메뉴 건너뛰기




Volumn 127, Issue 4, 1999, Pages 843-852

Modulation of afferent-evoked neurotransmission by 5-HT3 receptors in young rat dorsal horn neurones in vitro: A putative mechanism of 5-HT3 induced anti-nociception

Author keywords

5 HT3 receptor; Electrophysiology; Nociception; Sensory afferent; Serotonin receptor; Spinal cord

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; AZASETRON; BICUCULLINE; NALOXONE; OPIATE ANTAGONIST; SACLOFEN; SEROTONIN; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; TROPISETRON;

EID: 0033055195     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702592     Document Type: Article
Times cited : (44)

References (54)
  • 1
    • 0025925108 scopus 로고
    • 3 receptor-mediated antinociception: Possible release of GABA
    • 3 receptor-mediated antinociception: possible release of GABA. J. Neurosci., 11, 1881-1888.
    • (1991) J. Neurosci. , vol.11 , pp. 1881-1888
    • Alhaider, A.A.1    Lei, S.Z.2    Wilcox, G.L.3
  • 2
    • 0027372491 scopus 로고
    • B receptor sub-types in modulating spinal nociceptive transmission in mice
    • B receptor sub-types in modulating spinal nociceptive transmission in mice. J. Pharmacol., Exp. Ther., 265, 378-385.
    • (1993) J. Pharmacol., Exp. Ther. , vol.265 , pp. 378-385
    • Alhaider, A.A.1    Wilcox, G.L.2
  • 3
    • 0028171542 scopus 로고
    • 1 agonists and antagonists on nociceptive processing in the rat spinal cord: Results from behavioural and electrophysiological studies
    • 1 agonists and antagonists on nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies. Brain Res., 661, 83-90.
    • (1994) Brain Res. , vol.661 , pp. 83-90
    • Ali, Z.1    Wu, G.2    Kozlov, A.3    Barasi, S.4
  • 4
    • 0029666041 scopus 로고    scopus 로고
    • 3 in nociceptive processing in the rat spinal cord: Results from behavioural and electrophysiological studies
    • 3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies. Neurosci. Lett., 208, 203-207.
    • (1996) Neurosci. Lett. , vol.208 , pp. 203-207
    • Ali, Z.1    Wu, G.2    Kozlov, A.3    Barasi, S.4
  • 6
    • 0029867467 scopus 로고    scopus 로고
    • Mechanisms of allodynia: Interactions between sensitive mechanoreceptors and nociceptors
    • CERVERO, F. & LAIRD, J.M. (1996). Mechanisms of allodynia: interactions between sensitive mechanoreceptors and nociceptors. Neuro Report, 7, 526-528.
    • (1996) Neuro Report , vol.7 , pp. 526-528
    • Cervero, F.1    Laird, J.M.2
  • 7
    • 0026059773 scopus 로고
    • Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord
    • CRISP, T., STAFINSKY, J.L., SPANOS, L.J., URAM, M., PERNI, V.C. & DONEPUDI, H.B. (1991). Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord. Gen. Pharmacol., 22, 241-251.
    • (1991) Gen. Pharmacol. , vol.22 , pp. 241-251
    • Crisp, T.1    Stafinsky, J.L.2    Spanos, L.J.3    Uram, M.4    Perni, V.C.5    Donepudi, H.B.6
  • 8
    • 0001989283 scopus 로고
    • Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in cell bodies of brainstem neurons
    • DAHlSTROM, A. & FUXE, K. (1964). Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in cell bodies of brainstem neurons. Acta Physiol. Scand., 232, 1-55.
    • (1964) Acta Physiol. Scand. , vol.232 , pp. 1-55
    • Dahlstrom, A.1    Fuxe, K.2
  • 9
    • 0025607347 scopus 로고
    • 3 receptor subtypes modulate responses to noxious colorectal distension in the rat
    • 3 receptor subtypes modulate responses to noxious colorectal distension in the rat. Brain Res., 538, 64-75.
    • (1991) Brain Res. , vol.538 , pp. 64-75
    • Danzebrink, R.M.1    Gebhart, G.F.2
  • 10
    • 0019409123 scopus 로고
    • 5-Hydroxytryptamine reduces substance P responses on dorsal horn interneurones: A possible interaction of neurotransmitters
    • DAVIES, J.E. & ROBERTS, M.H. (1981). 5-Hydroxytryptamine reduces substance P responses on dorsal horn interneurones: a possible interaction of neurotransmitters, Brain Res., 217, 399-404.
    • (1981) Brain Res. , vol.217 , pp. 399-404
    • Davies, J.E.1    Roberts, M.H.2
  • 12
    • 73049143641 scopus 로고
    • Central inhibitory action attributable to presynaptic depolarization produced by muscle afferent volleys
    • ECCLES, J.R., ECCLES, R.M. & MAGNI, F. (1961). Central inhibitory action attributable to presynaptic depolarization produced by muscle afferent volleys. J. Physiol. (Lond.), 159, 147-166.
    • (1961) J. Physiol. (Lond.) , vol.159 , pp. 147-166
    • Eccles, J.R.1    Eccles, R.M.2    Magni, F.3
  • 14
    • 0025908176 scopus 로고
    • Analgesic profile of centrally administered 2-methylserotonin against acute pain in rats
    • GIORDANO, J. (1991). Analgesic profile of centrally administered 2-methylserotonin against acute pain in rats. Eur. J. Pharmacol., 199, 233-236.
    • (1991) Eur. J. Pharmacol. , vol.199 , pp. 233-236
    • Giordano, J.1
  • 15
    • 0031017369 scopus 로고    scopus 로고
    • Antinociceptive eflects of intrathecally administered 2-methylserotonin in developing rats
    • GIORDANO, J. (1997). Antinociceptive eflects of intrathecally administered 2-methylserotonin in developing rats. Dev. Brain Res., 98, 142-144.
    • (1997) Dev. Brain Res. , vol.98 , pp. 142-144
    • Giordano, J.1
  • 18
    • 0025281003 scopus 로고
    • Serotonin receptors and the modulation of pain
    • ed. Besson, J.M. Elsevier Science Publisher B.V. (Biomedical Division)
    • HAMON, M., COLLIN, E., CHANTREL, D., DAVAL, G., VERGE, D. & BOURGOIN, S. (1990). Serotonin receptors and the modulation of pain. In Serotonin and Pain, ed. Besson, J.M. pp. 53-72. Elsevier Science Publisher B.V. (Biomedical Division).
    • (1990) Serotonin and Pain , pp. 53-72
    • Hamon, M.1    Collin, E.2    Chantrel, D.3    Daval, G.4    Verge, D.5    Bourgoin, S.6
  • 20
    • 0025316429 scopus 로고
    • An in vitro study of the effects of serotonin on frog primary afferent terminals
    • HOLOHEAN, A.M., HACKMAN, J.C. & DAVIDOFF, R.A. (1990), An in vitro study of the effects of serotonin on frog primary afferent terminals. Neurosci. Lett., 113, 175-180.
    • (1990) Neurosci. Lett. , vol.113 , pp. 175-180
    • Holohean, A.M.1    Hackman, J.C.2    Davidoff, R.A.3
  • 21
    • 0029584411 scopus 로고
    • Modulation of frog spinal cord interneuronal activity by activation of 5-HT3 receptors
    • HOLOHEAN, A.M., HACKMAN, J.C. & DAVIDOFF, R.A. (1995). Modulation of frog spinal cord interneuronal activity by activation of 5-HT3 receptors. Brain Res., 704, 184-190.
    • (1995) Brain Res. , vol.704 , pp. 184-190
    • Holohean, A.M.1    Hackman, J.C.2    Davidoff, R.A.3
  • 22
    • 0029929076 scopus 로고    scopus 로고
    • Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord
    • HORI, Y., ENDO, K. & TAKAHASHI, T. (1996). Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord. J. Physiol. (Lond.), 492, 867-876.
    • (1996) J. Physiol. (Lond.) , vol.492 , pp. 867-876
    • Hori, Y.1    Endo, K.2    Takahashi, T.3
  • 24
    • 0029001060 scopus 로고
    • Contacts between serotoninergic fibres and dorsal horn spinocerebellar tract neurons in the cat and rat: A confocal microscopic study
    • JANKOWSKA, E., MAXWELL, D.J., DOLK, S., KRUTKI, P., BELICHENKO, P.V. & DAHLSTROM, A. (1995). Contacts between serotoninergic fibres and dorsal horn spinocerebellar tract neurons in the cat and rat: a confocal microscopic study. Neuroscience, 67, 477-487.
    • (1995) Neuroscience , vol.67 , pp. 477-487
    • Jankowska, E.1    Maxwell, D.J.2    Dolk, S.3    Krutki, P.4    Belichenko, P.V.5    Dahlstrom, A.6
  • 25
    • 0029010943 scopus 로고
    • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology
    • JENKINSON, D.H., BARNARD, E.A., HOYER, D., HUMPHREY, P.P., LEFF, P. & SHANKLEY, N.P. (1995). International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology. Pharmacol Rev., 47, 255-266.
    • (1995) Pharmacol Rev. , vol.47 , pp. 255-266
    • Jenkinson, D.H.1    Barnard, E.A.2    Hoyer, D.3    Humphrey, P.P.4    Leff, P.5    Shankley, N.P.6
  • 26
    • 0032513569 scopus 로고    scopus 로고
    • Serotonin-induced population primary afferent depolarisation in vitro: The effects of neonatal capsaicin treatment
    • KHASABOV, S.G., LOPEZ-GARCIA, J.A. & KING, A.E. (1998). Serotonin-induced population primary afferent depolarisation in vitro: the effects of neonatal capsaicin treatment. Brain Res., 789, 339-342.
    • (1998) Brain Res. , vol.789 , pp. 339-342
    • Khasabov, S.G.1    Lopez-Garcia, J.A.2    King, A.E.3
  • 31
    • 0031848283 scopus 로고    scopus 로고
    • Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: Implications for somatosensory transmission
    • LOPEZ-GARCIA, J.A. (1998). Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: implications for somatosensory transmission. Eur. J. Neurosci., 10, 1341-1349.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1341-1349
    • Lopez-Garcia, J.A.1
  • 32
    • 0030248009 scopus 로고    scopus 로고
    • A novel methodology for simultaneous assessment of the effects of 5-hydroxytryptamine on primary afferent polarisation and synaptic transmission in rat dorsal horn neurones in vitro
    • LOPEZ-GARCIA, J.A. & KING, A.E. (1996a). A novel methodology for simultaneous assessment of the effects of 5-hydroxytryptamine on primary afferent polarisation and synaptic transmission in rat dorsal horn neurones in vitro. J. Neurosci. Meth., 68, 1-6.
    • (1996) J. Neurosci. Meth. , vol.68 , pp. 1-6
    • Lopez-Garcia, J.A.1    King, A.E.2
  • 33
    • 0029860371 scopus 로고    scopus 로고
    • Pre-and post-synaptic actions of 5-hydroxytryptamine in the rat lumbar dorsal horn in vitro: Implications for somatosensory transmission
    • LOPEZ-GARCIA, J.A. & KING, A.F. (1996b). Pre-and post-synaptic actions of 5-hydroxytryptamine in the rat lumbar dorsal horn in vitro: implications for somatosensory transmission. Eur. J. Neurosci., 8, 2188-2197.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 2188-2197
    • Lopez-Garcia, J.A.1    King, A.F.2
  • 34
    • 0030176284 scopus 로고    scopus 로고
    • Dual effect of serotonin on formalin-induced nociception in the rat spinal cord
    • OYAMA, T., UEDA, M., KURAISHI, Y., AKAIKE, A. & SATOH, M. (1996). Dual effect of serotonin on formalin-induced nociception in the rat spinal cord. Neurosci. Res., 25, 129-135.
    • (1996) Neurosci. Res. , vol.25 , pp. 129-135
    • Oyama, T.1    Ueda, M.2    Kuraishi, Y.3    Akaike, A.4    Satoh, M.5
  • 35
    • 0029875333 scopus 로고    scopus 로고
    • 3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats
    • 3 receptors in periaqueductal gray-induced inhibition of nociceptive dorsal horn neurons in rats. J. Pharmacol. Exp. Ther., 276, 116-124.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 116-124
    • Peng, Y.B.1    Lin, Q.2    Willis, W.D.3
  • 36
    • 0018929456 scopus 로고
    • The pharmacology of dorsal root potentials recorded from the isolated cord of the rat
    • PRESTON, P.R. & WALLIS, D.I. (1980). The pharmacology of dorsal root potentials recorded from the isolated cord of the rat. Br. J. Pharmacol., 11, 527-534.
    • (1980) Br. J. Pharmacol. , vol.11 , pp. 527-534
    • Preston, P.R.1    Wallis, D.I.2
  • 37
    • 0028349464 scopus 로고
    • Do dorsal root reflexes augment peripheral inflammation?
    • REES, H., SLUKA, K.A., WESTLUND, K.N. & WILLIS, W.D. (1994). Do dorsal root reflexes augment peripheral inflammation? NeuroReport, 5, 821-824.
    • (1994) Neuroreport , vol.5 , pp. 821-824
    • Rees, H.1    Sluka, K.A.2    Westlund, K.N.3    Willis, W.D.4
  • 38
    • 0021707631 scopus 로고
    • 5-Hydroxytryptamine and antinociception
    • ROBERTS, M.H.T. (1984). 5-Hydroxytryptamine and antinociception. Neoropharmacology, 23, 1529-1536.
    • (1984) Neoropharmacology , vol.23 , pp. 1529-1536
    • Roberts, M.H.T.1
  • 39
    • 0025922199 scopus 로고
    • Properties of 5-hydroxytryptamine3 receptor-gated currents in adult rat dorsal root ganglion neurones
    • ROBERTSON, B. & BEVAN, S. (1991). Properties of 5-hydroxytryptamine3 receptor-gated currents in adult rat dorsal root ganglion neurones. Br. J. Pharmacol., 102, 272-276.
    • (1991) Br. J. Pharmacol. , vol.102 , pp. 272-276
    • Robertson, B.1    Bevan, S.2
  • 40
    • 0026649674 scopus 로고
    • 3 receptor antagonists, ICS 205-930, MDL 72222, MDL 73147EF and MDL 72699
    • 3 receptor antagonists, ICS 205-930, MDL 72222, MDL 73147EF and MDL 72699. Neuropharmacology, 31, 553-560.
    • (1992) Neuropharmacology , vol.31 , pp. 553-560
    • Rodgers, R.J.1    Shepherd, J.K.2
  • 41
    • 0020352966 scopus 로고
    • Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat
    • RUDA, M.A., COFFIELD, J. & STEINBUSCH, H.W. (1982). Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat. J. Neurosci., 2, 1660-1671.
    • (1982) J. Neurosci. , vol.2 , pp. 1660-1671
    • Ruda, M.A.1    Coffield, J.2    Steinbusch, H.W.3
  • 42
    • 0028981480 scopus 로고
    • Role of A delta afferent fibers in modulation of primary afferent input to the adult rat spinal cord
    • SHIMIZU, T., YOSHIMURA, M., BABA, H., SHIMOJI, K. & HIGASHI, H. (1995), Role of A delta afferent fibers in modulation of primary afferent input to the adult rat spinal cord. Brain Res., 691, 92-98.
    • (1995) Brain Res. , vol.691 , pp. 92-98
    • Shimizu, T.1    Yoshimura, M.2    Baba, H.3    Shimoji, K.4    Higashi, H.5
  • 43
    • 0027304804 scopus 로고
    • Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn
    • SORKIN, L.S., MCADOO, D.J. & WILLIS, W.D. (1993). Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn. Brain Res., 618, 95-108.
    • (1993) Brain Res. , vol.618 , pp. 95-108
    • Sorkin, L.S.1    Mcadoo, D.J.2    Willis, W.D.3
  • 44
    • 0019464864 scopus 로고
    • Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals
    • STEINBUSCH, H.W. (1981). Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. Neuroscience, 6, 557-618.
    • (1981) Neuroscience , vol.6 , pp. 557-618
    • Steinbusch, H.W.1
  • 45
    • 0025354044 scopus 로고
    • Activity-dependent changes in rat ventral horn neurones in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a d-APV sensitive windup
    • THOMPSON, S.W.N., KING, A.E. & WOOLF, C.J. (1990). Activity-dependent changes in rat ventral horn neurones in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a d-APV sensitive windup. Eur. J. Neurosci., 2, 638-649.
    • (1990) Eur. J. Neurosci. , vol.2 , pp. 638-649
    • Thompson, S.W.N.1    King, A.E.2    Woolf, C.J.3
  • 46
    • 0025609852 scopus 로고
    • An electron microscope study of glycine-like immunoreactivity in laminae I-III of the spinal dorsal horn of the rat
    • TODD, A.J. (1990). An electron microscope study of glycine-like immunoreactivity in laminae I-III of the spinal dorsal horn of the rat. Neuroscience, 39, 387-394.
    • (1990) Neuroscience , vol.39 , pp. 387-394
    • Todd, A.J.1
  • 47
    • 0021078781 scopus 로고
    • Receptive fields and responses to iontophoretically applied noradrenaline and 5-hydroxytryptamine of units of laminae I-III of cat dorsal horn
    • TODD, A.J. & MILLAR, J. (1983). Receptive fields and responses to iontophoretically applied noradrenaline and 5-hydroxytryptamine of units of laminae I-III of cat dorsal horn. Brain Res., 288, 159-167.
    • (1983) Brain Res. , vol.288 , pp. 159-167
    • Todd, A.J.1    Millar, J.2
  • 48
    • 0019393654 scopus 로고
    • Monoamine release from cat spinal cord by somatic stimuli; an intrinsic modulatory system
    • TYCE, G.M. & YAKSH, T.L. (1981). Monoamine release from cat spinal cord by somatic stimuli; an intrinsic modulatory system. J. Physiol. (Lond.), 314, 513-529.
    • (1981) J. Physiol. (Lond.) , vol.314 , pp. 513-529
    • Tyce, G.M.1    Yaksh, T.L.2
  • 49
    • 0023810615 scopus 로고
    • Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids
    • WILCOX, G.L. (1988). Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids. Ann. N.Y. Acad. Sci., 525, 228-236.
    • (1988) Ann. N.Y. Acad. Sci. , vol.525 , pp. 228-236
    • Wilcox, G.L.1
  • 50
    • 0025325356 scopus 로고
    • Nociceptive and anti-nociceptive action of serotonin agonists administered intrathecally
    • ed. Besson, J.M. Amsterdam: Exerpta Medica
    • 3 Receptors and Pain, ed. Besson, J.M. pp. 205-206. Amsterdam: Exerpta Medica.
    • (1990) 3 Receptors and Pain , pp. 205-206
    • Wilcox, G.L.1    Alhaider, A.A.2
  • 51
    • 0028566597 scopus 로고
    • Spinal serotonin IA and IC/2 receptors mediate supraspinal mu opioid-induced analgesia
    • XU, W., CUI, X.C. & HAN, J.S. (1994a). Spinal serotonin IA and IC/2 receptors mediate supraspinal mu opioid-induced analgesia. Neuro Report: 5, 2665-2668.
    • (1994) Neuro Report , vol.5 , pp. 2665-2668
    • Xu, W.1    Cui, X.C.2    Han, J.S.3
  • 52
    • 0028240934 scopus 로고
    • Serotonin receptor subtypes in spinal antinociception in the rat
    • XU, W., QIU, X.C. & HAN, J.S. (1994b). Serotonin receptor subtypes in spinal antinociception in the rat. J. Pharmacol. Exp. Ther., 269, 1182-1189.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 1182-1189
    • Xu, W.1    Qiu, X.C.2    Han, J.S.3
  • 53
    • 0026615758 scopus 로고
    • 3 receptor-mediated currents, in dissociated frog sensory neurones by benzoxazine derivative, Y-25130
    • 3 receptor-mediated currents, in dissociated frog sensory neurones by benzoxazine derivative, Y-25130. Br. J. Pharmacol., 107, 853-857.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 853-857
    • Yakushiji, T.1    Akaike, N.2
  • 54
    • 0028167206 scopus 로고
    • 1A receptors mediate the effect of the bulbospinal serotonin system on spinal dorsal horn nociceptive neurons
    • 1A receptors mediate the effect of the bulbospinal serotonin system on spinal dorsal horn nociceptive neurons. Pharmacology, 48, 1-10.
    • (1994) Pharmacology , vol.48 , pp. 1-10
    • Zemlan, F.P.1    Murphy, A.Z.2    Behbehani, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.