메뉴 건너뛰기




Volumn 149, Issue 1, 2003, Pages 114-124

Characterisation of axon terminals in the rat dorsal horn that are immunoreactive for serotonin 5-HT3A receptor subunits

Author keywords

Confocal microscopy; Electron microscopy; Immunocytochemistry; Nociception; Primary afferent; Serotonin; Spinal cord

Indexed keywords

ANTIBODY; CALCITONIN GENE RELATED PEPTIDE; GLUTAMATE DECARBOXYLASE; LECTIN; NEUROTENSIN; RECEPTOR SUBUNIT; SEROTONIN 3 RECEPTOR;

EID: 0037333142     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-002-1339-7     Document Type: Article
Times cited : (32)

References (46)
  • 1
    • 0025925108 scopus 로고
    • Spinal 5-HT3 receptor-mediated antinociception: Possible release of GABA
    • Alhaider AA, Lei SZ, Wilcox GL (1991) Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA. J Neurosci 11:1881-1888
    • (1991) J Neurosci , vol.11 , pp. 1881-1888
    • Alhaider, A.A.1    Lei, S.Z.2    Wilcox, G.L.3
  • 2
    • 0029666041 scopus 로고    scopus 로고
    • The role of 5HT3 in nociceptive processing in the rat spinal cord: Results from behavioural and electrophysiological studies
    • Ali Z, Wu G, Kozlov A, Barasi S (1996) The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies. Neuroscience Lett 208:203-207
    • (1996) Neuroscience Lett , vol.208 , pp. 203-207
    • Ali, Z.1    Wu, G.2    Kozlov, A.3    Barasi, S.4
  • 3
    • 0027413319 scopus 로고
    • Ultrastructural morphology, synaptic relationships, and CGRP immunoreactivity of physiologically identified C-fiber terminals in the monkey spinal cord
    • Alvarez FJ, Kavookjian AM, Light AR (1993) Ultrastructural morphology, synaptic relationships, and CGRP immunoreactivity of physiologically identified C-fiber terminals in the monkey spinal cord. J Comp Neurol 329:472-490
    • (1993) J Comp Neurol , vol.329 , pp. 472-490
    • Alvarez, F.J.1    Kavookjian, A.M.2    Light, A.R.3
  • 4
    • 0029034576 scopus 로고
    • Immunocytochemical localisation of trkA receptors in chemically identified subgroups of adult rat sensory neurons
    • Averill S, McMahon SB, Clary DO, Reichardt LF, Priestley JV (1995) Immunocytochemical localisation of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur J Neurosci 7:1484-1494
    • (1995) Eur J Neurosci , vol.7 , pp. 1484-1494
    • Averill, S.1    McMahon, S.B.2    Clary, D.O.3    Reichardt, L.F.4    Priestley, J.V.5
  • 5
    • 0034193681 scopus 로고    scopus 로고
    • Serotonin receptor subtypes involved in the spinal antinociceptive effect of 5-HT in rats
    • Bardin L, Lavarenne J, Eschalier A (2000) Serotonin receptor subtypes involved in the spinal antinociceptive effect of 5-HT in rats. Pain 86:11-18
    • (2000) Pain , vol.86 , pp. 11-18
    • Bardin, L.1    Lavarenne, J.2    Eschalier, A.3
  • 7
    • 0024474475 scopus 로고
    • 5-HT3 receptors are membrane ion channels
    • Derkach V, Surprenant A, North RA (1989) 5-HT3 receptors are membrane ion channels. Nature 339:706-709
    • (1989) Nature , vol.339 , pp. 706-709
    • Derkach, V.1    Surprenant, A.2    North, R.A.3
  • 8
    • 0032761091 scopus 로고    scopus 로고
    • Immunolabeling of the rat central nervous system with antibodies partially selective of the short form of the 5-HT3 receptor
    • Doucet E, Miquel MC, Nosjean A, Vergé D, Hamon M, Emerit MB (2000) Immunolabeling of the rat central nervous system with antibodies partially selective of the short form of the 5-HT3 receptor. Neuroscience 95:881-892
    • (2000) Neuroscience , vol.95 , pp. 881-892
    • Doucet, E.1    Miquel, M.C.2    Nosjean, A.3    Vergé, D.4    Hamon, M.5    Emerit, M.B.6
  • 10
    • 0023823841 scopus 로고
    • Identification of 5-HT3 binding sites in rat spinal cord synaptosomal membranes
    • Glaum SR, Anderson EG (1988) Identification of 5-HT3 binding sites in rat spinal cord synaptosomal membranes. Eur J Pharmacol 156:287-290
    • (1988) Eur J Pharmacol , vol.156 , pp. 287-290
    • Glaum, S.R.1    Anderson, E.G.2
  • 11
    • 0023797069 scopus 로고
    • Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist
    • Glaum SR, Proudfit HK, Anderson EG (1988) Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist. Neurosci Lett 95:313-317
    • (1988) Neurosci Lett , vol.95 , pp. 313-317
    • Glaum, S.R.1    Proudfit, H.K.2    Anderson, E.G.3
  • 12
    • 0034672678 scopus 로고    scopus 로고
    • An excitatory role for 5-HT in spinal inflammatory nociceptive transmission; state-dependent actions via dorsal horn 5-HT3 receptors in the anaesthetized rat
    • Green GM, Scarth J, Dickenson A (2000) An excitatory role for 5-HT in spinal inflammatory nociceptive transmission; state-dependent actions via dorsal horn 5-HT3 receptors in the anaesthetized rat. Pain 89:81-88
    • (2000) Pain , vol.89 , pp. 81-88
    • Green, G.M.1    Scarth, J.2    Dickenson, A.3
  • 13
  • 14
    • 0033055195 scopus 로고    scopus 로고
    • Modulation of afferent-evoked neurotransmission by 5-HT3 receptors in young rat dorsal horn neurones in vitro: A putative mechanism of 5-HT3 induced anti-nociception
    • Khasabov SG, Lopez-Garcia JA, Asghar AUR, King AE (1999) Modulation of afferent-evoked neurotransmission by 5-HT3 receptors in young rat dorsal horn neurones in vitro: a putative mechanism of 5-HT3 induced anti-nociception. Brit J Pharmacol 127:843-852
    • (1999) Brit J Pharmacol , vol.127 , pp. 843-852
    • Khasabov, S.G.1    Lopez-Garcia, J.A.2    Asghar, A.U.R.3    King, A.E.4
  • 17
    • 0029005558 scopus 로고
    • Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord
    • Laporte AM, Fattaccini CM, Lombard MC, Chauveau J, Hamon M (1995) Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord. J Neural Transm 100:207-223
    • (1995) J Neural Transm , vol.100 , pp. 207-223
    • Laporte, A.M.1    Fattaccini, C.M.2    Lombard, M.C.3    Chauveau, J.4    Hamon, M.5
  • 18
    • 0030833052 scopus 로고    scopus 로고
    • Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig
    • Lawson SN, Crepps BA, Perl ER (1997) Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig. J Physiol (Lond) 505:177-191
    • (1997) J Physiol (Lond) , vol.505 , pp. 177-191
    • Lawson, S.N.1    Crepps, B.A.2    Perl, E.R.3
  • 19
    • 0036588468 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide immunoreactivity and afferent receptive properties of dorsal root ganglion neurones in guinea-pigs
    • Lawson SN, Crepps BA, Perl ER (2002) Calcitonin gene-related peptide immunoreactivity and afferent receptive properties of dorsal root ganglion neurones in guinea-pigs. J Physiol (Lond) 540:989-1002
    • (2002) J Physiol (Lond) , vol.540 , pp. 989-1002
    • Lawson, S.N.1    Crepps, B.A.2    Perl, E.R.3
  • 20
    • 0018770078 scopus 로고
    • Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers
    • Light AR, Perl ER (1979) Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol 186:133-150
    • (1979) J Comp Neurol , vol.186 , pp. 133-150
    • Light, A.R.1    Perl, E.R.2
  • 21
    • 0020570302 scopus 로고
    • Fine structure of serotonin containing axons in the marginal zone of the rat spinal cord
    • Maxwell DJ, Leranth C, Verhofstad AAJ (1983) Fine structure of serotonin containing axons in the marginal zone of the rat spinal cord. Brain Res 266:253-259
    • (1983) Brain Res , vol.266 , pp. 253-259
    • Maxwell, D.J.1    Leranth, C.2    Verhofstad, A.A.J.3
  • 22
    • 0030601695 scopus 로고    scopus 로고
    • A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: Co-localization with glutamate decarboxylase and neuropeptides
    • Maxwell L, Maxwell DJ, Neilson M, Kerr R (1996) A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: co-localization with glutamate decarboxylase and neuropeptides. Neuroscience 75:471-480
    • (1996) Neuroscience , vol.75 , pp. 471-480
    • Maxwell, L.1    Maxwell, D.J.2    Neilson, M.3    Kerr, R.4
  • 23
    • 0026522731 scopus 로고
    • Immunocytochemical staining of neuropeptides in terminal arborization of primary afferent fibers anterogradely labeled and identified at light and electron microscopic levels
    • Merighi A, Cruz F, Coimbra A (1992) Immunocytochemical staining of neuropeptides in terminal arborization of primary afferent fibers anterogradely labeled and identified at light and electron microscopic levels. J Neurosci Methods 42:105-113
    • (1992) J Neurosci Methods , vol.42 , pp. 105-113
    • Merighi, A.1    Cruz, F.2    Coimbra, A.3
  • 24
    • 0030612043 scopus 로고    scopus 로고
    • The 5-HT3 receptor is present in different subpopulations of GABAergic neurons in the rat telencephalon
    • Morales M, Bloom FE (1997) The 5-HT3 receptor is present in different subpopulations of GABAergic neurons in the rat telencephalon. J Neurosci 17:3157-3167
    • (1997) J Neurosci , vol.17 , pp. 3157-3167
    • Morales, M.1    Bloom, F.E.2
  • 25
    • 0029926290 scopus 로고    scopus 로고
    • Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system
    • Morales M, Battenberg E, De Lecea L, Sanna PP, Bloom FE (1996a) Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system. Brain Res Mol Brain Res 36:251-260
    • (1996) Brain Res Mol Brain Res , vol.36 , pp. 251-260
    • Morales, M.1    Battenberg, E.2    De Lecea, L.3    Sanna, P.P.4    Bloom, F.E.5
  • 26
    • 0030603113 scopus 로고    scopus 로고
    • The type 3 serotonin receptor is expressed in a subpopulation of GABAergic neurons in the rat neocortex and hippocampus
    • Morales M, Battenberg E, De Lecea L, Bloom FE (1996b) The type 3 serotonin receptor is expressed in a subpopulation of GABAergic neurons in the rat neocortex and hippocampus. Brain Res 731:199-202
    • (1996) Brain Res , vol.731 , pp. 199-202
    • Morales, M.1    Battenberg, E.2    De Lecea, L.3    Bloom, F.E.4
  • 27
    • 0032556653 scopus 로고    scopus 로고
    • Distribution of neurons expressing immunoreactivity for the 5HT3 receptor subtype in the rat brain and spinal cord
    • Morales M, Battenberg E, Bloom FE (1998) Distribution of neurons expressing immunoreactivity for the 5HT3 receptor subtype in the rat brain and spinal cord. J Comp Neurol 402:385-401
    • (1998) J Comp Neurol , vol.402 , pp. 385-401
    • Morales, M.1    Battenberg, E.2    Bloom, F.E.3
  • 28
    • 0035903962 scopus 로고    scopus 로고
    • 5-HT3-receptor subunits A and B are co-expressed in neurons of the dorsal root ganglion
    • Morales M, McCollum N, Kirkness EF (2001) 5-HT3-receptor subunits A and B are co-expressed in neurons of the dorsal root ganglion. J Comp Neurol 438:163-172
    • (2001) J Comp Neurol , vol.438 , pp. 163-172
    • Morales, M.1    McCollum, N.2    Kirkness, E.F.3
  • 29
    • 0002728512 scopus 로고
    • The immunocytochemical demonstration of GABAergic Neurons- methods and application
    • Chan-Palay V, Palay SL (eds). Alan R. Liss, New York
    • Oertel WH, Mugnaini E, Schmechel DE, Tappaz M, Kopin IJ (1982) The immunocytochemical demonstration of GABAergic Neurons- methods and application. In: Chan-Palay V, Palay SL (eds) Cytochemical methods in neuroanatomy. Alan R. Liss, New York, pp 297-329
    • (1982) Cytochemical Methods in Neuroanatomy , pp. 297-329
    • Oertel, W.H.1    Mugnaini, E.2    Schmechel, D.E.3    Tappaz, M.4    Kopin, I.J.5
  • 30
    • 0029875333 scopus 로고    scopus 로고
    • The role of 5-HT3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats
    • Peng YB, Lin Q, Willis WD (1996) The role of 5-HT3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats. J Pharmacol Exp Ther 276:116-124
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 116-124
    • Peng, Y.B.1    Lin, Q.2    Willis, W.D.3
  • 31
    • 0034930383 scopus 로고    scopus 로고
    • GABAA and 5-HT3 receptors are involved in dorsal root reflexes: Possible role in periaqueductal gray descending inhibition
    • Peng YB, Wu J, Willis WD, Kenshalo DR (2001) GABAA and 5-HT3 receptors are involved in dorsal root reflexes: possible role in periaqueductal gray descending inhibition. J Neurophysiol 86:49-58
    • (2001) J Neurophysiol , vol.86 , pp. 49-58
    • Peng, Y.B.1    Wu, J.2    Willis, W.D.3    Kenshalo, D.R.4
  • 32
    • 0028788849 scopus 로고
    • Ultrastructural features of the colocalization of calcitonin gene-related peptide with substance P or somatostatin in the dorsal horn of the spinal cord
    • Ribeiro-da-Silva A (1995) Ultrastructural features of the colocalization of calcitonin gene-related peptide with substance P or somatostatin in the dorsal horn of the spinal cord. Can J Physiol Pharmacol 73:940-944
    • (1995) Can J Physiol Pharmacol , vol.73 , pp. 940-944
    • Ribeiro-Da-Silva, A.1
  • 33
    • 0019960661 scopus 로고
    • Two types of synaptic glomeruli and their distribution in laminae I-III of the rat spinal cord
    • Ribeiro-da-Silva A, Coimbra A (1982) Two types of synaptic glomeruli and their distribution in laminae I-III of the rat spinal cord. J Comp Neurol 209:176-186
    • (1982) J Comp Neurol , vol.209 , pp. 176-186
    • Ribeiro-Da-Silva, A.1    Coimbra, A.2
  • 34
    • 0024502932 scopus 로고
    • Morphological characterization of substance P-like immunoreactive glomeruli in the superficial dorsal horn of the rat spinal cord and trigeminal subnucleus caudalis: A quantitative study
    • Ribeiro-da-Silva A, Tagari P, Cuello AC (1989) Morphological characterization of substance P-like immunoreactive glomeruli in the superficial dorsal horn of the rat spinal cord and trigeminal subnucleus caudalis: a quantitative study. J Comp Neurol 281:497-515
    • (1989) J Comp Neurol , vol.281 , pp. 497-515
    • Ribeiro-Da-Silva, A.1    Tagari, P.2    Cuello, A.C.3
  • 35
    • 0025165445 scopus 로고
    • Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: Relation of lectin reactivity to peptide and enzyme markers
    • Silverman JD, Kruger L (1990) Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: relation of lectin reactivity to peptide and enzyme markers. J Neurocytol 19:789-801
    • (1990) J Neurocytol , vol.19 , pp. 789-801
    • Silverman, J.D.1    Kruger, L.2
  • 36
    • 0019464864 scopus 로고
    • Distribution of serotonin-immunoreactivity in the central nervoussystem of the rat- cell bodies and terminals
    • Steinbusch HWM (1981) Distribution of serotonin-immunoreactivity in the central nervoussystem of the rat- cell bodies and terminals. Neuroscience 6:557-618
    • (1981) Neuroscience , vol.6 , pp. 557-618
    • Steinbusch, H.W.M.1
  • 37
    • 0021078781 scopus 로고
    • Receptive fields and responses to ionophoretically applied noradrenaline and 5-hydroxytryptamine of units recorded in laminae I-III of cat dorsal horn
    • Todd AJ, Millar J (1983) Receptive fields and responses to ionophoretically applied noradrenaline and 5-hydroxytryptamine of units recorded in laminae I-III of cat dorsal horn. Brain Res 288:159-167
    • (1983) Brain Res , vol.288 , pp. 159-167
    • Todd, A.J.1    Millar, J.2
  • 38
    • 0027376797 scopus 로고
    • The localization of classical transmitters and neuropeptides within neurons in laminae I-III of the mammalian spinal dorsal horn
    • Todd AJ, Spike RC (1993) The localization of classical transmitters and neuropeptides within neurons in laminae I-III of the mammalian spinal dorsal horn. Prog Neurobiol 41:609-638
    • (1993) Prog Neurobiol , vol.41 , pp. 609-638
    • Todd, A.J.1    Spike, R.C.2
  • 39
    • 0028158178 scopus 로고
    • Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat
    • Todd AJ, Spike RC, Price RF, Neilson M (1994) Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat. J Neurosci 14:774-784
    • (1994) J Neurosci , vol.14 , pp. 774-784
    • Todd, A.J.1    Spike, R.C.2    Price, R.F.3    Neilson, M.4
  • 40
    • 0025121225 scopus 로고
    • Pharmacological characterization of 5-hydroxytryptamine2 and 5- hydroxytryptamine3 receptors in rat dorsal root ganglion cells
    • Todorovic SM, Anderson EG (1990) Pharmacological characterization of 5-hydroxytryptamine2 and 5- hydroxytryptamine3 receptors in rat dorsal root ganglion cells. J Pharmacol Exp Ther 254:109-115
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 109-115
    • Todorovic, S.M.1    Anderson, E.G.2
  • 41
    • 0030929014 scopus 로고    scopus 로고
    • Cationic modulation of 5-HT2 and 5-HT3 receptors in rat sensory neurons: The role of K+, Ca2+ and Mg2+
    • Todorovic SM, Scroggs RS, Anderson EG (1997) Cationic modulation of 5-HT2 and 5-HT3 receptors in rat sensory neurons: the role of K+, Ca2+ and Mg2+. Brain Res 765:291-300
    • (1997) Brain Res , vol.765 , pp. 291-300
    • Todorovic, S.M.1    Scroggs, R.S.2    Anderson, E.G.3
  • 42
    • 0033539007 scopus 로고    scopus 로고
    • Enkephalinergic neurons express 5-HT3 receptors in the spinal cord dorsal horn: Single cell RT-PCR analysis
    • Tsuchiya M, Yamazaki H, Hori Y (1999) Enkephalinergic neurons express 5-HT3 receptors in the spinal cord dorsal horn: single cell RT-PCR analysis. Neuroreport 10:2749-2753
    • (1999) Neuroreport , vol.10 , pp. 2749-2753
    • Tsuchiya, M.1    Yamazaki, H.2    Hori, Y.3
  • 43
    • 0013844045 scopus 로고
    • Characteristics of excitatory and inhibitory synapses in the central nervous system of the cat
    • Uchizono K (1965) Characteristics of excitatory and inhibitory synapses in the central nervous system of the cat. Nature 209:642-643
    • (1965) Nature , vol.209 , pp. 642-643
    • Uchizono, K.1
  • 45
    • 0028240934 scopus 로고
    • Serotonin receptor subtypes in spinal antinociception in the rat
    • Xu W, Qiu XC, Han JS (1994) Serotonin receptor subtypes in spinal antinociception in the rat. J Pharmacol Exp Ther 269:1182-1189
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1182-1189
    • Xu, W.1    Qiu, X.C.2    Han, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.