Importance of the kidneys in metabolism of vitamins A1 and A2 and their fatty acyl esters in mink feeding on fish-based diets and exposed to Aroclor 1242

Toxicology and Applied Pharmacology

Volumn 187, Issue 2, 2003, Pages 118-127

  Käkelä, Anne ^a,b   Käkelä, Reijo ^a   Hyvärinen, Heikki ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Aroclor 1242; Fatty acyl esters; Kidney; Mink; PCB; Vitamin A1; Vitamin A2; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; AROCLOR 1242; DEHYDRORETINOL; ESTER DERIVATIVE; FATTY ACID ESTER; POLYCHLORINATED BIPHENYL; RETINOL; RETINOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DIET; ESTERIFICATION; FEEDING; FEMALE; FISH; HERRING; KIDNEY METABOLISM; LIPID COMPOSITION; LIPID DIET; LIPID PEROXIDATION; LIVER; MINK; NONHUMAN; PLASMA; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TISSUE LEVEL; URINE LEVEL; VITAMIN METABOLISM;

CLUPEA; CLUPEA HARENGUS; MEMBRAS; MUSTELA; MUSTELA VISON; OSMERUS; OSMERUS EPERLANUS;

EID: 0037338965     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(02)00067-4     Document Type: Article

References (51)

1. Albro P.W., Parker C.E. Comparison of the composition of Aroclor 1242 and Aroclor 1016. J. Chromatogr. 169:1979;161-166.
2. Azais V., Arand M., Rauch P., Schramm H., Bellenand P., Narbonne J.F., Oesch F., Pascal G., Robertson L.W. A time-course investigation of vitamin A levels and drug metabolizing enzyme activities in rats following a single treatment with prototypic polychlorinated biphenyls and DDT. Toxicology. 44:1987;341-354.
3. Bank P.A., Cullum M.E., Jensen R.K., Zile M.H. Effect of hexachlorobiphenyl on vitamin A homeostasis in the rat. Biochim. Biophys. Acta. 25:1989;306-314.
4. Bhat P.V. Tissue concentrations of retinol, retinyl esters, and retinoic acid in vitamin A deficient rats administered a single dose of radioactive retinol. Can. J. Physiol. Pharmacol. 75:1997;74-77.
5. Blaner W.S., Olson J.A. Retinol and retinoic acid metabolism. Sporn M.B., Roberts A.B., Goodman D.S. The Retinoids Biology, Chemistry and Medicine . 1994;229-255 Raven Press, New York.
6. Blomhoff R., Green M.H., Balmer-Green J., Berg T., Norum K.R. Vitamin A metabolism new perspectives on absorption, transport and storage . Physiol. Rew. 71:1991;751-990.
7. Blomhoff R., Green M.H., Berg T., Norum K.R. Transport and storage of vitamin A. Science. 250:1990;399-404.
8. Brouwer A., Håkansson H., Kukler A., Van den Berg K.J., Ahlborg U.G. Marked alterations in retinoid homeostasis of Sprague-Dawley rats by a single i.p. dose of 10 micrograms/kg of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology. 58:1989;267-283.
9. Brouwer A., Klasson-Wehle E., Bokdam M., Morse D.C., Traag W.A. Competitive inhibition of thyroxin binding to transthyretin by monohydroxy metabolites of 3,4,3′,4′-tetrachlorobiphenyl. Chemosphere. 20:1990;1257-1262.
10. Brunström B., Håkansson H., Lundberg K. Effects of technical PCB preparation and fractions thereof on ethoxyresorufin-O-deethylase activity, vitamin A levels and thymic development in the mink (Mustela vison). Pharmacol. Toxicol. 69:1991;421-426.
11. Christensen E.I., Moskaug J.Ø., Vorum H., Jacobsen C., Gundersen T.E., Nykjær A., Blomhoff R., Willnow T.E., Moestrup S.K. Evidence for an essential role of megalin in transepithelial transport of retinol. J. Am. Soc. Nephrol. 10:1999;685-695.
12. Chu I., Poon R., Yagminas A., Lecavalier P., Håkansson H., Valli V.E., Kennedy S.W., Bergman A., Seegal R.F., Feeley M. Subchronic toxicity of PCB 105 (2,3,3′,4,4′-pentachlorobiphenyl) in rats. J. Appl. Toxicol. 18:1998;285-292.
13. Dew S.E., Ong D.E. Specificity of the retinol transporter of the rat small intestine brush border. Biochemistry. 33:1994;12340-12345.
14. Goodman D.S. Vitamin A metabolism. Arias I., Popper H., Schachter D., Schafritz D.A. The Liver Biology and Pathobiology . 1982;347-352 Raven Press, New York.
15. Håkansson H., Johansson L., Manzoor E., Ahlborg U.G. Effects of 2,3,7,8-tetrachlorobenzo-p-dioxin (TCDD) on the vitamin A status of Hartley guinea pigs, Sprague-Dawley rats, C57B1/6 mice, DBA/2 mice, and Golden Syrian hamsters. J. Nutr. Sci. Vitaminol. 37:1991;117-138.
16. Håkansson H., Manzoor E., Ahlborg U.G. Effects of technical PCB preparations and fractions thereof on vitamin A levels in the mink (Mustela vison). Ambio. 21:1992;588-590.
17. Heaton S.N., Bursian S.J., Giesy J.P., Tillitt D.E., Render J.A., Jones P.D., Verbrugge D.A., Kubiak T.J., Aulerich R.J. Dietary exposure of mink to carp from Saginaw Bay, Michigan. 1. Effects on reproduction and survival, and the potential risks to wild mink populations Arch. Environ. Contam. Toxicol. 28:1995;334-343.
18. Jurek M.A., Powers R.H., Gilbert L.G., Aust S.D. The effect of TCDD on acyl CoA retinol acyltransferase activity and vitamin A accumulation in the kidney of male Sprague-Dawley rats . J. Biochem. Toxicol. 5:1990;155-160.
19. Käkelä R., Hyvärinen H. Site-specific fatty acid composition in adipose tissues of several northern aquatic and terrestrial mammals. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 115:1996;501-514.
20. Käkelä R., Hyvärinen H. Composition of polyunsaturated fatty acids in the liver of freshwater and marine ringed seals (Phoca hispida ssp.) differs largely due to the diet of the seals. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 120:1998;231-237.
21. 2 (3,4-didehydroretinol) and E (α-tocopherol) in the liver and blubber of lacustrine and marine ringed seals (Phoca hispida sp.). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 116:1997;27-33.
22. 2, their fatty acyl esters, and vitamin E for biomonitoring mammals feeding on freshwater fish. Environ. Toxicol. Chem. 21:2002;390-396.
23. 2 in hepatic tissue and subcellural fractions in mink feeding on fish-based diets and exposed to Aroclor 1242. Environ. Toxicol. Chem. 21:2002;397-403.
24. 2, and E in minks exposed to polychlorinated biphenyls (Aroclor 1242®) and copper, via diet based on freshwater or marine fish. Environ. Toxicol. Chem. 18:1999;2595-2599.
25. Käkelä R., Kinnunen S., Käkelä A., Hyvärinen H., Asikainen J. Fatty acids, lipids, and cytochrome P-450 mono-oxygenase in hepatic microsomes of minks fed fish-based diets and exposed to Aroclor 1242. J. Toxicol. Environ. Health A. 64:2001;101-120.
26. Kelley S.K., Nilsson C.B., Green M.H., Green J.B., Håkansson H. Mobilization of vitamin A stores in rats after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin a kinetic analysis . Toxicol. Sci. 55:2000;478-484.
27. Lans M.C., Spiertz C., Brouwer A., Koeman J.H. Different competition of thyroxine binding to transthyretin and thyroxine-binding globulin by hydroxy-PCBs, PCDDs and PCDFs. Eur. J. Pharmacol. 270:1994;129-136.
28. Livrea M.A., Tesoriere L., Bongiorno A., Pintaudi A.M., Ciaccio M., Riccio A. Contribution of vitamin A to the oxidation resistance of human low density lipoproteins. Free Radic. Biol. Med. 18:1995;401-409.
29. MacDonald P.N., Ong D.E. Binding specificities of cellural retinol-binding protein and cellural retinol-binding protein, type II. J. Biol. Chem. 262:1987;10550-10556.
30. Mazzaro L.M., Dunn J.L., Furr H.C., Clark R.M. Vitamin A plasma kinetics in northern fur seals (Callorhinus ursinus). Can. J. Zool. 73:1995;10-14.
31. Murk A.J., Leonards P.E.G., Van Hattum B., Luit R., Van der Weiden M.E.J., Smit M. Application of biomarkers for exposure and effect of polyhalogenated aromatic hydrocarbons in naturally exposed European otters (Lutra lutra). Environ. Toxicol. Phar. 6:1998;91-102.
32. Nagy N.E., Holven K.B., Roos N., Senoo H., Kojima N., Norum K.R., Blomhoff R. Storage of vitamin A in extrahepatic stellate cells in normal rats. J. Lipid. Res. 38:1997;645-658.
33. Narbonne J.F., Grolier P., Albrecht R., Azais V., Oesh F., Robertson L.W. A time course investigation of vitamin A level and lipid composition of the liver endoplasmic reticulum in rats following treatment with congeneric polychlorobiphenyls. Toxicology. 60:1990;253-261.
34. NATO/CCMS., 1988. International toxicity equivalency factors (I-TEF) - Method of risk assessment for complex mixtures of dioxins and related compounds. North Atlantic Treaty Organization/Committee on the Challenge of Modern Society, Report No. 176.
35. Nilsson C.B., Hoeberg P., Trossvik C., Azais-Braesco V., Blaner W.S., Fex G., Harrison E.H., Nau H., Schmidt C.K., van Bennekum A.M., Håkansson H. 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases serum and kidney retinoic acid levels and kidney retinol esterification in the rat. Toxicol. Appl. Pharmacol. 169:2000;121-131.
36. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:1979;351-358.
37. Palace V.P., Hill M.F., Farahmand F., Singal P.K. Mobilization of antioxidant vitamin pools and hemodynamic function after myocardial infarction. Circulation. 99:1999;121-126.
38. Pike R.L., Brown M.L. Nutrition, An Integrated Approach. third ed :1984;John Wiley and Sons, New York.
39. Raila J., Buchholz I., Aupperle H., Raila G., Schoon H.A., Schweigert F.J. The distribution of vitamin A and retinol-binding protein in the blood plasma, urine, liver and kidneys of carnivores. Vet. Res. 31:2000;541-551.
40. Repa J.J., Plum L.A., Tadikonda P.K., Clagett-Dame M. All-trans-3,4-didehydroretinoic acid equals all-trans retinoic acid in support of chick neuronal development. FASEB J. 10:1996;1078-1084.
41. Ross S.A., McCaffery P.J., Drager U.C., De Luca L.M. Retinoids in embryonal development. Physiol. Rev. 80:2000;1021-1054.
42. Schweigert F.J., Bok V. Vitamin A in blood plasma and urine of dogs is affected by the dietary level of vitamin A. Int. J. Vitam. Nutr. Res. 70:2000;84-91.
43. Schweigert F.J., Buchholz I. Vitamin A metabolism in carnivores with special reference to fur bearing animals. Scientifur. 19:1995;305-307.
44. 2. Science. 108:1948;417-419.
45. Sokal R.R., Rohlf F.J. Biometry. 1981;Freeman, San Francisco, CA.
46. Tanumihardjo S.A., Koellner P.G., Olson J.A. The modified relative-dose-response assay as an indicator of vitamin A status in a population of well-nourished American children. Am. J. Clin. Nutr. 52:1990;1064-1067.
47. Tesoriere L., D'Arpa D., Re R., Livrea M.A. Antioxidant reactions of all-trans retinol in phospholipid bilayers effect of oxygen partial pressure radical fluxes, and retinol concentration . Arch. Biochem. Biophys. 343:1997;13-18.
48. Tillitt D.E., Gale R.W., Meadows J.C., Zajicek J.L., Peterman P.H., Heaton S.N., Jones P.D., Bursian S.J., Kubiac T.J., Giesy J.P., Aulerich R.J. Dietary exposure of mink to carp from Saginaw Bay. 3. Characterization of dietary exposure to planar halogenated hydrocarbons, dioxin equivalents, and biomagnification. Environ. Sci. Technol. 30:1996;283-291.
49. Wei S., Episkopou V., Piantedosi R., Maeda S., Shimada K., Gottesman M.E., Blaner W.S. Studies on the metabolism of retinol and retinol-binding protein in transthyretin-deficient mice produced by homologous recombination. J. Biol. Chem. 270:1995;866-870.
50. Wolf G. Multiple functions of vitamin A. Physiol. Rev. 64:1984;873-937.
51. Zile M.H., Cullum M.E. The function of vitamin A current concepts . Proc. Soc. Exp. Biol. Med. 172:1983;139-152.