Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population

Human Genetics

Volumn 112, Issue 3, 2003, Pages 310-318

  Molokhia, Mariam ^a   Hoggart, C ^a   Patrick, A L ^b   Shriver, M ^c   Parra, E ^c   Ye, J ^c   Silman, A J ^d   McKeigue, P M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b Kavanagh St Clinic   (Trinidad and Tobago)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d ARC Epidemiology Research Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFRICA; ARTICLE; BAYES THEOREM; CARIBBEAN ISLANDS; CHILDHOOD; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENVIRONMENTAL PARAMETERS; ETHNIC DIFFERENCE; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC DIFFERENCE; GENETIC MODEL; GENOME; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HOUSEHOLD; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT EDUCATION; PLESIOMORPHY; POPULATION GENETICS; PRIORITY JOURNAL; PROBABILITY; QUANTITATIVE TRAIT LOCUS MAPPING; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIAL STATUS; SYSTEMIC LUPUS ERYTHEMATOSUS; TRINIDAD AND TOBAGO; AGED; ALLELE; AMERICAN INDIAN; ANALYSIS OF VARIANCE; ASIAN; CASE CONTROL STUDY; CAUCASIAN; CHINA; ETHNOLOGY; GENETIC LINKAGE; GENETICS; INDIA; MIDDLE AGED; NEGRO; QUESTIONNAIRE; RISK; STATISTICAL MODEL;

INSERTION SEQUENCES;

ADULT; AFRICA, WESTERN; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; ALLELES; ANALYSIS OF VARIANCE; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; INDIA; INDIANS, NORTH AMERICAN; LINKAGE (GENETICS); LOGISTIC MODELS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; ODDS RATIO; QUESTIONNAIRES; TRINIDAD AND TOBAGO;

EID: 0037361423     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-002-0883-3     Document Type: Article

References (27)

1. Akey JM, Sosnoski D, Parra E, Dios S, Hiester K, Su B, Bonilla C, Jin L, Shriver MD (2001) Melting curve analysis of SNPs (McSNP): A gel-free and inexpensive approach for SNP genotyping. Biotechniques 30:358-367
2. Breslow NE, Day NE (1980) Statistical Methods in Cancer Research, Vol I. The Analysis of Case-Control Studies. International Agency for Research on Cancer, Lyon, pp 270-279
3. Catalano MA, Hoffmeier M (1989) Frequency of SLE among the ethnic groups of Hawaii. Arthritis Rheum 32:s30
4. Central Statistical Office Trinidad and Tobago (1992) Annual Statistical Digest No. 39. Population and Vital Statistics. Central Statistical Office, Trinidad and Tobago, p 9
5. Chakraborty R (1975) Estimation of race admixture - A new method. Am J Phys Anthropol 42:507-511
6. Chakraborty R, Weiss KM (1986) Frequencies of complex diseases in hybrid populations. Am J Phys Anthropol 70:489-503
7. Collins-Schramm HE, Phillips CM, Operario DJ, Lee JS, Weber JL, Hanson RL, Knowler WC, Cooper R, Li H, Seldin MF (2002) Ethnic-difference markers for use in mapping by admixture linkage disequilibrium. Am J Hum Genet 70:737-750
8. Darlu P, Sagnier PP, Bois E (1990) Genealogical and genetical African admixture estimations, blood pressure and hypertension in a Caribbean community. Ann Hum Biol 17:387-397
9. Fessel J (1974) Systemic lupus erythematosus in the community: Incidence, prevalence, outcome and first symptoms; The high prevalence in Black women. Arch Intern Med 134:1027-1035
10. Firkin BG, Howard MA, Radford N (1980) Possible relationship between lupus inhibitor and recurrent abortion in young women. Lancet II:366
11. Frank AO (1979) Apparent predisposition to systemic lupus erythematosus in Chinese patients in west Malaysia. Ann Rheum Dis 39:266-269
12. Greenwood BM (1968) Autoimmune disease and parasitic infections in Nigerians. Lancet II:380-382
13. Hopkinson ND, Doherty M, Powell RJ (1994) Clinical features and race specific incidence/prevalence rates of SLE in a geographically complete cohort of patients. Ann Rheum Dis 53:675-680
14. Johnson AE, Gordon C, Palmer RG, Bacon PA (1995) The prevalence and incidence of systemic lupus erythematosus in Birmingham, England. Relationship to ethnicity and country of birth. Arthritis Rheum 38:551-558
15. MacLean CH, Adams MS, Leyshon WC, Workman PL, Reed TE, Gershowitz H, Weitkamp LR (1974) Genetic studies on hybrid populations. III. Blood pressure in an American Black community. Am J Hum Genet 26:614-626
16. McKeigue PM (1998) Mapping genes that underlie ethnic differences in disease risk: Methods for detecting linkage in admixed populations by conditioning on parental admixture. Am J Hum Genet 63:241-251
17. McKeigue PM, Carpenter JR, Parra EJ, Shriver MD (2000) Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: Application to African-American populations. Ann Hum Genet 64:171-186
18. Molokhia M, McKeigue M (2000) Risk for rheumatic disease in relation to ethnicity and admixture. Arthritis Rheum 2:115-125
19. Molokhia M, McKeigue PM, Cuadrado M, Hughes G (2001) Systemic lupus erythematosus in migrants from west Africa compared with African-Caribbean people in the UK. Lancet 357:1414-1415
20. Nossent JC (1992) Systemic lupus erythematosus on the Caribbean island of Curacao: An epidemiological investigation. Ann Rheum Dis 51:1197-1201
21. Samanta A, Roy S, Feehally J, Symmons DPM (1992) The prevalence of diagnosed systemic lupus erythematosus in Whites and Indian Asian immigrants in Leicester city, UK. Br J Rheumatol 31:679-682
22. Serdula MK, Rhoads GG (1979) Frequency of systemic lupus erythematosus in different ethnic groups in Hawaii. Arthritis Rheum 22:328-333
23. StataCorp (2001) Stata Statistical Software: Release 7.0. Stata Corporation, College Station, Tex., USA
24. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271-1277
25. Theofilopoulos AN, Dixon FJ (1985) Murine models of systemic lupus erythematosus. Adv Immunol 37:269-390
26. Vyse TJ, Kotzin BL (1998) Genetic susceptibility to systemic lupus erythematosus. Annu Rev Immunol 16:261-292
27. Wang F, Wang CL, Tan CT, Manivasagar M (1997) Systemic lupus erythematosus in Malaysia: A study of 539 patients and comparison of prevalence and disease expression in different racial and gender groups. Lupus 6:248-253