Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine

Psychopharmacology

Volumn 165, Issue 4, 2003, Pages 337-345

  Kozell, L B ^a   Meshul, C K ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Electron microscopy; Immunocytochemistry; Presynaptic; Sensitization; Vesicular

Indexed keywords

COCAINE; GLUTAMIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CELL DENSITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCOMOTION; MALE; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SENSITIZATION; VENTRAL TEGMENTUM;

EID: 0037323215     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1296-7     Document Type: Article

References (54)

1. Brog JS, Salyapongse A, Deutch AY, Zahm DS (1993) The patterns of afferent innervation of the core and shell in the "accumbens" part of the rat ventral striatum: immunohistochemical detection of retrogradely transported fluoro-gold. J Comp Neurol 338:255-278
2. Burrows KB, Meshul CK (1997) Methamphetamine alters presynaptic glutamate immunoreactivity in the caudate nucleus and motor cortex. Synapse 27:133-144
3. Burrows KB, Meshul CK (1999) High-dose methamphetamine treatment alters presynaptic GABA and glutamate immunoreactivity. Neuroscience 90:833-850
4. Cador M, Bjijou Y, Cailhol S, Stinus L (1999) D-amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience 94:705-721
5. Churchill L, Swanson CJ, Urbina M, Kalivas PW (1999) Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. J Neurochem 72:2397-2403
6. Fitzgerald LW, Ortiz J, Hamedani AG, Nestler EJ (1996) Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. J Neurosci 16:274-282
7. Ghasemzadeh MB, Nelson LC, Lu XY, Kalivas PW (1999) Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment. J Neurochem 72:157-165
8. Hepler JR, Toomim CS, McCarthy KD, Conti F, Battaglia G, Rustioni A, Petrusz P (1988) Characterization of antisera to glutamate and aspartate. J Histochem Cytochem 36:13-22
9. Kalivas PW, Alesdatter JE (1993) Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine. J Pharmacol Exp Ther 267:486-495
10. Kalivas PW, Duffy P (1993a) Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. J Neurosci 13:266-275
11. Kalivas PW, Duffy P (1993b) Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. J Neurosci 13:276-284
12. Kalivas PW, Duffy P (1995) D1 receptors modulate glutamate transmission in the ventral tegmental area. J Neurosci 15:5379-5388
13. Kalivas PW, Duffy P (1998) Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. J Neurochem 70:1497-1502
14. Kelley AE, Throne LC (1992) NMDA receptors mediate the behavioral effects of amphetamine infused into the nucleus accumbens. Brain Res Bull 29:247-254
15. Kozell LB, Meshul CK (2001) The effects of acute or repeated cocaine administration on nerve terminal glutamate within the rat mesolimbic system. Neuroscience 106:15-25
16. Li Y, Vartanian AJ, White FJ, Xue CJ, Wolf ME (1997) Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine. Psychopharmacology 134:266-276
17. Li Y, Hu XT, Berney TG, Vartanian AJ, Stine CD, Wolf ME, White FJ (1999) Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. Synapse 34:169-180
18. Li Y, White FC, Wolf ME (2000) Pharmacological reversal of behavioral and cellular indices of cocaine sensitization in the rat. Psychopharmacology 151:175-183
19. Loftis JM, Janowsky A (2000) Regulation of NMDA receptor subunits and nitric oxide synthase expression during cocaine withdrawal. J Neurochem 75:2040-2050
20. Meshul CK, Stallbaumer RK, Taylor B, Janowsky A (1994) Haloperidol-induced morphological changes in striatum are associated with glutamate synapses. Brain Res 648:181-195
21. Meshul CK, Stallbaumer RK, Allen C (1995) GM1 ganglioside administration partially counteracts the morphological changes associated with haloperidol treatment within the dorsal striatum of the rat. Psychopharmacology 121:461-469
22. Meshul CK, Buckman JF, Allen C, Riggan JP, Feller DJ (1996a) Activation of corticostriatal pathway leads to similar morphological changes observed following haloperidol treatment. Synapse 22:350-361
23. Meshul CK, Bunker GL, Mason JN, Allen C, Janowsky A (1996b) Effects of subchronic clozapine and haloperidol on striatal glutamatergic synapses. J Neurochem 67:1965-1973
24. Meshul CK, Noguchi K, Emre N, Ellison G (1998) Cocaine-induced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens. Synapse 30:211-220
25. Meshul CK, Emre N, Nakamura CM, Allen C, Donohue MK, Buckman JF (1999) Time-dependent changes in striatal glutamate synapses following a 6-hydroxydopamine lesion. Neuroscience 88:1-16
26. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, San Diego
27. Pettit HO, Pan HT, Parsons LH, Justice JB Jr (1990) Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. J Neurochem 55:798-804
28. Phend KD, Weinberg RJ, Rustioni A (1992) Techniques to optimise post-embedding single and double staining for amino acid neurotransmitters. J Histochem Cytochem 40:1011-1020
29. Pierce RC, Kalivas PW (1997) A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Res Brain Res Rev 25:192-216
30. Pierce RC, Bell K, Duffy P, Kalivas PW (1996) Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. J Neurosci 16:1550-1560
31. Pierce RC, Reeder DC, Hicks J, Morgan ZR, Kalivas PW (1998) Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine. Neuroscience 82:1103-1114
32. Pulvirenti L, Swerdlow NR, Koob GF (1989) Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats. Neurosci Lett 103:213-218
33. Pulvirenti L, Swerdlow NR, Koob GF (1991) Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine. Pharmacol Biochem Behav 40:841-845
34. Reid MS, Berger SP (1996) Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release. Neuroreport 7:1325-1329
35. Reid MS, Hsu K Jr, Berger SP (1997) Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse 27:95-105
36. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237:1219-1223
37. Sesack SR, Pickel VM (1990) In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spray neurons and are in apposition to each other. Brain Res 527:266-279
38. Sesack SR, Pickel VM (1992) Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J Comp Neurol 320:145-160
39. Sidiropoulous K, Chao S, Lu W, Wolf ME (2001) Amphetamine administration does not alter protein levels of the GLT-1 and EAAC1 glutamate transporter subtypes in rat midbrain, nucleus accumbens, striatum, or prefrontal cortex. Brain Res Mol Brain Res 90:187-192
40. Smith JA, Mo Q, Guo H, Kunko PM, Robinson SE (1995) Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. Brain Res 683:264-269
41. Tzschentke TM, Schmidt WJ (1998a) The development of cocaine-induced behavioral sensitization is affected by discrete quinolinic acid lesions of the prelimbic medial prefrontal cortex. Brain Res 795:71-76
42. Tzschentke TM, Schmidt WJ (1998b) Does the noncompetitive NMDA receptor antagonist dizocilpine (MK801) really block behavioral sensitization associated with repeated drug administration? Trends Pharmacol Sci 19:447-451
43. Tzschentke TM, Schmidt WJ (1999) Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization. Eur J Neurosci 11:4099-4109
44. Tzschentke TM, Schmidt WJ (2000) Differential effects of discrete subarea-specific lesions of the rat medial prefrontal cortex on amphetamine- and cocaine-induced behavioural sensitization. Cereb Cortex 10:488-498
45. Ungless MA, Whistler JL, Malenka RC, Bonci A (2001) Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature 411:583-587
46. Vezina P, Queen AL (2000) Induction of locomotor sensitization by amphetamine requires the activation of NMDA receptors in the rat ventral tegmental area. Psychopharmacology 151:184-191
47. Wolf ME, Khansa MR (1991) Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine. Brain Res 562:164-168
48. Wolf ME, Jeziorski M (1993) Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization. Brain Res 613:291-294
49. Wolf ME, Xue CJ (1998) Amphetamine and D1 dopamine receptor agonists produce biphasic effects on glutamate efflux in rat ventral tegmental area: modification by repeated amphetamine administration. J Neurochem 70:198-209
50. Wolf ME, Xue CJ (1999) Amphetamine-induced glutamate efflux in the rat ventral tegmental area is prevented by MK-801, SCH 23390, and ibotenic acid lesions of the prefrontal cortex. J Neurochem 73:1529-1538
51. Wolf ME, Dahlin SL, Hu XT, Xue CJ, White K (1995) Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: comparison with N-methyl-D-aspartate antagonists. Neuroscience 69:417-439
52. Xi ZX, Baker DA, Shen H, Carson DS, Kalivas PW (2002) Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens J Pharmacol Exp Ther 300:162-171
53. Xue CJ, Ng JP, Li Y, Wolf ME (1996) Acute and repeated systemic amphetamine administration: effects on extracellular glutamate, aspartate, and serine levels in rat ventral tegmental area and nucleus accumbens. J Neurochem 67:352-363
54. Zhang XF, Hu XT, White FJ, Wolf ME (1997) Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors. J Pharmacol Exp Ther 281:699-706