Monosomy 3 in uveal melanoma: Correlation with clinical and histologic predictors of survival

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 3, 2003, Pages 1008-1011

  Scholes, Andrea G M ^a   Damato, Bertil E ^a,c   Nunn, Janice ^a   Hiscott, Paul ^a   Grierson, Ian ^a   Field, John K ^a,b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b Roy Castle International Centre for Lung Cancer Research   (United Kingdom)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SCHIFF BASE;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL TYPE; CHROMOSOME 3; CILIARY BODY; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIOID CELL; FEMALE; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MELANOMA; METASTASIS; MICROSATELLITE MARKER; MONOSOMY; MORTALITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; TUMOR CELL; TUMOR VOLUME; UVEA TUMOR;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOMES, HUMAN, PAIR 3; DNA, NEOPLASM; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MELANOMA; MICROSATELLITE REPEATS; MIDDLE AGED; MONOSOMY; POLYMERASE CHAIN REACTION; SURVIVAL RATE; UVEAL NEOPLASMS;

EID: 0037336215     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0159     Document Type: Article

References (12)

1. Diener West M, Hawkins BS, Markowitz JA, Schachat AP. A review of mortality from choroidal melanoma. II. A meta-analysis of 5-year mortality rates following enucleation, 1966 through 1988. Arch Ophthalmol. 1992;110:245-250.
2. Seddon JM, Albert DM, Lavin PT, Robinson N. A prognostic factor study of disease-free interval and survival following enucleation for uveal melanoma. Arch Ophthalmol. 1983;101:1894-1899.
3. McLean IW, Foster WD, Zimmerman LE, Gamel JW. Modifications of Callender's classification of uveal melanoma at the Armed Forces Institute of Pathology. Am J Ophthalmol. 1983;96:502-509.
4. Folberg R, Rummelt V, Parys-Van Ginderdeuren R, et al. The prognostic value of tumor blood vessel morphology in primary uveal melanoma. Ophthalmology. 1993;100:1389-1398.
5. Makitie T, Summanen P, Tarkkanen A, Kivelä T. Microvascular loops and networks as prognostic indicators in choroidal and ciliary body melanomas. J. Natl Cancer Inst. 1999;91:359-367.
6. Prescher G, Bornfeld N, Hirche H, Horsthemke B, Jockel KH, Becher R. Prognostic implications of monosomy 3 in uveal melanoma. Lancet. 1996;347:1222-1225.
7. Sisley K, Rennie IG, Parsons MA, et al. Abnormalities of chromosomes 3 and 8 in posterior uveal melanoma correlate with prognosis. Genes Chromosomes Cancer. 1997;19:22-28.
8. White VA, Chambers JD, Courtright PD, Chang WY, Horsman DE. Correlation of cytogenetic abnormalities with the outcome of patients with uveal melanoma. Cancer. 1998;83:354-359.
9. Scholes AG, Liloglou T, Maloney P, et al. Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma. Invest Ophthalmol Vis Sci. 2001;42:2472-2477.
10. Altman DG. Practical Statistics for Medical Research. London: Chapman and Hall; 1991:351-358.
11. Tschentscher F, Prescher G, Horsman DE, et al. Partial deletions of the long and short arm of chromosome 3 point to two tumor suppressor genes in uveal melanoma. Cancer Res. 2001;61:3439-3442.
12. Rummelt V, Folberg R, Woolson RF, Hwang T, Pe'er J. Relation between the microcirculation architecture and the aggressive be havior of ciliary body melanomas. Ophthalmology. 1995;102:844-851.