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Volumn 62, Issue 2, 2003, Pages 146-153

Mercapturate metabolism of 4-hydroxy-2-nonenal in rat and human cerebrum

Author keywords

4 hydroxy 2 nonenal (HNE); Alzheimer disease; Glutathione transferases; Lipid peroxidation; Mercapturic acid pathway

Indexed keywords

4 HYDROXYNONENAL; ACETYLCYSTEINE; AMYLOID BETA PROTEIN; GLUTATHIONE TRANSFERASE; POLYUNSATURATED FATTY ACID;

EID: 0037317983     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/62.2.146     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller JN, Pang Z, Geddes JW, Begley JG, Germeyer A, Waeg G, Mattson MP. Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: Role of the lipid peroxidation product 4-hydroxynonenal. J Neurochem 1997;69:273-84
    • (1997) J Neurochem , vol.69 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 2
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
    • Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J Neurochem 1997;68:255-64
    • (1997) J Neurochem , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 3
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark RJ, Pang Z, Geddes JW, Uchida K, Mattson MP. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation. J Neurosci 1997;17:1046-54
    • (1997) J Neurosci , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 5
    • 0031836724 scopus 로고    scopus 로고
    • Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype
    • Montine KS, Reich E, Neely MD, et al. Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype. J Neuropathol Exp Neurol 1998;57:415-25
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 415-425
    • Montine, K.S.1    Reich, E.2    Neely, M.D.3
  • 6
    • 0030989545 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
    • Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem 1997;68:2092-97
    • (1997) J Neurochem , vol.68 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 8
    • 0024509833 scopus 로고
    • Purification and properties of mouse stomach aldehyde dehydrogenase. Evidence for a role in the oxidation of peroxidic and aromatic aldehydes
    • Algar EM, Holmes RS. Purification and properties of mouse stomach aldehyde dehydrogenase. Evidence for a role in the oxidation of peroxidic and aromatic aldehydes. Biochim Biophys Acta 1989;995:168-73
    • (1989) Biochim Biophys Acta , vol.995 , pp. 168-173
    • Algar, E.M.1    Holmes, R.S.2
  • 9
    • 0024503296 scopus 로고
    • Oxidation of aldehydic products of lipid peroxidation by rat liver microsomal aldehyde dehydrogenase
    • Mitchell DY, Petersen DR. Oxidation of aldehydic products of lipid peroxidation by rat liver microsomal aldehyde dehydrogenase. Arch Biochem Biophys 1989;269:11-17
    • (1989) Arch Biochem Biophys , vol.269 , pp. 11-17
    • Mitchell, D.Y.1    Petersen, D.R.2
  • 11
    • 0032533744 scopus 로고    scopus 로고
    • Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity
    • Xie C, Lovell M, Markesbery WR. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radic Biol Med 1998;25:979-88
    • (1998) Free Radic Biol Med , vol.25 , pp. 979-988
    • Xie, C.1    Lovell, M.2    Markesbery, W.R.3
  • 12
    • 0036156332 scopus 로고    scopus 로고
    • Synthesis and cellular effects of an intracellularly activated analogue of 4-hydroxynonenal
    • Neely MD, Amarnath V, Weitlauf C, Montine TJ. Synthesis and cellular effects of an intracellularly activated analogue of 4-hydroxynonenal. Chem Res Toxicol 2002;15:40-47
    • (2002) Chem Res Toxicol , vol.15 , pp. 40-47
    • Neely, M.D.1    Amarnath, V.2    Weitlauf, C.3    Montine, T.J.4
  • 13
    • 0032799525 scopus 로고    scopus 로고
    • Determination of 4-hydroxy-2-nonenal at cellular levels by means of electrospray mass spectrometry
    • Gioacchini AM, Calonghi N, Boga C, et al. Determination of 4-hydroxy-2-nonenal at cellular levels by means of electrospray mass spectrometry. Rapid Commun Mass Spectrom 1999;13:1573-79
    • (1999) Rapid Commun Mass Spectrom , vol.13 , pp. 1573-1579
    • Gioacchini, A.M.1    Calonghi, N.2    Boga, C.3
  • 14
    • 0031772895 scopus 로고    scopus 로고
    • Identification of novel urinary metabolites of the lipid peroxidation product 4-hydroxy-2-nonenal in rats
    • Alary J, Debrauwer L, Fernanadez Y, et al. Identification of novel urinary metabolites of the lipid peroxidation product 4-hydroxy-2-nonenal in rats. Chem Res Toxicol 1998;11:1368-76
    • (1998) Chem Res Toxicol , vol.11 , pp. 1368-1376
    • Alary, J.1    Debrauwer, L.2    Fernanadez, Y.3
  • 15
    • 0028842190 scopus 로고
    • The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase
    • Hartley DP, Ruth JA, Petersen DR. The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase. Arch Biochem Biophys 1995;316:197-205
    • (1995) Arch Biochem Biophys , vol.316 , pp. 197-205
    • Hartley, D.P.1    Ruth, J.A.2    Petersen, D.R.3
  • 16
    • 0032033832 scopus 로고    scopus 로고
    • Consensus Report of the Working Group on: "Molecular and Biochemical Markers of Alzheimer's Disease"
    • The Ronald and Nancy Reagan Institute of the Alzheimer's Association and National Institute on Aging Working Group. Consensus Report of the Working Group on: "Molecular and Biochemical Markers of Alzheimer's Disease". Neurobiol Aging 1998;19:109-16
    • (1998) Neurobiol Aging , vol.19 , pp. 109-116
  • 17
    • 0003337638 scopus 로고    scopus 로고
    • Uptake and release of neurotransmitters
    • Crawley J, Gerfen C, McKay R, Rogawski M, Sibley D, Skolnick P, eds. New York: John Wiley and Sons
    • Janowsky A, Neve K, Eshleman A. Uptake and release of neurotransmitters. In: Crawley J, Gerfen C, McKay R, Rogawski M, Sibley D, Skolnick P, eds. Current protocols in neuroscience. New York: John Wiley and Sons, 1998
    • (1998) Current Protocols in Neuroscience
    • Janowsky, A.1    Neve, K.2    Eshleman, A.3
  • 18
    • 0034758150 scopus 로고    scopus 로고
    • Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cysteine conjugate impedes dopamine trafficking in vitro and in vivo
    • Sidell KR, Olson SJ, Ou JJ, Zhang Y, Amarnath V, Montine TJ. Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cysteine conjugate impedes dopamine trafficking in vitro and in vivo. J Neurochem 2001;79:510-21
    • (2001) J Neurochem , vol.79 , pp. 510-521
    • Sidell, K.R.1    Olson, S.J.2    Ou, J.J.3    Zhang, Y.4    Amarnath, V.5    Montine, T.J.6
  • 19
    • 0025853091 scopus 로고
    • Metabolism of 4-hydroxynonenal in hepatoma cell lines
    • Canuto RA, Muzio G, Bassi AM, et al. Metabolism of 4-hydroxynonenal in hepatoma cell lines. Adv Exp Med Biol 1991;284:75-84
    • (1991) Adv Exp Med Biol , vol.284 , pp. 75-84
    • Canuto, R.A.1    Muzio, G.2    Bassi, A.M.3
  • 20
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 21
    • 0028982312 scopus 로고
    • Glutathione S-transferases and gamma-glutamyl transpeptidase in the rat nervous system: A basis for differential susceptibility to neurotoxicants
    • Philbert MA, Beiswanger CM, Manson MM, et al. Glutathione S-transferases and gamma-glutamyl transpeptidase in the rat nervous system: A basis for differential susceptibility to neurotoxicants. Neurotoxicology 1995;16:349-62
    • (1995) Neurotoxicology , vol.16 , pp. 349-362
    • Philbert, M.A.1    Beiswanger, C.M.2    Manson, M.M.3
  • 22
    • 0026006754 scopus 로고
    • A pi form of glutathione-S-transferase is a myelin- and oligodendrocyte-associated enzyme in mouse brain
    • Tansey FA, Cammer W. A pi form of glutathione-S-transferase is a myelin- and oligodendrocyte-associated enzyme in mouse brain. J Neurochem 1991;57:95-102
    • (1991) J Neurochem , vol.57 , pp. 95-102
    • Tansey, F.A.1    Cammer, W.2
  • 23
    • 0034599916 scopus 로고    scopus 로고
    • Metabolism of 4-hydroxynonenal, a cytotoxic product of lipid peroxidation, in rat precision-cut liver slices
    • Laurent A, Perdu-Durand E, Alary J, Debrauwer L, Cravedi JP. Metabolism of 4-hydroxynonenal, a cytotoxic product of lipid peroxidation, in rat precision-cut liver slices. Toxicol Lett 2000;114:203-14
    • (2000) Toxicol Lett , vol.114 , pp. 203-214
    • Laurent, A.1    Perdu-Durand, E.2    Alary, J.3    Debrauwer, L.4    Cravedi, J.P.5
  • 24
    • 0025801691 scopus 로고
    • Immunohistologic localization of alpha, mu, and pi class glutathione-S-transferases in human tissues
    • Campbell JA, Corrigall AV, Guy A, Kirsch RE. Immunohistologic localization of alpha, mu, and pi class glutathione-S-transferases in human tissues. Cancer 1991;67:1608-13
    • (1991) Cancer , vol.67 , pp. 1608-1613
    • Campbell, J.A.1    Corrigall, A.V.2    Guy, A.3    Kirsch, R.E.4
  • 26
    • 0035917819 scopus 로고    scopus 로고
    • Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease
    • Aksenov MY, Markesbery WR. Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neurosci Lett 2001;302:141-45
    • (2001) Neurosci Lett , vol.302 , pp. 141-145
    • Aksenov, M.Y.1    Markesbery, W.R.2
  • 27
    • 0028292679 scopus 로고
    • Several closely related glutathione-S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues
    • Singhal SS, Zimniak P, Awasthi S, et al. Several closely related glutathione-S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch Biochem Biophys 1994;311:242-50
    • (1994) Arch Biochem Biophys , vol.311 , pp. 242-250
    • Singhal, S.S.1    Zimniak, P.2    Awasthi, S.3
  • 28
    • 0028265925 scopus 로고
    • A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues
    • Singhal SS, Zimniak P, Sharma R, Srivastava SK, Awasthi S, Awasthi YC. A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues. Biochim Biophys Acta 1994;1204:279-86
    • (1994) Biochim Biophys Acta , vol.1204 , pp. 279-286
    • Singhal, S.S.1    Zimniak, P.2    Sharma, R.3    Srivastava, S.K.4    Awasthi, S.5    Awasthi, Y.C.6
  • 29
    • 0033038758 scopus 로고    scopus 로고
    • Concise review of the glutathione S-transferases and their significance to toxicology
    • Eaton DL, Bammler TK. Concise review of the glutathione S-transferases and their significance to toxicology. Toxicol Sci 1999;49:156-64
    • (1999) Toxicol Sci , vol.49 , pp. 156-164
    • Eaton, D.L.1    Bammler, T.K.2
  • 30
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995;30:445-600
    • (1995) Crit Rev Biochem Mol Biol , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 31
    • 0035310710 scopus 로고    scopus 로고
    • Preferential detoxification of 4-hydroxy-2-nonenal enantiomers by hepatic glutathione S-tranferase isoforms in guinea pigs and rats
    • Hiratsuka A, Tobita K, Saito H, et al. Preferential detoxification of 4-hydroxy-2-nonenal enantiomers by hepatic glutathione S-tranferase isoforms in guinea pigs and rats. Biochem J 2001;355:237-44
    • (2001) Biochem J , vol.355 , pp. 237-244
    • Hiratsuka, A.1    Tobita, K.2    Saito, H.3
  • 32
    • 0032519517 scopus 로고    scopus 로고
    • Human glutathione transferase A4-4: An alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation
    • Hubatsch I, Ridderstrom M, Mannervik B. Human glutathione transferase A4-4: An alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem J 1998;330:175-79
    • (1998) Biochem J , vol.330 , pp. 175-179
    • Hubatsch, I.1    Ridderstrom, M.2    Mannervik, B.3
  • 33
    • 0027485154 scopus 로고
    • Human Mu-class glutathione S-transferases present in liver, skeletal muscle and testicular tissue
    • Hussey AJ, Hayes JD. Human Mu-class glutathione S-transferases present in liver, skeletal muscle and testicular tissue. Biochim Biophys Acta 1993;1203:131-41
    • (1993) Biochim Biophys Acta , vol.1203 , pp. 131-141
    • Hussey, A.J.1    Hayes, J.D.2
  • 34
    • 0031678044 scopus 로고    scopus 로고
    • Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease
    • Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease. Neurology 1998;51:1562-66
    • (1998) Neurology , vol.51 , pp. 1562-1566
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 35
    • 0033566083 scopus 로고    scopus 로고
    • The role of glutathione S-transferases hGSTAI-1 and hGSTA2-2 in protection against oxidative stress
    • Zhao T, Singhal SS, Piper JT, et al. The role of glutathione S-transferases hGSTAI-1 and hGSTA2-2 in protection against oxidative stress. Arch Biochem Biophys 1999;367:216-24
    • (1999) Arch Biochem Biophys , vol.367 , pp. 216-224
    • Zhao, T.1    Singhal, S.S.2    Piper, J.T.3


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