Human brain endothelial cells supply support for monocyte immunoregulatory functions

Journal of Neuroimmunology

Volumn 135, Issue 1-2, 2003, Pages 96-106

  Séguin, Rosanne ^a   Moditi, Zacharo ^a   Rotondo, Ronny ^a   Biernacki, Katarzyna ^a   Wosik, Karolina ^a   Prat, Alexandre ^a   Antel, Jack P ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

APC; Human brain derived endothelial cells; Transendothelial migration

Indexed keywords

BETA INTERFERON;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BRAIN CELL; CELL FUNCTION; CELL INFILTRATION; CELL INTERACTION; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; MEMBRANE; MONOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; ANTIGEN PRESENTATION; ASTROCYTES; BRAIN; CELL COMMUNICATION; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES; CYTOKINES; ENDOTHELIUM, VASCULAR; HUMANS; INTERFERON-BETA; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MONOCYTES; NERVE GROWTH FACTOR;

EID: 0037311543     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00431-9     Document Type: Article

References (28)

1. Bartholome E.J., Van A.I., Koyen E., Kiss R., Willems F., Goldman M., Opdenakker G. Human monocyte-derived dendritic cells produce bioactive gelatinase B: inhibition by IFN-beta. J. Interferon Cytokine Res. 21:2001;495-501.
2. Biernacki K., Prat A., Blain M., Antel J.P. Regulation of Th1 and Th2 lymphocyte migration by human adult brain endothelial cells. J. Neuropathol. Exp. Neurol. 60:2001;1127-1136.
3. Dorovini-Zis K., Prameya R., Bowman P.D. Culture and characterization of microvascular endothelial cells derived from human brain. Lab. Invest. 64:1991;425-436.
4. Floris S., Ruuls S.R., Wierinckx A., van der Pol S.M., Dopp E., van der Meide P.H., Dijkstra C.D., De Vries H.E. Interferon-beta directly influences monocyte infiltration into the central nervous system. J. Neuroimmunol. 127:2002;69-79.
5. Flugel A., Matsumuro K., Neumann H., Klinkert W.E., Birnbacher R., Lassmann H., Otten U., Wekerle H. Anti-inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: inhibition of monocyte transendothelial migration. Eur. J. Immunol. 31:2001;11-22.
6. Hickey W.F., Kimura H. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science. 239:1988;290-292.
7. Juedes A.E., Ruddle N.H. Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis. J. Immunol. 166:2001;5168-5175.
8. Karp C.L., Boxel-Dezaire A.H., Byrnes A.A., Nagelkerken L. Interferon-beta in multiple sclerosis: altering the balance of interleukin-12 and interleukin-10? Curr. Opin. Neurol. 14:2001;361-368.
9. Kuruganti P.A., Hinojoza J.R., Eaton M.J., Ehmann U.K., Sobel R.A. Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules - implications for multiple sclerosis. J. Neuropathol. Exp. Neurol. 61:2002;710-724.
10. La Sala A., Corinti S., Federici M., Saragovi H.U., Girolomoni G. Ligand activation of nerve growth factor receptor TrkA protects monocytes from apoptosis. J. Leukoc. Biol. 68:2000;104-110.
11. Lombard M.A., Wallace T.L., Kubicek M.F., Petzold G.L., Mitchell M.A., Hendges S.K., Wilks J.W. Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-alpha receptors in a human colon adenocarcinoma (Colo 205) cell line. Cancer Res. 58:1998;4001-4007.
12. McManus C.M., Liu J.S., Hahn M.T., Hua L.L., Brosnan C.F., Berman J.W., Lee S.C. Differential induction of chemokines in human microglia by type I and II interferons. Glia. 29:2000;273-280.
13. Neumann H., Misgeld T., Matsumuro K., Wekerle H. Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5779-5784.
14. Ozenci V., Kouwenhoven M., Teleshova N., Pashenkov M., Fredrikson S., Link H. Multiple sclerosis: pro- and anti-inflammatory cytokines and metalloproteinases are affected differentially by treatment with IFN-beta. J. Neuroimmunol. 108:2000;236-243.
15. Prat A., Al Asmi A., Duquette P., Antel J.P. Lymphocyte migration and multiple sclerosis: relation with disease course and therapy. Ann. Neurol. 46:1999;253-256.
16. Prat A., Biernacki K., Becher B., Antel J.P. B7 expression and antigen presentation by human brain endothelial cells: requirement for proinflammatory cytokines. J. Neuropathol. Exp. Neurol. 59:2000;129-136.
17. Prat A., Biernacki K., Pouly S., Nalbantoglu J., Couture R., Antel J.P. Kinin B1 receptor expression and function on human brain endothelial cells. J. Neuropathol. Exp. Neurol. 59:2000;896-906.
18. Prat A., Biernacki K., Wosik K., Antel J.P. Glial cell influence on the human blood-brain barrier. Glia. 36:2001;145-155.
19. Séguin, R., Biernacki, K., Rotondo, R.L., Prat, A., Antel, J. Regulation and functional effects of monocyte migration across human brain-derived endothelial cells. J. Neuropathol. Exp. Neurol., in press.
20. Stanimirovic D.B., Ball R., Durkin J.P. Evidence for the role of protein kinase C in astrocyte-induced proliferation of rat cerebromicrovascular endothelial cells. Neurosci. Lett. 197:1995;219-222.
21. Streit W.J. Microglia and macrophages in the developing CNS. Neurotoxicology. 22:2001;619-624.
22. Stuve O., Dooley N.P., Uhm J.H., Antel J.P., Francis G.S., Williams G., Yong V.W. Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9. Ann. Neurol. 40:1996;853-863.
23. Tao-Cheng J.H., Brightman M.W. Development of membrane interactions between brain endothelial cells and astrocytes in vitro. Int. J. Dev. Neurosci. 6:1988;25-37.
24. Tran E.H., Hoekstra K., Van Rooijen N., Dijkstra C.D., Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J. Immunol. 161:1998;3767-3775.
25. Ulvestad E., Williams K., Bo L., Trapp B., Antel J., Mork S. HLA class II molecules (HLA-DR, -DP, -DQ) on cells in the human CNS studied in situ and in vitro. Immunology. 82:1994;535-541.
26. Villoslada P., Hauser S.L., Bartke I., Unger J., Heald N., Rosenberg D., Cheung S.W., Mobley W.C., Fisher S., Genain C.P. Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system. J. Exp. Med. 191:2000;1799-1806.
27. Williams K.C., Dooley N.P., Ulvestad E., Waage A., Blain M., Yong V.W., Antel J.P. Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1. J. Neurosci. 15:1995;1869-1878.
28. Wosik K., Becher B., Ezman A., Nalbantoglu J., Antel J.P. Caspase 8 expression and signaling in Fas injury-resistant human fetal astrocytes. Glia. 33:2001;217-224.