A peptide (P2) derived from the variable heavy chain of an anti-P-selectin monoclonal antibody (LYP20) inhibits leucocyte adhesion to thrombin-activated platelets and endothelial cells

British Journal of Haematology

Volumn 120, Issue 4, 2003, Pages 605-610

  Murphy, Joseph F ^a,b   McGregor, John L ^a  

^a UNIVERSITÉ LYON 1   (France)

^b NONE   (Ireland)

Author keywords

Endothelial cell; Leucocyte; P selectin; Peptide; Platelet

Indexed keywords

ARGINYLLEUCYLLEUCYLVALYLARGINYLLEUCYLGLUTAMINYLTHREONYLLEUCYLCYSTEINYLARGIN YLASPARAGINYLISOLEUCYLISOLEUCYLTHREONYLARGININE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LYP20; PADGEM PROTEIN; PEPTIDE DERIVATIVE; THROMBIN; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL INTERACTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BINDING; THROMBOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; LEUKOCYTES; P-SELECTIN; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PLATELET ADHESIVENESS; THROMBIN;

EID: 0037330480     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04116.x     Document Type: Article

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