The effect of growth hormone (GH) replacement therapy in adult patients with type 1 diabetes mellitus and GH deficiency

Clinical Endocrinology

Volumn 58, Issue 3, 2003, Pages 309-315

  Christ, E R ^a,b   Simpson, H L ^a   Breen, L ^a   Sonksen P H ^a   Russell Jones, D L ^a   Kohner, E M ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BODY COMPOSITION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EYE PHOTOGRAPHY; FEMALE; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; STANDARD; VALIDATION PROCESS;

ADULT; ANALYSIS OF VARIANCE; BLOOD GLUCOSE; BODY COMPOSITION; DIABETES MELLITUS, TYPE 1; FEMALE; GROWTH HORMONE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOPITUITARISM; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MALE; QUALITY OF LIFE;

EID: 0037335035     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2003.01714.x     Document Type: Article

References (30)

1. Acerini, C.L., Cheetham, T.D., Edge, J.A. & Dunger, D.B. (2000) Both insulin sensitivity and insulin clearance in children and young adults with type I (insulin-dependent) diabetes vary with growth hormone concentrations and with age. Diabetologia, 43, 61-68.
2. Amiel, S.A., Sherwin, R.S., Hintz, R.L., Gertner, J.M., Press, C.M. & Tamborlane, W.V. (1984) Effect of diabetes and its control on insulin-like growth factors in the young subject with type I diabetes. Diabetes, 33, 1175-1179.
3. Boni-Schnetzler, M., Schmid, C., Meier, P.J. & Froesch, E.R. (1991) Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. American Journal of Physiology, 260, E846-E851.
4. Carroll, P.V., Christ, E.R., Bengtsson, B.A., Carlsson, L., Christiansen, J.S., Clemmons, D., Hintz, R., Ho, K., Laron, Z., Sizonenko, P., Sonksen, P.H., Tanaka, T. & Thorne, M. (1998) Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee. Journal of Clinical Endocrinology and Metabolism, 83, 382-395.
5. Carroll, P.V., Littlewood, R., Weissberger, A.J., Bogalho, P., McGauley, G., Sonksen, P.H. & Russell-Jones, D.L. (1997) The effects of two doses of replacement growth hormone on the biochemical, body composition and psychological profiles of growth hormone-deficient adults. European Journal of Endocrinology, 137, 146-153.
6. Christ, E.R., Carroll, P.V., Albany, E., Umpleby, A.M., Lumb, J.P., Wierzbicki, A.S., Simpson, H.L., Sonksen, P.H. & Russell-Jones, D.L. (2001) Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus. Clinical Endocrinology, 55, 777-787.
7. Cranston, I., Lomas, J., Maran, A., Macdonald, I. & Amiel, S.A. (1994) Restoration of hypoglycaemia awareness in patients with long-duration insulin-dependent diabetes. Lancet, 344, 283-287.
8. Cryer, P.E. (1993) Hypoglycemia unawareness in IDDM. Diabetes Care, 16 (Suppl. 3), 40-47.
9. Dagogo-Jack, S., Rattarasarn, C. & Cryer, P.E. (1994) Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM. Diabetes, 43, 1426-1434.
10. DCCT (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. New England Journal of Medicine, 329, 977-986.
11. Dunger, D.B. & Cheetham, T.D. (1996) Growth hormone insulin-like growth factor I axis in insulin-dependent diabetes mellitus. Hormone Research, 46, 2-6.
12. Dupuy, H.J. (1984) The psychological general well-being (PGWB) index. In Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies (ed. N.K. Wenger), pp. 170-183. Le Jacq, New York.
13. Edelman, S.V. (1998) Importance of glucose control. Medical Clinics of North America, 82, 665-687.
14. Edge, J.A., Dunger, D.B., Matthews, D.R., Gilbert, J.P. & Smith, C.P. (1990) Increased overnight growth hormone concentrations in diabetic compared with normal adolescents. Journal of Clinical Endocrinology and Metabolism, 71, 1356-1362.
15. Falholt, K., Jensen, I., Lindkaer Jensen, S., Mortensen, H., Volund, A., Heding, L.G., Noerskov Petersen, P. & Falholt, W. (1988) Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients. Diabetic Medicine, 5, 27-31.
16. Festa, A., D'Agostino, R. Jr, Mykkanen, L., Tracy, R.P., Zaccaro, D.J., Hales, C.N. & Haffner, S.M. (1999) Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS). Arteriosclerosis, Thrombosis, and Vascular Biology, 19, 562-568.
17. Hanaire-Broutin, H., Sallerin-Craute, B., Poncet, M.F.T.M., Bastide, R. & Rosenfeld, R.T. (1996) Insulin therapy and GH-IGF-I axis disorders in diabetes: impact of glycaemic control and hepatic insulinisation. Diabetes and Metabolism, 22, 245-250.
18. Hunt, S.M., McKenna, S.P. & Williams, J. (1981) Reliability of a population survey tool for measuring perceived health problems: a study of patients with osteoarthrosis. Journal of Epidemiology and Community Health, 35, 297-300.
19. Jacobson, A.M., de Groot, M. & Samson, J.A. (1994) The evaluation of two measures of quality of life in patients with type I and type II diabetes. Diabetes Care, 17, 267-274.
20. Kohner, E.M., Dollery, C.T., Fraser, T.R. & Bulpitt, C.J. (1970) Effect of pituitary ablation on diabetic retinopathy studied by fluorescence angiography. Diabetes, 19, 703-714.
21. Laager, R., Ninnis, R. & Keller, U. (1993) Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans. Journal of Clinical Investigation, 92, 1903-1909.
22. Malmstrom, R., Packard, C.J., Watson, T.D., Rannikko, S., Caslake, M., Bedford, D., Stewart, P., Yki-Jarvinen, H., Shepherd, J. & Taskinen, M.R. (1997) Metabolic basis of hypotriglyceridemic effects of insulin in normal men. Arteriosclerosis, Thrombosis, and Vascular Biology, 17, 1454-1464.
23. McGauley, G.A., Cuneo, R.C., Salomon, F. & Sonksen, P.H. (1990) Psychological well-being before and after growth hormone treatment in adults with growth hormone deficiency. Hormone Research, 33, 52-54.
24. Moller, A., Rasmussen, L.M., Thuesen, L. & Christiansen, J.S. (1989) Impact of human growth hormone on plasma lipoprotein concentrations. Hormone and Metabolic Research, 21, 207-209.
25. Russell-Jones, D.L., Weissberger, A.J., Bowes, S.B., Kelly, J.M., Thomason, M., Umpleby, A.M., Jones, R.H. & Sonksen, P.H. (1993) Protein metabolism in growth hormone deficiency, and effects of growth hormone replacement therapy. Acta Endocrinologica (Copenhagen), 128 (Suppl. 2), 44-47.
26. Salomon, F., Cuneo, R.C., Hesp, R. & Sonksen, P.H. (1989) The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. New England Journal of Medicine, 321, 1797-1803.
27. Shalet, S.M., Toogood, A., Rahim, A. & Brennan, B. (1998) The diagnosis of growth hormone deficiency in children and adults. Endocrine Reviews, 19, 203-223.
28. Simpson, H.L., Umpleby, A.M. & Russell-Jones, D.L. (1998) Insulin-like growth factor-I and diabetes: a review. Growth Hormone and IGF Research, 8, 83-95.
29. Sonksen, P.H. & Christiansen, J.S. (1998) Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency. Growth Hormone Research Society. Growth Hormone and IGF Research, 8 (Suppl. B), 89-92.
30. Teale, J.D. & Marks, V. (1990) Inappropriately elevated plasma insulin-like growth factor II in relation to suppressed insulin-like growth factor I in the diagnosis of non-islet cell tumour hypoglycaemia. Clinical Endocrinology (Oxford), 33, 87-98.