Olanzapine and clozapine but not haloperidol reverse subchronic phencyclidine-induced functional hyperactivity of N-methyl-D-aspartate receptors in pyramidal cells of the rat medial prefrontal cortex

Neuropharmacology

Volumn 44, Issue 4, 2003, Pages 462-472

  Ninan, I ^a,b   Jardemark, K E ^a   Wang, R Y ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

AMPA; Medial prefrontal cortex; NMDA; Olanzapine; Phencyclidine

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CLOZAPINE; HALOPERIDOL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROLEPTIC AGENT; OLANZAPINE; PHENCYCLIDINE;

AFTERHYPERPOLARIZATION; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HYPERACTIVITY; INTRACELLULAR RECORDING; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; VOLTAGE CLAMP;

EID: 0037333394     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(03)00033-9     Document Type: Article

References (43)

1. 2A receptor agonist DOB on NMDA-evoked responses in pyramidal neurons of the rat medial prefrontal cortex. European Journal of Neuroscience. 11:1999;2917-2934.
2. Arvanov V.L., Liang X., Schwartz J., Grossman S., Wang R.Y. Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro. Journal of Pharmacology and Experimental Therapeutics. 283:1997;226-234.
3. 2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate-receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro. Neuropsychopharmacology. 18:1998;197-209.
4. Arvanov V.L., Wang R.Y. Clozapine, but not haloperidol, prevents the functional hyperactivity of NMDA receptors in rat cortical neurons induced by subchronic administration of phencyclidine. Journal of Pharmacology and Experimental Therapeutics. 289:1999;1000-1006.
5. Berretta N., Jones R.S. Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex. Neuroscience. 75:1996;339-344.
6. Cosgrove J., Newell T.G. Recovery of neuropsychological functions during reduction in use of phencyclidine. Journal of Clinical Psychology. 47:1991;159-169.
7. Finkel A.S., Redman S.J. Optimal voltage clamping with single microelectrodes. Smith T.G., Lecar A., Redman S.J., Gage P.W. Voltage and Patch Clamping with Microelectrodes. 1985;95-120 Williams & Wilkins, Baltimore.
8. Goldman-Rakic P.S. Working memory dysfunction in schizophrenia. Journal of Neuropsychiatry and Clinical Neuroscience. 6:1994;348-357.
9. Halliwell J.V., Adams P.R. Voltage-clamp analysis of muscarinic excitation in hippocampal neurons. Brain Research. 250:1982;71-92.
10. Hess G., Kuhnt U., Voronin L.L. Quantal analysis of paired-pulse facilitation in guinea pig hippocampal slices. Neuroscience Letters. 77:1987;187-192.
11. Holmes K., Keele B., Arvanov V., Shinnick-Gallagher P. Metabotropic glutamate receptor agonist-induced hyperpolarization in rat basolateral amygdala neurons: receptor characterization, second messengers and ion channels. Journal of Neurophysiology. 76:1996;3059-3069.
12. Honey C.R., Miljkovic Z., MacDonald J.F. Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid. Neuroscience Letters. 61:1985;135-139.
13. Honey G.D., Bullmore E.T., Soni W., Varatheesan M., Williams S.C.R., Sharma T. Differences in frontal cortical activation by a working memory task after substitution of risperidone for typical antipsychotic drugs in patients with schizophrenia. Proceedings of the National Academy of Sciences of the USA. 96:1999;13432-13437.
14. Jardemark K.E., Liang X., Arvanov V., Wang R.Y. Subchronic treatment with either clozapine, olanzapine or haloperidol produces a hyposensitive response of the rat cortical cells to N-methyl-D-aspartate. Neuroscience. 100:2000;1-9.
15. Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. American Journal of Psychiatry. 148:1991;1301-1308.
16. Jentsch J.D., Redmond D.E. Jr., Elsworth J.D., Taylor J.R., Youngren K.D., Roth R.H. Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. Science. 277:1997;953-955.
17. Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., Heninger G.R., Bowers M.B. Jr., Charney D.S. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Archives of General Psychiatry. 51:1994;199-214.
18. Lahti A.C., Weiler M.A., Tamara Michaelidis B.A., Parwani A., Tamminga C.A. Effects of ketamine in normal and schizophrenic volunteers. Neuropsychopharmacology. 25:2001;455-467.
19. Lupica C.R., Proctor W.R., Dunwiddie T.V. Presynaptic inhibition of excitatory synaptic transmission by adenosine in rat hippocampus: analysis of unitary EPSP variance measured by whole-cell recording. Journal of Neuroscience. 12:1992;3753-3764.
20. MacDonald J.F., Miljkovic Z., Pennefather P. Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. Journal of Neurophysiology. 58:1987;251-266.
21. Madison D.V., Lancaster B., Nicoll R.A. Voltage clamp analysis of cholinergic action in the hippocampus. Journal of Neuroscience. 7:1987;733-741.
22. Malhotra A.K., Adler C.M., Kennison S.D., Elman I., Pickar D., Breier A. Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine. Biological Psychiatry. 42:1997;664-668.
23. Malinow R., Tsien R.W. Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices. Nature. 346:1990;177-180.
24. Manabe T., Wyllie D.J., Perkel D.J., Nicoll R.A. Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus. Journal of Neurophysiology. 70:1993;1451-1459.
25. 3H]D-AP5, suggesting down-regulation of the cortical N-methy-D-aspartate receptors. Neuroscience. 30:1989;87-94.
26. McDonald J.W., Silverstein F.S., Johnston M.V. MK-801 pretreatment enhances N-methyl-D-aspartate-mediated brain injury and increases brain N-methyl-D-aspartate recognition site binding in rats. Neuroscience. 38:1990;103-113.
27. Noda Y., Kamei H., Mamiya T., Furukawa H., Nabeshima T. Repeated phencyclidine treatment induces negative symptom-like behavior in forced swimming test in mice: imbalance of prefrontal serotonergic and dopaminergic functions. Neuropsychopharmacology. 23:2000;375-387.
28. Nowicky A.V., Bindman L.J. The nitric oxide synthase inhibitor, N-monomethyl-L-arginine blocks induction of a long-term potentiation-like phenomenon in rat medial frontal cortical neurons in vitro. Journal of Neurophysiolology. 70:1993;1255-1259.
29. Qiao H., Noda Y., Kamei H., Nagai T., Furukawa H., Miura H., Kayukawa Y., Ohta T., Nabeshima T. Clozapine, but not haloperidol, reverses social behavior deficit in mice during withdrawal from chronic phencyclidine treatment. Neuroreport. 12:2001;11-15.
30. Quirion R., Bayorh M.A., Zerbe R.L., Pert C.B. Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain. Pharmacology Biochemistry Behavior. 17:1982;699-702.
31. Rainnie D.G., Holmes K.H., Shinnick-Gallagher P. Activation of postsynaptic metabotropic glutamate receptors by trans-ACPD hyperpolarizes neurons of the basolateral amygdala. Journal of Neuroscience. 14:1994;7208-7220.
32. Saransaari P., Lillrank S.M., Oja S.S. Phencyclidine treatment in mice: effects on phencyclidine binding sites and glutamate uptake in cerebral cortex preparations. Journal of Neural Transmission. 93:1993;47-59.
33. Schweitzer P., Madamba S., Champagnat J., Siggins G.R. Somatostatin inhibition of hippocampal CA1 pyramidal neurons: mediation by arachidonic acid and its metabolites. Journal of Neuroscience. 13:1993;2033-2049.
34. Swerdlow N.R., Bakshi V., Geyer M.A. Seroquel restores sensorimotor gating in phencyclidine-treated rats. Journal of Pharmacology and Experimental Therapeutics. 279:1996;1290-1299.
35. Wang C., McInnis J., Ross-Sanchez M., Shinnick-Gallagher P., Wiley J.L., Johnson K.M. Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia. Neuroscience. 107:2001;535-550.
36. Wang C., Showalter V.M., Hillman G.R., Johnson K.M. Chronic phencyclidine increases NMDA receptor NR1 subunit mRNA in rat forebrain. Journal of Neuroscience. 55:1999;762-769.
37. Wang R.Y., Liang X. M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice. Neuropsychopharmacology. 19:1998;74-85.
38. Wang R.Y., Liang X., Jardemark K.E., Arvanov V. Facilitation of NMDA transmission by olanzapine. Tran P.V., Bymaster F., Tye N., Herrera J., Breier A., Tollefson G. Olanzapine (Zyprexa) - A Novel Antipsychotic. 2000;114-131 Williams & Wilkins, Baltimore.
39. Williams K., Dichter M.A., Molinoff P.B. Up-regulation of N-methyl-D-aspartate receptors on cultured cortical neurons after exposure to antagonists. Molecular Pharmacology. 42:1992;147-151.
40. Wuarin J.P., Peacock W.J., Dubeck F.E. Single-electrode voltage clamp analysis of the N-methyl-D-aspartate component of synaptic responses in neocortical slices from children with intractable epilepsy. Journal of Neurophysiology. 67:1992;84-93.
41. Yang C.R., Seamans J.K., Gorelova N. Electrophysiological and morphological properties of layers V-VI principal pyramidal cells in rat prefrontal cortex in vitro. Journal of Neuroscience. 16:1996;1904-1921.
42. Yu B., Wang C., Liu J., Johnson K.M., Gallagher J.P. Adaptation to chronic PCP results in hyperfunctional NMDA and hypofunctional GABA(A) synaptic receptors. Neuroscience. 113:2002;1-10.
43. Zucker R.S. Short-term synaptic plasticity. Annual Review of Neuroscience. 12:1989;13-31.