Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance

Nitric Oxide - Biology and Chemistry

Volumn 8, Issue 1, 2003, Pages 59-64

  Konovalova, N P ^a   Goncharova, S A ^a   Volkova, L M ^a   Rajewskaya, T A ^a   Eremenko, L T ^a   Korolev, A M ^a  

^a INSTITUTE OF PROBLEMS OF CHEMICAL PHYSICS   (Russian Federation)

Author keywords

Adjuvant activity; Antitumor cytostatics; Drug resistance; Effectiveness of therapy; Nitric oxide donor

Indexed keywords

3,3 BIS(HYDROXYMETHYL)OXETANE; 3,3 BIS(NITROXYMETHYL)OXETANE; ANTIMETASTATIC AGENT; ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; HYDROXYL RADICAL; NITRIC OXIDE DONOR; OXETANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LIFESPAN; MALE; MELANOMA CELL; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ABDOMINAL NEOPLASMS; ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN NEOPLASMS; CISPLATIN; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ETHERS, CYCLIC; HUMANS; LEUKEMIA P388; MALE; MELANOMA, EXPERIMENTAL; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NITRIC OXIDE DONORS;

EID: 0037331438     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1089-8603(02)00142-8     Document Type: Article

References (20)

1. Wink D., Vodovoz J., Cook J., Krishna M., Kim S., Coffin D., DeGraff W., Deluca A., Liebmann J., Mitchell J. The role of nitric oxide chemistry in cancer treatment. Biochemistry. 63(7):1998;948-957.
2. Proscurjakov S., Konopljannikov A., Ivannikov A., Skvotcov B., Cib A. Nitric oxide and therapy of tumors. Russian Oncol. J. 3:2000;41-45.
3. Blackburn R.V., Galoforo S.S., Berns C.M., Motwani N.M., Corry P.M., Lee Y.J. Differential induction of cell death in human glioma cell lines by sodium nitroprusside. Cancer. 82(6):1998;1137-1145.
4. Sophina Z., Goldin A. Experimental evaluation of anticancer drugs in USSR and USA. 1980;Medicina, Moscow.
5. Brune B., von Knethen A., Sandau K.B. Nitric oxide (NO): an effector of apoptosis. Cell Death Differ. 6(10):1999;969-975.
6. Kim P.K., Zamora R., Petrosko P., Billar T.R. The regulatory role of nitric oxide in apoptosis. Int. Immunopharmacol. 1(8):2001;1421-1441.
7. Yabuki M., Tsutsui K., Horton A.A., Yoshioka T., Utsumi K. Caspase activation and cytochrome c release during HL-60 cell apoptosis induced by a nitric oxide donor. Free Radical Res. 32(6):2000;507-514.
8. Kolb I.P. Mechanisms involved in the pro- and anti- apoptotic role of NO in human leukemia. Leukemia. 14(9):2000;1685-1694.
9. Hibbs J.B., Taintor R.R., Vavrin Z., Rachlin E.M. Nitric oxide: a cytostatic activated macrophage effector molecula. Biochem. Biophys. Res. Commun. 157:1989;87-94.
10. Boje K.M., Lakhman S.S. Nitric oxide redox species exert differential permeability effect on the blood-brain barrier. Therapeutics. 293(2):2000;545-550.
11. Pipili-Synetos E., Papageorgiou A., Sakkoula E., Sotiropoulou G., Fotsis T. Inhibition of angiogenesis, tumor growth and metastasis by the NO-releasing vasodilatators, isosorbid mononitrate and dinitrate. Br. J. Pharmacol. 116:1995;1829-1834.
12. Wang H.H., McIntosh A.R., Hasinoff B.B., Rector E.S., Ahmed N., Nance D.M., Or F.W. B16 melanoma cell arrest in the mouse liver induces nitric oxide release and sinusoidal defense against metastasis. Cancer Res. 60(20):2000;5862-5869.
13. Powell J.A., Mohamed N., Kerr I.S., Mousa S.A. Antiangiogenesis efficacy of nitric oxide donors. J. Cell. Biochem. 80(1):2000;104-114.
14. Pipili-Synetos E., Sakkoula E. Br. J. Pharmacol. 111:1994;894-902.
15. Radomsky M.W., Moncada S. Biological role of nitric oxide in platelet function. Moncada S. Clinical Relevance of Nitric Oxide in the Cardiovascular System. 1991;45-56 Madrid, Edicomplet.
16. Xie K., Fidler I. Therapy of cancer metastasis by activation of the inducible nitric oxide synthase. Cancer Metastasis Rev. 17(1):1998;55-75.
17. Schröder C.P., Godwin A.K., O'Dwyer P.J., Tew K.D., Hamilton T.C., Ozols R.F. Glutathione and drug resistance. Cancer Invest. 14(1):1996;158-168.
18. Gulick A.M., Fahl W.E. Mammalian glutathione-S-transferase: regulation of an enzyme system to achieve chemotherapeutic efficacy. Pharmacol. Ther. 66:1995;237-257.
19. Calvert P., Yao K.S., Hamilton T.C., O'Dwyer P.J. Clinical studies of reversal of drug resistance based on glutathione. Chem. Biol. Interact. 111-112:1998;213-224.
20. Wong P.C., Eiserich J.P., Reddy S., Lopez C.L., Cross C.E., van der Vliet A. Inactivation of glutathione S-transferases by nitric oxide-derived oxidants: exploring a role for tyrosine nitration. Arch. Biochem. Biophys. 394(2):2001;216-228.