Real-time quantitative PCR: Standardized detection of minimal residual disease in pediatric acute lymphoblastic leukemia

Journal of Pediatric Hematology/Oncology

Volumn 25, Issue 2, 2003, Pages 103-108

  Pine, Sharon R ^a   Moy, Fred H ^a   Wiemels, Joseph L ^b   Gill, Ramneet K ^a   Levendoglu Tugal, Oya ^a   Ozkaynak, Mehmet F ^a   Sandoval, Claudio ^a   Jayabose, Somasundaram ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Minimal residual disease; Pediatric acute lymphoblastic leukemia; Real time quantitative PCR

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; T LYMPHOCYTE RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DISEASE MARKER; FUSION GENE; GENE REARRANGEMENT; HUMAN; MINIMAL RESIDUAL DISEASE; MONITORING; POLYMERASE CHAIN REACTION; PRE B LYMPHOCYTE; PRIORITY JOURNAL;

CHILD; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA PRIMERS; DNA, NEOPLASM; FEMALE; GENES, T-CELL RECEPTOR; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; MALE; NEOPLASM, RESIDUAL; ONCOGENE PROTEINS, FUSION; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; TUMOR MARKERS, BIOLOGICAL;

EID: 0037318587     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-200302000-00004     Document Type: Article

References (18)

1. Pui CH. Acute lymphoblastic leukemia. Pediatr Clin North Am 1997;44:831-46.
2. Felix CA, Lange BJ, Chessells JM. Pediatric acute lymphoblastic leukemia: challenges and controversies in 2000. Hematology (Am Soc Hematol Educ Program) 2000;285-302.
3. Pui CH. Acute lymphoblastic leukemia in children. Curr Opin Oncol 2000;12:3-12.
4. Roberts WM, Estrov Z, Ouspenskaia MV, et al. Measurement of residual leukemia during remission in childhood acute lymphoblastic leukemia. N Engl J Med 1997;336:317-23.
5. Van Dongen JJM, Seriu T, Panzer-Grumayer ER, et al. Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood. Lancet 1998;352:1731-38.
6. Mayer SP, Giamelli J, Sandoval C, et al. Quantitation of leukemia clone-specific antigen gene rearrangements by a single-step PCR and fluorescence-based detection method. Leukemia 1999;13:1843-52.
7. Cayuela JM, Baruchel A, Orange C, et al. TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia. Blood 1996;88:302-8.
8. Cavé H, van der Werff ten Bosch J, Suciu S, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. N Engl J Med 1998;339:591-98.
9. Dibenedetto SP, Lo Nigro L, Mayer SP, et al. Detectable molecular residual disease at the beginning of maintenance therapy indicates poor outcome in children with T-cell acute lymphoblastic leukemia. Blood 1997;90:1226-32.
10. Eckert C, Biondi A, Seeger K, et al. Prognostic value of minimal residual disease in relapsed childhood acute lymphoblastic leukaemia. Lancet 2001;358:1239-41.
11. Kreuzer KA, Lass U, Bohn A, et al. LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Res 1999;59:3171-4.
12. Mensink E, van de Locht A, Schattenberg A, et al. Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR. Br J Haematol 1998;102:768-74.
13. Preudhomme C, Révillion F, Merlat A, et al. Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time' quantitative RT-PCR assay. Leukemia 1999;13:957-64.
14. Wittwer CT, Herrmann MG, Moss AA, et al. Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques 1997;22:130-8.
15. Nakao M, Janssen JWG, Flohr T, et al. Rapid and reliable quantification of minimal residual disease in acute lymphoblastic leukemia using rearranged immunoglobulin and T-cell receptor loci by LightCycler technology. Cancer Res 2000;60:3281-9.
16. Shurtleff SA, Buijs A, Behm FG, et al. TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia 1995;9:1985-9.
17. Wiemels JL, Alexander FE, Cazzaniga G, et al. Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer 2000;29:219-28.
18. Donovan JW, Ladetto M, Zou G, et al. Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia. Blood 2000;95:2651-8.