Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice

Psychopharmacology

Volumn 166, Issue 3, 2003, Pages 276-283

  Liang, Jian Hui ^a   Wang, Xu Hua ^a   Liu, Rui Ke ^a   Sun, Hong Lei ^a   Ye, Xiang Feng ^a   Zheng, Ji Wang ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Buspirone; Calcium channel blocker; Fluoxetine; Nociception; Ryanodine; The hot plate test

Indexed keywords

5 HYDROXYTRYPTOPHAN; BUSPIRONE; CAFFEINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHLORIDE; CALCIUM ION; EGTAZIC ACID; FLUOXETINE; NIFEDIPINE; NIMODIPINE; RYANODINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; EXTRACELLULAR FLUID; FEMALE; HOT PLATE TEST; LATENT PERIOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; TIME SERIES ANALYSIS;

EID: 0037348983     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1327-4     Document Type: Article

References (63)

1. Bayliss DA, Li YW, Talley EM (1997) Effects of serotomn on caudal raphe neurons: inhibition of N- and P/Q-type calcium channels and the afterhyperpolarization. J Neurophysiol 77:1362-1374
2. Ben-Sreti MM, Gonzalez JP, Sewell RD (1983) Effects of elevated calcium and calcium antagonists on 6,7-benzomorphan-induced analgesia. Eur J Pharmacol 90:385-391
3. Berridge MJ (1998) Neuronal calcium signaling. Neuron 21:1326
4. Besson JM, Chaouch A (1987) Peripheral and spinal mechanisms of nociception. Physiol Rev 67:67-186
5. Cardenas CG, Del Mar LP, Scroggs RS (1995) Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties. J Neurophysiol 74:1870-1879
6. Chapman DB, Way EL (1982) Modification of endorphine/ enkephalin analgesia and stress-induced analgesia by divalent cations, a cation chelator and an ionophore. Br J Pharmacol 75:389-396
7. Chen Y, Penington NJ (1996) Differential effects of protein kinase C activation on 5-HT1A receptor coupling to Ca2+ and K+ currents in rat serotonergic neurones. J Physiol 496:129-137
8. Crisp T, Stafinsky JL, Spanos LJ, Uram M, Perni VC, Donepudi HB (1991) Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord. Gen Pharmacol 22:247-251
9. Damaj MI (2000) The involvement of spinal Ca2+/calmodulinprotein kinase II in nicotine-induced antinociception in mice. Eur J Pharmacol 404:103-110
10. Daval G, Verge D, Basbaum A, Bourgoin S, Hamon M (1987) Autoradiographic evidence of serotonin 1 binding sites on primary afferent fibers in the dorsal horn of the rat spinal cord. Neurosci Lett 83:71-76
11. Del Mar LP, Cardenas CG, Scroggs RS (1994) Serotonin inhibits high-threshold Ca2+ channel currents in capsaicin-sensitive acutely isolated adult-rat DRG neurons. J Neurophysiol 72:2551-2554
12. Dogrul A, Yesilyurt O (1998) Effects of intrathecally administered aminoglycoside antibiotics, calcium-channel blockers, nickel and calcium on acetic acid-induced writhing test in mice. Gen Pharmacol 30:613-616
13. Dogrul A, Yesilyurt O, Isimer A, Guzeldemir ME (2001) L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective μ opioid agonist, but not to selective δ and κ agonist at the level of the spinal cord in mice. Pain 93:61-68
14. Eide PK, Joly NM, Hole K (1990) The role of spinal cord 5-HT1A and 5-HT1B receptors in the modulation of a spinal nociceptive reflex. Brain Res 536:195-200
15. El-Yassir N, Fleetwood-Walker SM (1990) A 5-HT1-type receptor mediates the antinociceptive effect of nucleus raphe magus stimulation in the rat. Brain Res 523:92-99
16. Friel DD, Tsien RW (1992) A caffeine- and ryanodine-sensitive Ca2+ store in bullfrog sympathetic neurons modulates effects of Ca2+ entry on [Ca2+]i. J Physiol 450:217246
17. Galeotti N, Ghelardini C, Bartolini A (1997) 5-HT1A agonists induce central cholinergic antinociception. Pharmacol Biochem Behav 57:835-841
18. Giordano J, Rogers L (1989) Antinociceptive effects of the novel anxiolytic buspirone in three pain tests in rats. Pain 39:109-113
19. Giordano J, Rogers L (1992) Putative mechanisms of buspironeinduced antinociception in the rat. Pain 50:365-372
20. Gobert A, Rivet JM, Cistarelli L, Melon C, Millan MJ (1999) Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of α2-adrenergic receptors underlie its actions. Neuroscience 93:1251-1262
21. Haley TJ, McCormick WG (1957) Pharmacological effects produced by interacerebral injections of drugs in the conscious mouse. Br J Pharmacol 12:12-15
22. Hano K, Kaneto H, Kakunaga T (1964) Significance of Ca2+ ion in the morphine analgesia. Jpn J Pharmacol 14:227-229
23. Harris RA, Loh HH, Way EL (1975) Effects of divalent cations, cation chelators and an ionophore on morphine analgesia and tolerance. J Pharmcol Exp Ther 195:488-498
24. Jain NK, Kulkarni SK (1999) L-NAME, a nitric oxide synthase inhibitor, modulates cholinergic antinociception. Methods Find Exp Clin Pharmacol 21:161-165
25. Kakunaga T, Kaneto H, Hano K (1966) Pharmacologic studies on analgesics. VII. Significance of the calcium ion in morphine analgesia. J Pharmacol Exp Ther 153:134-141
26. Kitamura Y, Nagatani T, Watanabe T (1994) Buspirone enhances head twitch behavior in mice. Eur J Pharmacol 253:297-301
27. Koike H, Saito H, Matsuki N (1994) 5-HT1A receptor-mediated inhibition of N-type calcium current in acutely isolated ventromedial hypothalamic neuronal cells. Neurosci Res 19:161-166
28. Lin CH, Huang YC, Tsai JJ, Gean PW (2001) Modulation of voltage-dependent calcium currents by serotonin in acutely isolated rat amygdala neurons. Synapse 41:351-359
29. Lucas JJ, Mellstrom B, Colado MI, Naranjo JR (1993) Molecular mechanisms of pain: serotonin1A receptor agonists trigger transactivation by c-fos of the prodynorphin gene in spinal cord neurons. Neuron 10:599-611
30. Lucki I (1998) The spectrum of behaviors influenced by serotonin. Biol Psychiatry 44:151-162
31. Malmberg AB, Yaksh TL (1994) Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N-type and P-type channels inhibits formalin-induced nociception. J Neurosci 14:4882-4890
32. Malmberg AB, Yaksh TL (1995) Effect of continuous intrathecal infusion of ω-conopeptides, N-type calcium channel blockers, on behaviour and antinociception in the formalin and hot-plate tests in rats. Pain 60:83-90
33. McPherson PS, Kim YK, Valdivia H, Knudson CM, Takekura H, Franzini-Armstrong C, Coronado R, Campbell KP (1991) The brain ryanodine receptor: caffeine-sensitive Ca2+ release channel. Neuron 7:1725
34. Millan MJ (1994) Serotonin and pain: evidence that activation of 5HT1A receptors does not elicit antinociception against noxious thermal, mechanical and chemical stimuli in mice. Pain 58:45-61
35. Miranda HF, Paeile C (1990) Interaction between analgesics and calcium channel blockers. Gen Pharmacol 21:171-174
36. Miranda HF, Bustamante D, Kramer V, Pelissier T, Saavedra H, Paeile C, Fernandez E, Pinardi G (1992) Antinociceptive effects of Ca2+ channel blockers. Eur J Pharmacol 217:137-141
37. Omote K, Sonoda H, Kawamata M, Iwasaki H, Namiki A (1993) Potentiation of antinociceptive effects of morphine by calcium-channel blockers at the level of the spinal cord. Anesthesiology 79:746-752
38. Ormazabal MJ, Goicoechea C, Alfaro MJ, Sanchez E, Martin MI (1999) Study of mechanisms of calcitonin analgesia in mice: involvement of 5-HT3 receptors. Brain Res 845:130-138
39. Penington NJ, Fox AP (1995) Toxin-insensitive Ca2+ current in dorsal raphe neurons. J Neurosci 15:5719-5726
40. Penington NJ, Kelly JS (1990) Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron. Neuron 4:751-758
41. Protais P, Lesourd M, Comoy E (1998) Similar pharmacological properties of 8-OH-DPAT and alnespirone (S 20499) at dopamine receptors: comparison with buspirone. Eur J Pharmacol 352:179-187
42. Reader TA, Ase AR, Le Marec N, Lalonde R (2000) Differential effects of 1-trytophan and buspirone on biogenic amine contents and metabolism in Lurcher mice cerebellum. Neurosci Lett 280:171-174
43. Redrobe JP, Bourin M (1998) Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test. Psychopharmacology 138:198-206
44. Rhee JS, Ishibashi H, Akaike N (1996) Serotonin modulates highvoltage-activated Ca2+ channels in rat ventromedial hypothalamic neurons. Neuropharmacology 35:1093-1100
45. Roberts MH (1984) 5-Hydroxytryptamine and antinociception. Neuropharmacology 23:1529-1536
46. Robles LI, Barrios M, Del Pozo E, Dordal A, Baeyens JM (1996) Effects of K+ channel blockers and openers on antinociception induced by agonists of 5-HT1A receptors. Eur J Pharmacol 295:181-188
47. Rousseau E, Smith JS, Meissner G (1987) Ryanodine modifies conductance and gating behavior of single Ca2+ release channel. Am J Physiol 253:C364-C368
48. Saeki K, Obi I, Ogiku N, Hakamata Y, Matsumoto T (1998) Characterization of brain-type ryanodine receptor permanently expressed in Chinese hamster ovary cells. Life Sci 63:575-588
49. Smith FL, Stevens DL (1995) Calcium modulation of morphine analgesia: role of calcium channels and intracellular pool calcium. J Pharmacol Exp Ther 272:290-299
50. Strosznajder J, Chalimoniuk M, Samochocki M (1996) Activation of serotonergic 5-HT1A receptor reduces Ca2+o and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus. Neurochem Int 28:439-444
51. Suh HW, Song DK, Choi SR, Huh SO, Kim YH (1997) Differential effects of ω-conotoxin GVIA, nimodipine, calmidazolium and KN-62 injected intrathecally on the antinociception induced by β-endorphine, morphine and [D-Ala2, N-MePhe4, Gly-ol5]-enkephalin administered intracerebro-ventficularly in the mouse. J Pharmacol Exp Ther 282:961-966
52. Sun QQ, Dale N (1997) Serotonergic inhibition of the T-type and high voltage-activated Ca2+ currents in the primary sensory neurons of Xenopus larvae. J Neurosci 17:6839-6849
53. Sun QQ, Dale N (1998) Differential inhibition of N and P/Q Ca2+ currents by 5-HT1A and 5-HT1D receptors in spinal neurons of Xenopus larvae. J Physiol 510:103-120
54. Uphouse L (1997) Multiple serotonin receptors: too many, not enough, or just the fight number? Neurosci Biobehav Rev 21:679-698
55. Vocci FJ, Welch SP, Dewey WL (1980) Differential effects of divalent cation, cation chelators and an ionophore(A23187) on morphine and dibutyryl guanosine 3′, 5′-cyclic monophosphate antinociception. J Pharmacol Exp Ther 214:463-466
56. Wang JF, Han SP, Lu Z, Wang XJ, Han JS, Ren MF (1989) Effect of calcium ion on analgesia of opioid peptides. Int J Neurosci 47:279-285
57. Wang XP, Liang JH, Lu Y, Zhang Q, Liu RK, Ye XF, Li LJ (2002) Anti-aggressive action of imipramine and buspirone in isolated mice. Chin J Psychiatry 35:28-31
58. Warner R, Hudson-Howard L, Johnston C, Skolnick M (1990) Serotonin involvement in analgesia induced by transcranial electrostimulation. Life Sci 46:1131-1138
59. Wei ZY, Karim F, Roerig SC (1996) Spinal morphine/clonidine antinociceptive synergism: involvement of G proteins and N-type voltage-dependent calcium channels. J Pharmacol Exp Ther 278:1392-1407
60. Williams S, Serafin M, Muhlethaler M, Bernheim L (1998) The serotonin inhibition of high-voltage-activated calcium currents is relieved by action potential-like depolarizations in dissociated cholinergic nucleus basalis neurons of the guinea-pig. Eur J Neurosci 10:3291-3294
61. Wong CH, Wu WH, Zbuzek VK (1998) Hypotension does not alter the antinociceptive effect of nifedipine. Life Sci 63:343-348
62. Xu W, Qiu XC, Han JS (1994) Serotonin receptor subtypes in spinal antinociception in the rat. J Pharmacol Exp Ther 269:1182-1189
63. Zemlan FP, Murphy AZ, Behbehani MM (1994) 5-HT1A receptors mediate the effect of the bulbospinal serotonin system on spinal dorsal horn nociceptive neurons. Pharmacology 48:1-10