Induction of locomotor sensitization by amphetamine requires the activation of NMDA receptors in the rat ventral tegmental area

Psychopharmacology

Volumn 151, Issue 2-3, 2000, Pages 184-191

  Vezina, P ^a   Queen, A L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Amphetamine; AP 5; Excitatory amino acids; Locomotion; Locomotor sensitization; NMDA receptor; Nucleus accumbens; Psychomotor stimulant; Ventral tegmental area

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; AMPHETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG EFFECT; KINDLING; LOCOMOTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; SENSITIZATION; VENTRAL TEGMENTUM;

EID: 0033842281     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130000463     Document Type: Article

References (48)

1. 1 receptors in the ventral tegmental area in the behavioral sensitization induced by intraventral tegmental area injections of D-amphetamine
2. Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine
3. D-Amphetamine-induced behavioral sensitization: Implications of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation
4. MK-801 disrupts the expression but not the development of bromocriptine sensitization: A state-dependency interpretation
5. The regulation and modulation of pH in the nervous system
6. Excitatory amino acid projections to the nucleus accumbens septi in the rat: A retrograde transport study utilizing D[3H]aspartate and [3H]GABA
7. Motor effects following application of putative excitatory amino acid antagonists to the region of the mesencephalic dopamine cell bodies in the rat
8. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: Common adaptations among cross-sensitizing agents
9. Sensitization and individual differences to intraperitoneal amphetamine, cocaine or caffeine following repeated intracranial amphetamine infusions
10. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area
11. Amphetamine injected into the A10 dopamine region sensitizes rats to peripheral amphetamine and cocaine
12. Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine
13. 1 receptors modulate glutamate transmission in the ventral tegmental area
14. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area
15. Dopamine transmission in the initiation and expression of drug and stress-induced sensitization of motor activity
16. Blockade of 'reverse tolerance' to cocaine and amphetamine by MK-801
17. NMDA receptors mediate the behavioral effects of amphetamine infused into the nucleus accumbens
18. Metabotropic glutamate receptors are necessary for sensitization by amphetamine
19. Ibotenic acid lesions of prefrontal cortex do not prevent expression of behavioral sensitization to amphetamine
20. Can the 'state-dependency' hypothesis explain prevention of amphetamine sensitization in rats by NMDA receptor antagonists?
21. Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine
22. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations
23. The cellular framework for chemical signaling in the nucleus accumbens
24. The effects of intraventral tegmental area microinjection of glutamate receptor antagonists on locomotor activity
25. Role of dopaminergic mechanisms in the stimulatory effects of MK-801 injected into the ventral tegmental area and the nucleus accumbens
26. The response of non-dopamine neurons in substantia nigra and ventral tegmental area to amphetamine and apomorphine during hypermotility: The striatal influence
27. Amphetamine administered to the ventral tegmental area sensitizes rats to the locomotor effects of nucleus accumbens amphetamine
28. Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine
29. Sensitization to cocaine's motor activating properties produced by electrical kindling of the medial prefrontal cortex but not of the hippocampus
30. Electrophysiological characterization of GABAergic neurons in the ventral tegmental area
31. Development of both conditioning and sensitization of the behavioral activating effects of amphetamine is blocked by the non-competitive NMDA receptor antagonist MK-801
32. Microinjection of SCH-23390 into the ventral tegmental area and substantia nigra pars reticulata attenuate the development of sensitization to the locomotor effects of systemic amphetamine
33. Does the noncompetitive MNDA receptor antagonist dizocilpine (MK801) really block behavioural sensitization associated with repeated drug administration?
34. GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain
35. 1 dopamine receptor activation is necessary for the induction of sensitization by amphetamine in the ventral tegmental area
36. Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine - Lack of conditioned effects
37. Metabotropic glutamate receptors and the generation of locomotor activity: Interactions with midbrain dopamine
38. Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons
39. Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system
40. MK-801 (dizocilpine): Synergistic and conditioned stimulus in bromocriptine-induced psychomotor sensitization
41. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants
42. Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine
43. 1 dopamine receptor agonists produce biphasic effects on glutamate efflux in rat ventral tegmental area: Modification by repeated amphetamine administration
44. Effects of lesions of prefrontal cortex, amygdala or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-D-aspartate antagonists
45. Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors