On the integration of subthreshold inputs from Perforant Path and Schaffer Collaterals in hippocampal CA1 pyramidal neurons

Journal of Computational Neuroscience

Volumn 14, Issue 2, 2003, Pages 185-192

  Migliore, Michele ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CNR   (Italy)

Author keywords

CA1; Dendritic integration; IA; Ih; Modeling

Indexed keywords

NEURONS;

CA1; CA1 PYRAMIDAL NEURON; DENDRITIC INTEGRATION; DENDRITICS; IA; IH; MODELING; REALISTIC MODEL; SCHAFFER COLLATERALS; SUBTHRESHOLD;

INTEGRATION;

CATION;

ACTION POTENTIAL; ANATOMICAL VARIATION; ARTICLE; BRAIN REGION; CATION TRANSPORT; CELL DENSITY; CONTROLLED STUDY; DENDRITE; EXPERIMENTAL MODEL; EXPERIMENTAL TEST; HIPPOCAMPUS; IN VIVO STUDY; ION CURRENT; KINETICS; MODULATION; NERVE CELL EXCITABILITY; PERFORANT NERVE TRACT; POTASSIUM CURRENT; PREDICTION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SIMULATION; SOMATIC CELL; SYNAPTIC POTENTIAL; SYSTEM ANALYSIS;

EID: 0037334587     PISSN: 09295313     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021906818333     Document Type: Article

References (28)

1. Agmon-Snir H, Carr CE, Rinzel J (1998) The role of dendrites in auditory coincidence detection. Nature 393: 268-272.
2. Berger T, Larkum ME, Luscher HR (2001) High I(h) channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs. J. Neurophysiol. 85: 855-868.
3. Chrobak JJ, Buzsáki G (1998K) Gamma oscillations in the entorhinal cortex of the freely behaving rat. J. Neurosci. 18: 388-398.
4. Csicsvari J, Hirase H, Czurko A, Mamiya A, Buzsáki G (1999) Oscillatory coupling of hippocampal pyramidal cells and interneurons in the behaving rat. J. Neurosci. 19: 274-287.
5. 2+ signals from back-propagating action potentials in small oblique dendrites of CA1 pyramidal neurons, Soc. Neurosci. Abs., Vol. 31.
6. Fries P, Reynolds JH, Rorie AE, Desimone R (2001) Modulation of oscillatory neuronal synchronization by selective visual attention. Science 291: 1560-3563.
7. Gray CM, Konig P, Engel AK, Singer W (1989) Oscillatory responses in cat visual cortex exhibit inter-columnar synchronization which reflects global stimulus properties. Nature 338: 334-337.
8. Hines M, Carnevale T (1997) The NEURON simulation environment. Neural Comp. 9: 178-1209.
9. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387: 869-875.
10. Jaffe DB, Carnevale NT (1999) Passive normalization of synaptic integration influenced by dendritic architecture. J. Neurophysiol. 82: 3268-3285.
11. Johnston D, Amaral DG (1998) Hippocampus. In: GM Shepherd, ed. The Synaptic Organization of the Brain, 4th edn. Oxford Univ. Press, New York, pp. 417-458.
12. Johnston D, Hoffman DA, Magee JC, Poolos NP, Watanabe S, Colbert CM, Migliore M (2000) Dendritic potassium channels in hippocampal pyramidal neurons. J. Physiol. 525: 75-81.
13. + channels in layer 5 neocortical pyramidal neurones from young rats: Subtypes and gradients. J. Physiol. 525: 621-639.
14. Larkum ME, Zhu JJ, Sakmann B (2001) Dendritic mechanisms underlying the coupling of the dendritic with the axonal action potential initiation zone of adult rat layer 5 pyramidal neurons. J. Physiol. 533: 447-466.
15. Magee JC (1998) Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. J. Neurosci. 18: 7613-7624.
16. Magee JC (1999) Dendritic Ih normalizes temporal summation in hippocampal CA1 neurons. Nat Neurosci. 2: 508-514.
17. Magee JC, Cook E (2000) Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons. Nature Neurosci. 3: 895-903.
18. Megías M, Emri ZS, Freund TF, Gulyás AI (2001) Total number and distribution of inhibitory and excitatory synapses on hippocampal CA1 pyramidal cells. Neuroscience 102: 527-540.
19. + conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons. J. Comput. Neurosci. 7: 5-16.
20. Migliore M, Shepherd GM (2002) Emerging rules for the distributions of active dendritic conductances. Nature Rev. Neurosci. 3: 362-370.
21. Rall W (1964) Theoretical significance of dendritic trees for neuronal input-output relations. In: RF Reiss, ed. Neural Theory and Modeling. Stanford University Press, Palo Alto, CA, pp. 73-97.
22. Spruston N, Häusser M, Stuart G (1999) Dendritic integration. In: G Stuart, N Spruston, M Häusser, eds. Dendrites. Oxford University Press, New York, NY, pp. 231-260.
23. Stuart GJ, Häusser M (2001) Dendritic coincidence detection of EPSPs and action potentials. Nature Neurosci. 4: 63-71.
24. Treves A, Rolls ET (1994) Computational analysis of the role of the hippocampus in memory. Hippocampus 4: 374-391.
25. Urban NN, Barrionuevo G (1998) Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons. Proc. Natl. Acad. Sci. USA 95: 11450-11455.
26. Williams SR, Stuart GJ (2000) Site independence of EPSP time course is mediated by dendritic I(h) in neocortical pyramidal neurons. J. Neurophysiol 83: 3177-3182.
27. Yeckel MF, Berger TW (1998) Spatial distribution of potentiated synapses in hippocampus: Dependence on cellular mechanisms and network properties. J. Neurosci. 18: 438-450.
28. Yuste R (1997) Potassium channels: Dendritic shock absorbers. Nature 387: 851-853.