Progress in gene therapy of diabetes mellitus

Progress in Biochemistry and Biophysics

Volumn 30, Issue 1, 2003, Pages 24-26

  Li, Hong ^a   Su, Ben Li ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes mellitus; Gene therapy; Transfection

Indexed keywords

TRANSCRIPTION FACTOR PDX 1;

DIABETES MELLITUS; DRUG EFFECT; GENE THERAPY; HORMONE ACTION; IMMUNOLOGICAL TOLERANCE; IMMUNOTHERAPY; INSULIN RELEASE; KILLER CELL; NONHUMAN; PLASMID; REVIEW; TARGET CELL;

ARENA; SIA;

EID: 0037311610     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. Lee HC, Kim SJ, Kim K S, et al. Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue. Nature, 2000, 408 (6811): 483-488
2. Cheung A T, Dayanandan B, Lewis J T, et al. Glucose-dependent insulin release from genetically engineered K cells. Science, 2000, 290 (5498): 1959-1962
3. Yin D, Tang J G. Gene therapy for streptozotocin-induced diabetic mice by electroporational transfer of naked human insulin precursor DNA into skeletal muscle in vivo. FEBS Lett, 2001, 495 (1-2): 16-20
4. Raz I, Elias D, Avron A, et al. Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet, 2001, 24 (358): 1749-1753
5. Ferber S, Halkin A, Cohen H, et al. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat Med, 2000, 6 (5): 568-572