Specificity of human alcohol dehydrogenase 1C*2 (γ2γ2) for steroids and simulation of the uncompetitive inhibition of ethanol metabolism

Chemico-Biological Interactions

Volumn 143-144, Issue , 2003, Pages 183-193

  Plapp, Bryce V ^a   Berst, Kristine B ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Alcohol dehydrogenase; Alcohol metabolism; Fitsim; Inhibitors; Kinetics; Kinsim; Simulation; Steroids

Indexed keywords

3 BUTYLTHIOLANE 1 OXIDE; 3BETA HYDROXY 5ALPHA PREGNAN 20 ONE; 3BETA HYDROXY 5BETA ANDROSTAN 17 ONE; 3BETA HYDROXY 5BETA PREGNAN 20 ONE; 5BETA ANDROSTANOLONE; 5BETA CHOLANIC ACID 3 ONE; 5BETA PREGNAN 3,20 DIONE; ALCOHOL; ALCOHOL DEHYDROGENASE; ANDROSTANOLONE; CYCLOHEXANONE; ISOENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; STEROID; UNCLASSIFIED DRUG;

ALCOHOL METABOLISM; COMPARATIVE STUDY; COMPETITIVE INHIBITION; CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; PH; SIMULATION; STEROID BINDING; TEMPERATURE;

ALCOHOL DEHYDROGENASE; ENZYME INHIBITORS; ETHANOL; HUMANS; RECOMBINANT PROTEINS; STEROIDS; SUBSTRATE SPECIFICITY;

EQUUS CABALLUS;

EID: 0037327832     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00202-8     Document Type: Conference Paper

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