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Volumn 79, Issue 929, 2003, Pages 127-132

Thalidomide and its derivatives: Emerging from the wilderness

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CYTOKINE; IMMUNOMODULATING AGENT; THALIDOMIDE; THALIDOMIDE DERIVATIVE;

EID: 0037367899     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pmj.79.929.127     Document Type: Review
Times cited : (73)

References (77)
  • 1
    • 47349113508 scopus 로고
    • Thalidomide and congenital abnormalities
    • McBride W. Thalidomide and congenital abnormalities. Lancet 1961;ii:1358.
    • (1961) Lancet , vol.2 , pp. 1358
    • McBride, W.1
  • 2
    • 0000962444 scopus 로고
    • Fragen aus der Praxis: Kindliche Missbildungen nach Medikament Einnahme wahrend der Graviditat?
    • Lenz W. Fragen aus der Praxis: kindliche Missbildungen nach Medikament Einnahme wahrend der Graviditat? Dtsch Med Wochenschr 1961;86:2555-6.
    • (1961) Dtsch Med Wochenschr , vol.86 , pp. 2555-2556
    • Lenz, W.1
  • 3
    • 0013805310 scopus 로고
    • Further observation with thalidomide in lepra reactions
    • Sheskin J. Further observation with thalidomide in lepra reactions. Lepr Rev 1965;36:183-7.
    • (1965) Lepr Rev , vol.36 , pp. 183-187
    • Sheskin, J.1
  • 4
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
    • Sampaio EP, Sarno EN, Galilly R, et al. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med 1991;173:699-703.
    • (1991) J Exp Med , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3
  • 5
    • 0028302647 scopus 로고
    • (S)-form of alpha-methyl-N(alpha)- phthalimidoglutarimide, but not its (R)-form, enhanced phorbol ester-induced tumor necrosis factor-alpha production by human leukemia cell HL-60: Implication of optical resolution of thalidomidal effects
    • Nishimura K, Hashimoto Y, Iwasaki S. (S)-form of alpha-methyl-N(alpha)- phthalimidoglutarimide, but not its (R)-form, enhanced phorbol ester-induced tumor necrosis factor-alpha production by human leukemia cell HL-60: implication of optical resolution of thalidomidal effects. Chem Pharm Bull (Tokyo) 1994;42:1157-9.
    • (1994) Chem Pharm Bull (Tokyo) , vol.42 , pp. 1157-1159
    • Nishimura, K.1    Hashimoto, Y.2    Iwasaki, S.3
  • 6
    • 2542509655 scopus 로고    scopus 로고
    • A double-blind study of the sedative effects of the thalidomide enantiomers in humans
    • Hoglund P, Eriksson T, Bjorkman S. A double-blind study of the sedative effects of the thalidomide enantiomers in humans. J Pharmacokinet Biopharm 1998;26:363-83.
    • (1998) J Pharmacokinet Biopharm , vol.26 , pp. 363-383
    • Hoglund, P.1    Eriksson, T.2    Bjorkman, S.3
  • 7
    • 36949061827 scopus 로고
    • Toxicity and teratogenicity of optical isomers of thalidomide
    • Fabro S, Smith RL, Williams RT. Toxicity and teratogenicity of optical isomers of thalidomide. Nature 1967;215:296.
    • (1967) Nature , vol.215 , pp. 296
    • Fabro, S.1    Smith, R.L.2    Williams, R.T.3
  • 8
    • 0018620980 scopus 로고
    • Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers
    • Blaschke G, Kraft H, Fickentscher K, et al. Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers. Arzneimittelforschung 1979;29:1640-2.
    • (1979) Arzneimittelforschung , vol.29 , pp. 1640-1642
    • Blaschke, G.1    Kraft, H.2    Fickentscher, K.3
  • 10
    • 0032435953 scopus 로고    scopus 로고
    • Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone
    • Trapnell CB, Donahue SR, Collins JM, et al. Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone. Clin Pharmacol Ther 1998;64:597-602.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 597-602
    • Trapnell, C.B.1    Donahue, S.R.2    Collins, J.M.3
  • 11
    • 0034822474 scopus 로고    scopus 로고
    • Thalidomide is distributed into human semen after oral dosing
    • Teo SK, Harden JL, Burke AB, et al. Thalidomide is distributed into human semen after oral dosing. Drug Metab Dispos 2001;29:1355-7.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1355-1357
    • Teo, S.K.1    Harden, J.L.2    Burke, A.B.3
  • 12
    • 0031669267 scopus 로고    scopus 로고
    • Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells
    • Rowland TL, McHugh SM, Deighton J, et al. Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells. Immunopharmacology 1998;40:11-20.
    • (1998) Immunopharmacology , vol.40 , pp. 11-20
    • Rowland, T.L.1    McHugh, S.M.2    Deighton, J.3
  • 13
    • 0033152341 scopus 로고    scopus 로고
    • Selective down-regulation of T cell and non-T cell-derived tumour necrosis factor alpha by thalidomide: Comparisons with dexamethasone
    • Rowland TL, McHugh SM, Deighton J, et al. Selective down-regulation of T cell and non-T cell-derived tumour necrosis factor alpha by thalidomide: comparisons with dexamethasone. Immunol Lett 1999;68:325-32.
    • (1999) Immunol Lett , vol.68 , pp. 325-332
    • Rowland, T.L.1    McHugh, S.M.2    Deighton, J.3
  • 14
    • 0031051039 scopus 로고    scopus 로고
    • Thalidomide reduces tumour necrosis factor-alpha production by human alveolar macrophages
    • Tavares JL, Wangoo A, Dilworth P, et al. Thalidomide reduces tumour necrosis factor-alpha production by human alveolar macrophages. Respir Med 1997;91:31-9.
    • (1997) Respir Med , vol.91 , pp. 31-39
    • Tavares, J.L.1    Wangoo, A.2    Dilworth, P.3
  • 15
    • 0036155980 scopus 로고    scopus 로고
    • Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn's disease
    • Bauditz J, Wedel S, Lochs H. Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn's disease. Gut 2002;50:196-200.
    • (2002) Gut , vol.50 , pp. 196-200
    • Bauditz, J.1    Wedel, S.2    Lochs, H.3
  • 16
    • 0029160273 scopus 로고
    • Thalidomide inhibits tumor necrosis factor-alpha production by lipopolysaccharide- and lipoarabinomannan-stimulated human microglial cells
    • Peterson PK, Hu S, Sheng WS, et al. Thalidomide inhibits tumor necrosis factor-alpha production by lipopolysaccharide- and lipoarabinomannan-stimulated human microglial cells. J Infect Dis 1995;172:1137-40.
    • (1995) J Infect Dis , vol.172 , pp. 1137-1140
    • Peterson, P.K.1    Hu, S.2    Sheng, W.S.3
  • 17
    • 0032726481 scopus 로고    scopus 로고
    • Immunomodulation by thalidomide and thalidomide analogues
    • Corral LG, Kaplan G. Immunomodulation by thalidomide and thalidomide analogues. Ann Rheum Dis 1999;58(suppl I):1107-13.
    • (1999) Ann Rheum Dis , vol.58 , Issue.SUPPL. I , pp. 1107-1113
    • Corral, L.G.1    Kaplan, G.2
  • 18
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira AL, Sampaio EP, Zmuidzinas A, et al. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med 1993;77:1675-80.
    • (1993) J Exp Med , vol.77 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3
  • 19
    • 0035933772 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity
    • Keifer JA, Guttridge DC, Ashburner BP, et al. Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity. J Biol Chem 2001;276:22382-7.
    • (2001) J Biol Chem , vol.276 , pp. 22382-22387
    • Keifer, J.A.1    Guttridge, D.C.2    Ashburner, B.P.3
  • 20
    • 0029922290 scopus 로고    scopus 로고
    • Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-alpha by mononuclear cells
    • Shannon EJ, Sandoval F. Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-alpha by mononuclear cells. Immunopharmacol Immunotoxicol 1996;18:59-72.
    • (1996) Immunopharmacol Immunotoxicol , vol.18 , pp. 59-72
    • Shannon, E.J.1    Sandoval, F.2
  • 21
    • 0028928143 scopus 로고
    • The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures
    • McHugh SM, Rifkin IR, Deighton J, et al. The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures. Clin Exp Immunol 1995;99:160-7.
    • (1995) Clin Exp Immunol , vol.99 , pp. 160-167
    • McHugh, S.M.1    Rifkin, I.R.2    Deighton, J.3
  • 22
    • 0031573214 scopus 로고    scopus 로고
    • Inhibition of IL-12 production by thalidomide
    • Moller DR, Wysocka M, Greenlee BM, et al. Inhibition of IL-12 production by thalidomide. J Immunol 1997;159:5157-61.
    • (1997) J Immunol , vol.159 , pp. 5157-5161
    • Moller, D.R.1    Wysocka, M.2    Greenlee, B.M.3
  • 23
    • 0033200056 scopus 로고    scopus 로고
    • Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients
    • Haslett PA, Klausner JD, Makonkawkeyoon S, et al. Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients. AIDS Res Hum Retroviruses 1999;15:1169-79.
    • (1999) AIDS Res Hum Retroviruses , vol.15 , pp. 1169-1179
    • Haslett, P.A.1    Klausner, J.D.2    Makonkawkeyoon, S.3
  • 24
    • 0037093854 scopus 로고    scopus 로고
    • Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity
    • Dredge K, Marriott JB, Todryk SM, et al. Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity. J Immunol 2002;168:4914-19.
    • (2002) J Immunol , vol.168 , pp. 4914-4919
    • Dredge, K.1    Marriott, J.B.2    Todryk, S.M.3
  • 26
    • 0031863851 scopus 로고    scopus 로고
    • Thalidomide inhibits corneal angiogenesis induced by vascular endothelial growth factor
    • Kruse FE, Joussen AM, Rohrschneider K, et al. Thalidomide inhibits corneal angiogenesis induced by vascular endothelial growth factor. Graefes Arch Clin Exp Ophthalmol 1998;236:461-6.
    • (1998) Graefes Arch Clin Exp Ophthalmol , vol.236 , pp. 461-466
    • Kruse, F.E.1    Joussen, A.M.2    Rohrschneider, K.3
  • 27
    • 0031171663 scopus 로고    scopus 로고
    • Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
    • Kenyon BM, Browne F, D'Amato RJ. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization. Exp Eye Res 1997;64:971-8.
    • (1997) Exp Eye Res , vol.64 , pp. 971-978
    • Kenyon, B.M.1    Browne, F.2    D'Amato, R.J.3
  • 28
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral LG, Haslett PA, Muller GW, et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 1999;163:380-6.
    • (1999) J Immunol , vol.163 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3
  • 29
    • 0032757642 scopus 로고    scopus 로고
    • Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis
    • Oliver SJ, Freeman SL, Corral LG, et al. Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis. Clin Exp Immunol 1999;118:315-21.
    • (1999) Clin Exp Immunol , vol.118 , pp. 315-321
    • Oliver, S.J.1    Freeman, S.L.2    Corral, L.G.3
  • 30
    • 0032531993 scopus 로고    scopus 로고
    • CC-3052: A water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production
    • Marriott JB, Westby M, Cookson S, et al. CC-3052: a water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production. J Immunol 1998;161:4236-43.
    • (1998) J Immunol , vol.161 , pp. 4236-4243
    • Marriott, J.B.1    Westby, M.2    Cookson, S.3
  • 31
    • 0015189572 scopus 로고
    • WHO co-ordinated short-term double- blind trial with thalidomide in the treatment of acute lepra reactions in male lepromatous patients
    • Iyer CG, Languillon J, Ramanujam K, et al. WHO co-ordinated short-term double- blind trial with thalidomide in the treatment of acute lepra reactions in male lepromatous patients. Bull World Health Organ 1971;45:719-32.
    • (1971) Bull World Health Organ , vol.45 , pp. 719-732
    • Iyer, C.G.1    Languillon, J.2    Ramanujam, K.3
  • 32
    • 0019160035 scopus 로고
    • The treatment of lepra reaction in lepromatous leprosy. Fifteen years' experience with thalidomide
    • Sheskin J. The treatment of lepra reaction in lepromatous leprosy. Fifteen years' experience with thalidomide. Int J Dermatol 1980;19:318-22.
    • (1980) Int J Dermatol , vol.19 , pp. 318-322
    • Sheskin, J.1
  • 33
    • 0036175514 scopus 로고    scopus 로고
    • Management of erythema nodosum leprosum by thalidomide: Thalidomide analogues inhibit M. leprae-induced TNFalpha production in vitro
    • Sampaio EP, Hernandez MO, Carvalho DS, et al. Management of erythema nodosum leprosum by thalidomide: thalidomide analogues inhibit M. leprae-induced TNFalpha production in vitro. Biomed Pharmacother 2002;56:13-19.
    • (2002) Biomed Pharmacother , vol.56 , pp. 13-19
    • Sampaio, E.P.1    Hernandez, M.O.2    Carvalho, D.S.3
  • 34
    • 0025330107 scopus 로고
    • Crossover study of thalidomide vs placebo in severe recurrent aphthous stomatitis
    • Revuz J, Guillaume JC, Janier M, et al. Crossover study of thalidomide vs placebo in severe recurrent aphthous stomatitis. Arch Dermatol 1990;126:923-7.
    • (1990) Arch Dermatol , vol.126 , pp. 923-927
    • Revuz, J.1    Guillaume, J.C.2    Janier, M.3
  • 35
    • 8244247121 scopus 로고    scopus 로고
    • Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection
    • National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group
    • Jacobson JM, Greenspan JS, Spritzler J, et al. Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med 1997;336:1487-93.
    • (1997) N Engl J Med , vol.336 , pp. 1487-1493
    • Jacobson, J.M.1    Greenspan, J.S.2    Spritzler, J.3
  • 36
    • 0032977309 scopus 로고    scopus 로고
    • Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection
    • National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group
    • Jacobson JM, Spritzler J, Fox L, et al. Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. J Infect Dis 1999;180:61-7.
    • (1999) J Infect Dis , vol.180 , pp. 61-67
    • Jacobson, J.M.1    Spritzler, J.2    Fox, L.3
  • 37
    • 0036175049 scopus 로고    scopus 로고
    • Thalidomide in Behçet's disease
    • Shek LP, Lim DL. Thalidomide in Behçet's disease. Biomed Pharmacother 2002;56:31-5.
    • (2002) Biomed Pharmacother , vol.56 , pp. 31-35
    • Shek, L.P.1    Lim, D.L.2
  • 38
    • 0032520803 scopus 로고    scopus 로고
    • Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo- controlled trial
    • Hamuryudan V, Mat C, Saip S, et al. Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo- controlled trial. Ann Intern Med 1998;128:443-50.
    • (1998) Ann Intern Med , vol.128 , pp. 443-450
    • Hamuryudan, V.1    Mat, C.2    Saip, S.3
  • 39
    • 0018410216 scopus 로고
    • Treatment of ulcerative colitis with thalidomide
    • Waters MF, Laing AB, Ambikapathy A, et al. Treatment of ulcerative colitis with thalidomide. BMJ 1979;i:792.
    • (1979) BMJ
    • Waters, M.F.1    Laing, A.B.2    Ambikapathy, A.3
  • 40
    • 0032714591 scopus 로고    scopus 로고
    • Thalidomide therapy for patients with refractory Crohn's disease: An open-label trial
    • Ehrenpreis ED, Kane SV, Cohen LB, et al. Thalidomide therapy for patients with refractory Crohn's disease: an open-label trial. Gastroenterology 1999;117:1271-7.
    • (1999) Gastroenterology , vol.117 , pp. 1271-1277
    • Ehrenpreis, E.D.1    Kane, S.V.2    Cohen, L.B.3
  • 41
    • 0032714405 scopus 로고    scopus 로고
    • An open-label pilot study of low- dose thalidomide in chronically active, steroid-dependent Crohn's disease
    • Vasiliauskas EA, Kam LY, Abreu-Martin MT, et al. An open-label pilot study of low- dose thalidomide in chronically active, steroid-dependent Crohn's disease. Gastroenterology 1999;117:1278-87.
    • (1999) Gastroenterology , vol.117 , pp. 1278-1287
    • Vasiliauskas, E.A.1    Kam, L.Y.2    Abreu-Martin, M.T.3
  • 42
    • 0036481989 scopus 로고    scopus 로고
    • Early studies on the safely and efficacy of thalidomide for symptomatic inflammatory bowel disease
    • Bariol C, Meagher AP, Vickers CR, et al. Early studies on the safely and efficacy of thalidomide for symptomatic inflammatory bowel disease. J Gastroenterol Hepatol 2002;17:135-9.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 135-139
    • Bariol, C.1    Meagher, A.P.2    Vickers, C.R.3
  • 43
    • 0035999145 scopus 로고    scopus 로고
    • An open-label study of thalidomide for maintenance therapy in responders to infliximab in chronically active and fistulizing refractory Crohn's disease
    • Sabate JM, Villarejo J, Lemann M, et al. An open-label study of thalidomide for maintenance therapy in responders to infliximab in chronically active and fistulizing refractory Crohn's disease. Aliment Pharmacol Ther 2002;16:1117-24.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1117-1124
    • Sabate, J.M.1    Villarejo, J.2    Lemann, M.3
  • 44
    • 0034692466 scopus 로고    scopus 로고
    • Thalidomide for the treatment of AIDS-associated wasting
    • Kaplan G, Thomas S, Fierer DS, et al. Thalidomide for the treatment of AIDS-associated wasting. AIDS Res Hum Retroviruses 2000;16:1345-55.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 1345-1355
    • Kaplan, G.1    Thomas, S.2    Fierer, D.S.3
  • 45
    • 0029295913 scopus 로고
    • Thalidomide treatment reduces tumor necrosis factor alpha production and enhances weight gain in patients with pulmonary tuberculosis
    • Tramontana JM, Utaipat U, Molloy A, et al. Thalidomide treatment reduces tumor necrosis factor alpha production and enhances weight gain in patients with pulmonary tuberculosis. Mol Med 1995;1:384-97.
    • (1995) Mol Med , vol.1 , pp. 384-397
    • Tramontana, J.M.1    Utaipat, U.2    Molloy, A.3
  • 46
    • 12444307384 scopus 로고    scopus 로고
    • Oesophageal cancer and cachexia: The effects of thalidomide on weight loss and lean body mass in a sequential (metabolic) study
    • Khan ZH, Simpson E, Cole AT, et al. Oesophageal cancer and cachexia: the effects of thalidomide on weight loss and lean body mass in a sequential (metabolic) study. Gut 2002;50(suppl II):A4.
    • (2002) Gut , vol.50 , Issue.SUPPL. II
    • Khan, Z.H.1    Simpson, E.2    Cole, A.T.3
  • 47
    • 0033857366 scopus 로고    scopus 로고
    • Potential novel uses of thalidomide: Focus on palliative care
    • Peuckmann V, Fisch M, Bruera E. Potential novel uses of thalidomide: focus on palliative care. Drugs 2000;60:273-92.
    • (2000) Drugs , vol.60 , pp. 273-292
    • Peuckmann, V.1    Fisch, M.2    Bruera, E.3
  • 48
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999;341:1565-71.
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 50
    • 0036195061 scopus 로고    scopus 로고
    • Production of proangiogenic cytokines during thalidomide treatment of multiple myeloma
    • Dmoszynska A, Bojarska-Junak A, Domanski D, et al. Production of proangiogenic cytokines during thalidomide treatment of multiple myeloma. Leuk Lymphoma 2002;43:401-6.
    • (2002) Leuk Lymphoma , vol.43 , pp. 401-406
    • Dmoszynska, A.1    Bojarska-Junak, A.2    Domanski, D.3
  • 51
    • 0037105593 scopus 로고    scopus 로고
    • Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma
    • Neben K, Mytilineos J, Moehler TM, et al. Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma. Blood 2002;100:2263-5.
    • (2002) Blood , vol.100 , pp. 2263-2265
    • Neben, K.1    Mytilineos, J.2    Moehler, T.M.3
  • 52
    • 0035883101 scopus 로고    scopus 로고
    • Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes
    • Raza A, Meyer P, Dutt D, et al. Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes. Blood 2001;98:958-65.
    • (2001) Blood , vol.98 , pp. 958-965
    • Raza, A.1    Meyer, P.2    Dutt, D.3
  • 54
    • 0034641526 scopus 로고    scopus 로고
    • Effect of thalidomide on gastrointestinal toxic effects of irinotecan
    • Govindarajan R, Heaton KM, Broodwater R, et al. Effect of thalidomide on gastrointestinal toxic effects of irinotecan. Lancet 2000;356:566-7.
    • (2000) Lancet , vol.356 , pp. 566-567
    • Govindarajan, R.1    Heaton, K.M.2    Broodwater, R.3
  • 55
    • 0036853297 scopus 로고    scopus 로고
    • Thalidomide-associated deep vein thrombosis and pulmonary embolism
    • Bennett C, Schumock G, Desai A, et al. Thalidomide-associated deep vein thrombosis and pulmonary embolism. Am J Med 2002;113:603-6.
    • (2002) Am J Med , vol.113 , pp. 603-606
    • Bennett, C.1    Schumock, G.2    Desai, A.3
  • 56
    • 0029758257 scopus 로고    scopus 로고
    • Rediscovering thalidomide: A review of its mechanism of action, side effects, and potential uses
    • Tseng S, Pak G, Washenik K, et al. Rediscovering thalidomide: a review of its mechanism of action, side effects, and potential uses. J Am Acad Dermatol 1996;35:969-79.
    • (1996) J Am Acad Dermatol , vol.35 , pp. 969-979
    • Tseng, S.1    Pak, G.2    Washenik, K.3
  • 57
    • 0032517486 scopus 로고    scopus 로고
    • Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis
    • Wolkenstein P, Latarjet J, Roujeau JC, et al. Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis. Lancet 1998;352:1586-9.
    • (1998) Lancet , vol.352 , pp. 1586-1589
    • Wolkenstein, P.1    Latarjet, J.2    Roujeau, J.C.3
  • 59
    • 0033754011 scopus 로고    scopus 로고
    • Response to thalidomide therapy in refractory chronic graft-versus-host disease
    • Browne PV, Weisdorf DJ, Defor T, et al. Response to thalidomide therapy in refractory chronic graft-versus-host disease. Bone Marrow Transplant 2000;26:865-9.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 865-869
    • Browne, P.V.1    Weisdorf, D.J.2    Defor, T.3
  • 60
    • 0026514939 scopus 로고
    • Thalidomide for the treatment of chronic graft-versus-host disease
    • Vogelsang GB, Farmer ER, Hess AD, et al. Thalidomide for the treatment of chronic graft-versus-host disease. N Engl J Med 1992;326:1055-8.
    • (1992) N Engl J Med , vol.326 , pp. 1055-1058
    • Vogelsang, G.B.1    Farmer, E.R.2    Hess, A.D.3
  • 61
    • 0034962328 scopus 로고    scopus 로고
    • Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease
    • Arora M, Wagner JE, Davies SM, et al. Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease. Biol Blood Marrow Transplant 2001;7:265-73.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 265-273
    • Arora, M.1    Wagner, J.E.2    Davies, S.M.3
  • 62
    • 0031921590 scopus 로고    scopus 로고
    • The effect of thalidomide and 2 analogs on collagen induced arthritis
    • Oliver SJ, Cheng TP, Banquerigo ML, et al. The effect of thalidomide and 2 analogs on collagen induced arthritis. J Rheumotol 1998;25:964-9.
    • (1998) J Rheumotol , vol.25 , pp. 964-969
    • Oliver, S.J.1    Cheng, T.P.2    Banquerigo, M.L.3
  • 64
    • 0029801341 scopus 로고    scopus 로고
    • An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis
    • Huizinga TW, Dijkmans BA, van der Velde EA, et al. An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis. Ann Rheum Dis 1996;55:833-6.
    • (1996) Ann Rheum Dis , vol.55 , pp. 833-836
    • Huizinga, T.W.1    Dijkmans, B.A.2    Van Der Velde, E.A.3
  • 65
    • 0032705663 scopus 로고    scopus 로고
    • Thalidomide in the treatment of refractory rheumatoid arthritis
    • Keesal N, Wasserman MJ, Bookman A, et al. Thalidomide in the treatment of refractory rheumatoid arthritis. J Rheumatol 1999;26:2344-7.
    • (1999) J Rheumatol , vol.26 , pp. 2344-2347
    • Keesal, N.1    Wasserman, M.J.2    Bookman, A.3
  • 66
  • 67
    • 0033769659 scopus 로고    scopus 로고
    • Immune stimulation in scleroderma patients treated with thalidomide
    • Oliver SJ, Moreira A, Kaplan G. Immune stimulation in scleroderma patients treated with thalidomide. Clin Immunol 2000;97:109-20.
    • (2000) Clin Immunol , vol.97 , pp. 109-120
    • Oliver, S.J.1    Moreira, A.2    Kaplan, G.3
  • 68
    • 0030843798 scopus 로고    scopus 로고
    • Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus: Experience in sixteen consecutive patients
    • Stevens RJ, Andujar C, Edwards CJ, et al. Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus: experience in sixteen consecutive patients. Br J Rheumatol 1997;36:353-9.
    • (1997) Br J Rheumatol , vol.36 , pp. 353-359
    • Stevens, R.J.1    Andujar, C.2    Edwards, C.J.3
  • 69
    • 0033226698 scopus 로고    scopus 로고
    • Differential alteration by thalidomide of the glutathione content of rat vs rabbit conceptuses in vitro
    • Hansen JM, Carney EW, Harris C. Differential alteration by thalidomide of the glutathione content of rat vs rabbit conceptuses in vitro. Reprod Toxicol 1999;13:547-54.
    • (1999) Reprod Toxicol , vol.13 , pp. 547-554
    • Hansen, J.M.1    Carney, E.W.2    Harris, C.3
  • 70
    • 0022980440 scopus 로고
    • The thalidomide syndrome: Risks of exposure and spectrum of malformations
    • Newman CG. The thalidomide syndrome: risks of exposure and spectrum of malformations. Clin Perinatol 1986;13:555-73.
    • (1986) Clin Perinatol , vol.13 , pp. 555-573
    • Newman, C.G.1
  • 71
    • 0033671461 scopus 로고    scopus 로고
    • The re-emergence of thalidomide: Results of a scientific conference
    • Neiger BL. The re-emergence of thalidomide: results of a scientific conference. Teratology 2000;62:432-5.
    • (2000) Teratology , vol.62 , pp. 432-435
    • Neiger, B.L.1
  • 72
    • 0032920883 scopus 로고    scopus 로고
    • Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity
    • Parman T, Wiley MJ, Wells PG. Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity. Nat Med 1999;5:582-5.
    • (1999) Nat Med , vol.5 , pp. 582-585
    • Parman, T.1    Wiley, M.J.2    Wells, P.G.3
  • 73
    • 0034674474 scopus 로고    scopus 로고
    • A possible role of N-cadherin in thalidomide teratogenicity
    • Thiele A, Thormann M, Hofmann HJ, et al. A possible role of N-cadherin in thalidomide teratogenicity. Life Sci 2000;67:457-61.
    • (2000) Life Sci , vol.67 , pp. 457-461
    • Thiele, A.1    Thormann, M.2    Hofmann, H.J.3
  • 74
    • 0034058818 scopus 로고    scopus 로고
    • Hypothesis: Thalidomide embryopathy-proposed mechanism of action
    • Stephens TD, Fillmore BJ. Hypothesis: thalidomide embryopathy-proposed mechanism of action. Teratology 2000;61:189-95.
    • (2000) Teratology , vol.61 , pp. 189-195
    • Stephens, T.D.1    Fillmore, B.J.2
  • 75
    • 0034947693 scopus 로고    scopus 로고
    • Thalidomide neuropathy in patients treated for metastatic prostate cancer
    • Molloy FM, Floeter MK, Syed NA, et al. Thalidomide neuropathy in patients treated for metastatic prostate cancer. Muscle Nerve 2001;24:1050-7.
    • (2001) Muscle Nerve , vol.24 , pp. 1050-1057
    • Molloy, F.M.1    Floeter, M.K.2    Syed, N.A.3
  • 76
    • 0027979817 scopus 로고
    • Thalidomide neuropathy incidence and clinico-electrophysiologic findings in 42 patients
    • Ochonisky S, Verroust J, Bastuji-Garin S, et al. Thalidomide neuropathy incidence and clinico-electrophysiologic findings in 42 patients. Arch Dermatol 1994;130:66-9.
    • (1994) Arch Dermatol , vol.130 , pp. 66-69
    • Ochonisky, S.1    Verroust, J.2    Bastuji-Garin, S.3
  • 77
    • 0028568310 scopus 로고
    • Guideline for the clinical use and dispensing of thalidomide
    • Powell RJ, Gardner-Medwin JM. Guideline for the clinical use and dispensing of thalidomide. Postgrad Med J 1994;70:901-4.
    • (1994) Postgrad Med J , vol.70 , pp. 901-904
    • Powell, R.J.1    Gardner-Medwin, J.M.2


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