Convergence of mechanosensory inputs onto neuromodulatory serotonergic neurons in the leech

Journal of Neurobiology

Volumn 54, Issue 4, 2003, Pages 604-617

  Velazquez Ulloa N ^a   Blackshaw, S E ^b   Szczupak, L ^c   Trueta, C ^a   Garcia E ^d   De Miguel, F F ^a  

^a INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d UNIVERSIDAD DE COLIMA   (Mexico)

Author keywords

Leech; Modulation; Sensory neuron; Serotonin; Synaptic transmission

Indexed keywords

CALCIUM; MAGNESIUM; SEROTONIN;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BEHAVIOR; CELL ACTIVITY; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; ELECTRIC ACTIVITY; EXCITATORY POSTSYNAPTIC POTENTIAL; FREQUENCY DISCRIMINATION; GANGLION; INTERNEURON; LEECH; MECHANICAL STIMULATION; MECHANORECEPTOR; NERVE CELL; NERVE ROOT; NEUROMODULATION; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; SENSORY NERVE CELL; SENSORY STIMULATION; SEROTONINERGIC SYSTEM; SKIN STIMULATION; STIMULUS RESPONSE;

ACTION POTENTIALS; ANIMALS; CALCIUM; EXCITATORY POSTSYNAPTIC POTENTIALS; GANGLIA, INVERTEBRATE; LEECHES; MAGNESIUM; MECHANOTRANSDUCTION, CELLULAR; NEURONS; PHYSICAL STIMULATION; REACTION TIME; SEROTONIN; SKIN;

EID: 0037370605     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10184     Document Type: Article

References (41)

1. Baylor DA, Nicholls JG. 1969. Chemical and electrical synaptic connections between cutaneous mechanoreceptor neurones in the central nervous system of the leech. J Physiol Lond 203:591-609.
2. Blackshaw SE, Nicholls JG, Parnas I. 1988. Physiological responses receptive fields terminal arborizations of nociceptive cells in the leech. J Physiol Lond 326:251-260.
3. Bruns D, Riedel D, Klingauf J, Jahn R. 2000. Quantal release of serotonin. Neuron 28:205-220.
4. De-Miguel FF, Vargas-Caballero M, García-Perez E. 2001. Spread of synaptic potentials through electrical synapses in Retzius neurons of the leech. J Exp Biol 219:3241-3250.
5. DeRiemer SA, Macagno ER. 1981. Light microscopic analysis of contacts between pairs of identified leech neurons with combined use of horseradish peroxidase and lucifer yellow. J Neurosci 1:650-657.
6. Dieudonne S. 2001. Serotonergic neuromodulation in the cerebellar cortex: cellular synaptic and molecular basis. Neuroscientist 7:207-219.
7. Eckert R. 1963. Electrical interaction of paired ganglion cells in the leech. J Gen Physiol 46:573-587.
8. Edwards DH, Kravitz EA. 1997. Serotonin social status and aggression. Curr Opin Neurobiol 7:812-819.
9. Gu XN, Muller KJ, Young SR. 1991. Synaptic integration at a sensory-motor reflex in the leech. J Physiol Lond 441: 733-754.
10. Hagiwara S, Morita H. 1962. Electrotonic transmission between two nerve cells in the leech ganglion. J Neurophysiol 25:721-731.
11. Harris-Warrick RM, Marder E. 1991. Modulation of neural networks for behavior. Ann Rev Neurosci 14:39-57.
12. Henderson L. 1983. The role of 5-hydroxytryptamine as a transmitter between identified leech neurons in culture. J Physiol Lond 339:311-326.
13. Jacobs BL, Fornal CA. 1991. Activity of brain serotonergic neurons in the behaving animal. Pharmacol Rev 43:563-578.
14. Kravitz EA. 2000. Serotonin aggression: insights gained from a lobster model system speculations on the role of amine neurons in a complex behavior. J Comp Physiol [A] 186:221-238.
15. Kristan Jr WB. 1982. Sensory motor neurons responsible for the local bending response in leeches. J Exp Biol 96:161-180.
16. Lent CM. 1973. Retzius cells from segmental ganglia of four species of leeches: comparative neuronal geometry. Comp Biochem Physiol 44A:35-40.
17. Lewis JE, Kristan Jr WB. 1998a. Representation of touch location by a population of leech sensory neurons. J Neurophysiol 80:2584-2592.
18. Lewis JE, Kristan Jr WB. 1998b. Quantitative analysis of a directed behavior in the medicinal leech: implications for organizing motor output. J Neurosci 18:1571-1582.
19. Lewis JE, Kristan Jr WB. 1998c. A neuronal network for computing population vectors in the leech. Nature 391: 76-79.
20. Lockery SR, Kristan Jr WB. 1990. Distributed processing of sensory information in the leech II Identification of interneurons contributing to the local bending reflex. J Neurosci 10:1816-1829.
21. Mar A, Drapeau P. 1996. Modulation of conduction block in leech mechanosensory neurons. J Neurosci 16:4335-4343.
22. Marder E. 1996. Neural modulation: following your own rhythm. Curr Biol 6:119-121.
23. Mason A, Leake LD. 1978. Morphology of leech Retzius cells demonstrated by intracellular injection of horseradish peroxidase. Comp Biochem Physiol 61:213-216.
24. Muller KJ, McMahan UJ. 1976. The shapes of sensory motor neurones the distribution of their synapses in ganglia of the leech: a study using intracellular injection of horseradish peroxidase. Proc R Soc Lond B Biol Sci 194:481-499.
25. Nicholls JG, Baylor DA. 1968. Specific modalities and receptive fields of sensory neurons in CNS of the leech. J Neurophysiol 31:740-756.
26. Nicholls JG, Purves D. 1970. Monosynaptic chemical electrical connexions between sensory motor cells in the central nervous system of the leech. J Physiol 209:647-667.
27. Nusbaum MP, Friesen WO, Kristan Jr WB, Pierce RA. 1987. Neural mechanisms generating the leech swimming rhythm. J Comp Physiol 161A:355-366.
28. Nusbaum MP, Kristan Jr WB. 1986. Swim initiation in the leech by serotonin-containing interneurons cells 21 and 61. J Exp Biol 122:277-302.
29. Payton B. 1981. The structure of the leech nervous system. In: Muller KJ, Nicholls JG, Stent GS, editors. Neurobiology of the leech. New York: Cold Spring Harbor Laboratory, p 35-50.
30. Pinato G, Torre V. 2000. Coding adaptation during mechanical stimulation in the leech nervous system. J Physiol 529:747-767.
31. Raleigh MJ, McGuire MT, Brammer GL, Pollack DB, Yuwiler A. 1991. Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys. Brain Res 559:181-190.
32. Sahley CL. 1995. What we have learned from the study of learning in the leech. J Neurobiol 27:434-445.
33. Schmidt BJ, Jordan LM. 2000. The role of serotonin in reflex modulation locomotor rhythm production in the mammalian spinal cord. Brain Res Bull 53:689-710.
34. Smith PA, Sunderland AJ, Leake LD, Walker RJ. 1975. Cobalt staining and electrophysiological studies of Retzius cells in the leech Hirudo medicinalis. Comp Biochem Physiol 51A:655-661.
35. Szczupak L, Kristan Jr WB. 1995. Widespread mechanosensory activation of the serotonergic system of the medicinal leech. J Neurophysiol 74:2614-2624.
36. Trueta C, Mendez B, De-Miguel FF. 2003. Somatic exocytosis of serotonin mediated by L-type calcium channels in cultured leech neurones. J Physiol (Lond), in press.
37. Willard AL. 1981. Effects of serotonin on the generation of the motor program for swimming by the medicinal leech. J Neurosci 1:936-944.
38. Wilson RJ, Kristan Jr WB, Kleinhaus AL. 1996a. An increase in activity of serotonergic Retzius neurons may not be necessary for the consummatory phase of feeding in the leech Hirudo medicinalis. J Exp Biol 199:1405-1414.
39. Wilson RJ, Skierczynski BA, Meyer JK, Skalak R, Kristan Jr WB. 1996b. Mapping motor neuroneactivity to overt behavior in the leech I. Passive biomechanical properties of the body wall. J Comp Physiol [A] 178:637-654.
40. Wittenberg G, Loer CM, Adamo SA, Kristan Jr WB. 1990. Segmental specialization of neuronal connectivity in the leech. J Comp Physiol 167:453-459.
41. Zhang X, Wilson RJ, Li Y, Kleinhaus AL. 2000. Chemical thermal stimuli have short-lived effects on the Retzius cell in the medicinal leech. J Neurobiol 43:304-311.