard T, et al. Efficacy and safety of amikacin in systemic infections when given as a single daily dose or in two divided doses. J Antimicrob Chemother 1991;27:121-8.
7. Gilbert DN, Lee BL, Dworkin RJ, et al. A randomized comparison of the safety and efficacy of once-daily gentamicin or thrice-daily gentamicin in combination with ticarcillin clavulanate. Am J Med 1998;105:182-91.
8. Barza M, Ioannidis JP, Cappelleri JC, Lau J. Single or multiple daily doses of aminoglycosides: a meta-analysis. BMJ 1996;312:338-45.
9. Jewesson P, Chow A, Wai A, et al. A double-blind, randomized study of three antimicrobial regimens in the prevention of infections after elective colorectal surgery. Diagn Microbiol Infect Dis 1997;29:155-65.
10. Rodolico G, Puleo S, Blandino G, et al. Colorectal surgery: short-term prophylaxis with clindamycin plus aztreonam or gentamicin. Rev Infect Dis 1991;13:S612-5.
11. Zelenitsky SA, Silverman RE, Duckworth H, Harding GK. A prospective, randomized, double-blind study of single high dose versus multiple standard dose gentamicin both in combination with metronidazole for colorectal surgical prophylaxis. J Hosp Infect 2000;46:135-40.
12. Wu G, Furlanut M. Predictions of serum vancomycin concentrations by means of six different equations for calculation of creatinine clearance. Int J Clin Pharmacol Res 1997;17:1-10.
13. Pichler M, Wang Z, Grabner-Weiss C, et al. Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics. Biochemistry 1996;35:14659-64.
14. Redman RS, Silinsky EM. Decrease in calcium currents induced by aminoglycoside antibiotics in frog motor nerve endings. Br J Pharmacol 1994;113:375-8.
15. Karatas Y, Ergun Y, Gocmen C, et al. Possible postsynaptic action of aminoglycosides in the frog rectus abdominis. Acta Med Okayama 2000;54:49-56.
16. Rupp SM, Castagnoli KP, Fisher DM, Miller RD. Pancuronium and vecuronium pharmacokinetics and pharmacodynamics in younger and elderly adults. Anesthesiology 1987;67:45-9.
17. Nicolau DP, Freeman CD, Belliveau PP, et al. Experience with a once-daily aminoglycoside program administered to 2,184 adult patients. Antimicrob Agents Chemother 1995;39:650-5.
18. Kronenfeld MA, Thomas SJ, Turndorf H. Recurrence of neuromuscular blockade after reversal of vecuronium in a patient receiving polymyxin/amikacin sternal irrigation. Anesthesiology 1986;65:93-4.
19. Gilbert TB, Jacobs SC, Quaddoura AA. Deafness and prolonged neuromuscular blockade following single-dose peritoneal neomycin irrigation. Can J Anaesth 1998;45:568-70.
20. Jedeikin R, Dolgunski E, Kaplan R, Hoffman S. Prolongation of neuromuscular blocking effect of vecuronium by antibiotics. Anaesthesia 1987;42:858-60.
21. Hague BA, Martinez EA, Hartsfield SM. Effects of high-dose gentamicin sulfate on neuromuscular blockade in halothaneanesthetized horses. Am J Vet Res 1997;58:1324-6.
22. Forsyth SF, Ilkiw JE, Hildebrand SV. Effect of gentamicin administration on the neuromuscular blockade induced by atracurium in cats. Am J Vet Res 1990;51:1675-8.
23. Dupuis J, Martin R, Tetrault J. Atracurium and vecuronium interaction with gentamicin and tobramycin. Can J Anaesth 1989;36:407-11.
24. Vanacker BF, Van de Walle J. The neuromuscular blocking action of vecuronium in normal patients and patients with no renal function and interaction vecuronium-tobramycin in renal transplant patients. Acta Anaesthesiol Belg 1986;37:95-9.
25. Wong J, Brown G. Does once daily dosing of aminoglycosides affect neuromuscular function? J Clin Pharm Ther 1996;21:407-11.