Constitutional isomers of Reactive Blue 2 - Selective P2Y-receptor antagonists?

European Journal of Medicinal Chemistry

Volumn 38, Issue 3, 2003, Pages 303-312

  Glänzel, Markus ^a   Bültmann, Ralph ^b   Starke, Klaus ^b   Frahm, August W ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Institute of Experimental and Clinical Pharmacology and Toxicology   (Germany)

Author keywords

Cibacron Blue 3GA; Guinea pig taenia coli; P2 receptor antagonist; P2X1 receptor; P2Y1 like receptor; Rat vas deferens; Reactive Blue 2

Indexed keywords

1 AMINO 4 [4 [4 CHLORO 6 (3 SULFOPHENYLAMINO) [1,3,5]TRIAZIN 2 YLAMINO] 3 SULFOPHENYLAMINO] 9,10 DIOXO 9,10 DIHYDROANTHRACENE 2 SULFONIC ACID; 1 AMINO 4 [4 [4 CHLORO 6 (4 SULFOPHENYLAMINO) [1,3,5]TRIAZIN 2 YLAMINO] 3 SULFOPHENYLAMINO] 9,10 DIOXO 9,10 DIHYDROANTHRACENE 2 SULFONIC ACID; ADENOSINE 5' O (2 THIOPHOSPHATE); ADENOSINE DERIVATIVE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CARBACHOL; CIBACRON BLUE F3GA; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHROMATOGRAPHY; COLON TENIA; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG PURIFICATION; DRUG SYNTHESIS; FEMALE; GUINEA PIG; IC 50; ISOMER; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; VAS DEFERENS;

EID: 0037345688     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(02)01449-6     Document Type: Article

References (40)

1. Ralevic V., Burnstock G. Pharmacol. Rev. 60:1998;413-492.
2. Williams M., Jarvis M.F. Biochem. Pharmacol. 59:2000;1173-1185.
3. Burnstock G., Williams M. J. Pharmacol. Exp. Ther. 295:2000;862-869.
4. Burnstock G. Clin. Med. 2:2002;45-53.
5. Kerr D.I.B., Krantis A. Proc. Austr. Physiol. Pharmacol. Soc. 10:1979;156-157.
6. Choo L.K. J. Pharm. Pharmacol. 33:1981;248-250.
7. Fischer Y., Becker C., Loken C. J. Biol. Chem. 274:1999;755-761.
8. Troadec J.D., Thirion S., Petturiti D., Poujeol P. Eur. J. Physiol. 440:2000;770-777.
9. Zenteno-Savin T., Sada-Ovalle I., Ceballos G., Rubio R. Eur. J. Pharmacol. 410:2000;15-23.
10. Silinsky E.M., Gerzanich V. J. Physiol. (London). 464:1993;197-212.
11. Connolly G.P., Harrison P.J. Eur. J. Pharmacol. 259:1994;95-99.
12. Khakh B.S., Humphrey P.P., Surprenant A. J. Physiol. (London). 484:1995;385-395.
13. Trezise D.J., Kennedy I., Humphrey P.P.A. Br. J. Pharmacol. 112:1994;282-288.
14. Suzuki H., Kokubun S. Br. J. Pharmacol. 112:1994;117-122.
15. Wiley J.S., Chen R., Jamieson G.P. Arch. Biochem. Biophys. 305:1993;54-60.
16. Brake A.J., Wagenbach M.J., Julius D. Nature (Washington, DC). 371:1994;519-523.
17. Bo X., Zhang Y., Nassar M., Burnstock G., Schöepfer R. FEBS Lett. 375:1995;129-133.
18. Bültmann R., Starke K. Naunyn-Schmiedeberg's Arch. Pharmacol. 349:1994;74-80.
19. McMillan M.K., Soltoff S.P., Cantley L.C., Rudel R.A., Talamo B.R. Br. J. Pharmacol. 108:1993;453-461.
20. Bo X., Fischer B., Maillard M., Jacobson K.A., Burnstock G. Br. J. Pharmacol. 112:1994;1151-1159.
21. Hansmann G., Bültmann R., Tuluc F., Starke K. Naunyn-Schmiedeberg's Arch. Pharmacol. 356:1997;641-652.
22. Lin W.W., Chuang D.M. J. Pharmacol. Exp. Ther. 269:1994;926-931.
23. Pfeilschifter J. Biochem. J. 272:1990;469-472.
24. Clonis Y.D., Labrou N.E., Kotsira V.Ph., Mazitsos C., Melissis S., Gogolas G. J. Chromatogr. 891:2000;33-44.
25. Denizli A., Piskin E. J. Biochem. Biophys. Methods. 49:2001;391-416.
26. Hanggi D., Carr P. Anal. Biochem. 149:1985;91-104.
27. Burton S.J., McLoughlin S.B., Stead C.V., Lowe C.R. J. Chromatogr. 435:1988;127-137.
28. Lowe C.R. Top Enzyme Ferment. Biotechnol. 9:1984;78-161.
29. Weber B.H., Willeford K., Moe J.G., Piszkiewicz D. Biochem. Biophys. Res. Commun. 86:1979;252-258.
30. Panchartek J., Allen Z.J., Muzik F. Col. Czech. Chem. Commun. 25:1960;2783-2799.
31. Society of Dyers and Colourists, Colour Index, Lund, Humphries, Bradford and London, vol. 3 and 4, third ed., Society of Dyers and Colourists, London, 1975
32. Foris A. Venkataraman K. Analytical Chemistry of Synthetic Dyes. 1977;217-254 Wiley-Interscience, New York.
33. Tuluc F., Bültmann R., Glänzel M., Frahm A.W., Starke K. Naunyn Schmiedeberg's Arch. Pharmacol. 357:1998;111-120.
34. Wojtkiewicz W., Kraska J. Chem. Abstr. 61:1964;16203f.
35. Pearson J.C., Burton S.J., Lowe C.R. Anal. Biochem. 158:1986;382-389.
36. Bültmann R., Starke K. Naunyn Schmiedeberg's Arch. Pharmacol. 352:1995;477-482.
37. Bültmann R., Pause B., Wittenburg H., Kurz G., Starke K. Naunyn Schmiedeberg's Arch. Pharmacol. 354:1996;481-490.
38. Bültmann R., Wittenburg H., Pause B., Kurz G., Nickel P., Starke K. Naunyn Schmiedeberg's Arch. Pharmacol. 354:1996;498-504.
39. Wittenburg H., Bültmann R., Pause B., Ganter C., Kurz G., Starke K. Naunyn Schmiedeberg's Arch. Pharmacol. 354:1996;491-497.
40. Cell Signalling & Neuroscience Product Catalogue, Sigma-Aldrich, Taufkirchen, Germany, 2002-2003, p. 738.