Horizontal monocular saccadic failure: An unusual clinically isolated syndrome progressing to multiple sclerosis

Multiple Sclerosis

Volumn 9, Issue 1, 2003, Pages 55-58

  Frohman, Elliot M ^a   Frohman, Teresa C ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Abducens palsy; Clinically isolated syndrome; Internuclear ophthalmoparesis

Indexed keywords

PREDNISONE;

ABDUCENS NERVE PARALYSIS; ADULT; ARTICLE; BRAIN INJURY; CASE REPORT; DEMYELINATING DISEASE; DIPLOPIA; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; FEMALE; FOLLOW UP; HUMAN; INTERNUCLEAR OPHTHALMOPLEGIA; MEDICAL ASSESSMENT; MULTIPLE SCLEROSIS; MYELITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; NYSTAGMUS; PONS ANGLE; SACCADIC EYE MOVEMENT; VISUAL ACUITY;

ABDUCENS NERVE DISEASES; ADULT; DISEASE PROGRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MULTIPLE SCLEROSIS; NYSTAGMUS, PATHOLOGIC; PONS; SACCADES; TEGMENTUM MESENCEPHALI;

EID: 0037330208     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1191/1352458503ms864oa     Document Type: Article

References (10)

1. Filippi M, Horsfield MA, Morrissey SP, MacManus DG, Rudge P, McDonald WI, Miller DH. Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. Neurology 1994; 44: 635 - 41.
2. Optic Neuritis Study Group. The 5-year risk of MS after optic neuritis: Experience of the Optic Neuritis Treatment Trial. Neurology 1997; 49: 1404 - 13.
3. Achiron A, Barak Y. Multiple sclerosis - From probably to definite diagnosis: A 7-year prospective study. Arch Neurol 2000; 57: 974 - 79.
4. Brex P, Ciccarelli O, O'Riordan JI, Sailer M, Thompson AI, Miller DH. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. N Engl J Med 2002; 346: 158 - 64.
5. Matthews WB. Clinical aspects. In Matthews WB ed. McAlpine's Multiple Sclerosis, Second Edition. Edinburgh: Churchill Livingstone, 1991: 43 - 298.
6. Frohman EM, Zhang H, Kramer PD, Fleckenstein J, Hawker K, Racke M, Frohman TC. MRI characteristics of the MLF in MS patients with chronic internuclear ophthalmoparesis. Neurology 2001; 57: 762 - 68.
7. Frohman EM, Zimmerman C, Frohman TC. Neuro-ophthalmic signs and symptoms in MS. In Burks J, Johnson K, eds. Multiple Sclerosis: Diagnosis, Medical Management, and Rehabilitation. New York: Demos, 2000: 341 - 75.
8. Zee DS. Internuclear ophthalmoplegia: Pathophysiology and diagnosis. Bailliere's Neurol 1992; 1: 455 - 70.
9. Jacobs LD, Beck RW, Simon JH, Kinkel RP, Brownscheidle CM, Murray TJ, Simonian NA, Slasor PJ, Sandrock AW, and the CHAMPS Study Group. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. N Engl J Med 2000; 343: 898 - 904.
10. Comi G, Filippi M, Barkhof F, Durelli L, Edan G, Fernandez O, Hartung H, Seeldrayers P, Sorensen PS, Rovaris M, Martinelli V, Hommes OR. Effect of early interferon treatment on conversion to definite multiple sclerosis: A randomized study. Lancet 2001; 357: 1576 - 82.