What do eosinophils tell us in biopsies of patients with inflammatory bowel disease?

Journal of Clinical Gastroenterology

Volumn 36, Issue 2, 2003, Pages 93-98

  Yang, Guang Yu ^a   West, A Brian ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHRONIC DISEASE; CROHN DISEASE; EDITORIAL; ENTERITIS; EOSINOPHIL; GRANULOMA; HUMAN; INTESTINE BIOPSY; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; ULCERATIVE COLITIS;

BIOPSY; CHRONIC DISEASE; EOSINOPHILS; EVIDENCE-BASED MEDICINE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA;

EID: 0037310978     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004836-200302000-00001     Document Type: Editorial

References (46)

1. Weller PF. The immunobiology of eosinophils. N Engl J Med 1991;324:1110-8.
2. Gleich GJ, Adolphson CR, Leiferman KM. The biology of the eosinophilic leukocyte. Annu Rev Med 1993;44:85-101.
3. Walsh GM. Eosinophil granule proteins and their role in disease. Curr Opin Hematol 2001;8:28-33.
4. Rothenberg ME. Eosinophilia. N Engl J Med 1998;338:1592-600.
5. Carvalho ATP, Elia CCS, de Souza HSP, et al. Immunohistochemical study of intestinal eosinophils in inflammatory bowel disease. J Clin Gastroenterol 2003;36:120-5.
6. Jeziorska M, Haboubi N, Schofield P, et al. Distribution and activation of eosinophils in inflammatory bowel disease using an improved immunohistochemical technique. J Pathol 2001;194:484-92.
7. D'Arienzo A, Manguso F, Astarita C, et al. Allergy and mucosal eosinophil infiltrate in ulcerative colitis. Scand J Gastroenterol 2000;35:624-31.
8. Bischoff SC, Mayer J, Nguyen QT, et al. Immunohistologic assessment of intestinal eosinophil activation in patients with eosinophilic gastroenteritis and inflammatory bowel disease. Am J Gastroenterol 1999;94:3521-9.
9. Nishitani H, Okabayashi M, Satomi M, et al. Infiltration of peroxidase-producing eosinophils into the lamina propria of patients with ulcerative colitis. J Gastroenterol 1998;33:189-95.
10. Bischoff SC, Wedemeyer J, Herrmann A, et al. Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease. Histopathology 1996;28:1-13.
11. Oshitani N, Campbell A, Kitano A, et al. In situ comparison of phenotypical and functional activity of infiltrating cells in ulcerative colitis mucosa. J Pathol 1996;178:95-9.
12. Makiyama K, Kanzaki S, Yamasaki K, et al. Activation of eosinophils in the pathophysiology of ulcerative colitis. J Gastroenterol 1995;30(Suppl 8):64-9.
13. Dubucquoi S, Janin A, Klein O, et al. Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease. Gut 1995;37:242-6.
14. Raab Y, Sundberg C, Hallgren R, et al. Mucosal synthesis and release of prostaglandin E2 from activated eosinophils and macrophages in ulcerative colitis. Am J Gastroenterol 1995;90:614-20.
15. Walsh RE, Gaginella TS. The eosinophil in inflammatory bowel disease. Scand J Gastroenterol 1991;26:1217-24.
16. Choy MY, Walker-Smith JA, Williams CB, et al. Activated eosinophils in chronic inflammatory bowel disease. Lancet 1990;336:126-7.
17. Hallgren R, Colombel JF, Dahl R, et al. Neutrophil and eosinophil involvement of the small bowel in patients with celiac disease and Crohn's disease: studies on the secretion rate and immunohistochemical localization of granulocyte granule constituents. Am J Med 1989;86:56-64.
18. Sarin SK, Malhotra V, Sen Gupta S, et al. Significance of eosinophil and mast cell counts in rectal mucosa in ulcerative colitis. A prospective controlled study. Dig Dis Sci 1987;32:363-7.
19. Willoughby CP, Piris J, Truelove SC. Tissue eosinophils in ulcerative colitis. Scand J Gastroenterol 1979;14:395-9.
20. Anthonisen P, Riis P. Eosinophilic granulocytes in the rectal mucus of patients with ulcerative colitis and Crohn's disease of the ileum and colon. Scand J Gastroenterol 1971;6:731-4.
21. Rothenberg ME, Mishra A, Brandt EB, et al. Gastrointestinal eosinophils in health and disease. Adv Immunol 2001;78:291-328.
22. Rothenberg ME, Mishra A, Brandt EB, et al. Gastrointestinal eosinophils. Immunol Rev 2001;179:139-55.
23. Desreumaux P, Nutten S, Colombel JF. Activated eosinophils in inflammatory bowel disease: do they matter? Am J Gastroenterol 1999;94:3396-8.
24. Furuta GT, Ackerman SJ, Wershil BK. The role of the eosinophil in gastrointestinal diseases. Curr Opin Gastroenterol 1995;11:541-7.
25. Levy AM, Kita K. The eosinophil in gut inflammation: effector or director? Gastroenterol 1996;110:952-4.
26. Akin C, Metcalfe DD. Surrogate markers of disease in mastocytosis. Int Arch Allergy Immunol 2002;127:133-6.
27. Sangfelt P, Carlson M, Thorn M, et al. Neutrophil and eosinophil granule proteins as markers of response to local prednisolone treatment in distal ulcerative colitis and proctitis. Am J Gastroenterol 2001;96:1085-90.
28. Lamas AM, Leon OG, Schleimer RP. Glucocorticoids inhibit eosinophil response to granulocyte-macrophage colony-stimulating factor. J Immunol 1991;8:790-5.
29. Jahnsen FL, Brandtzaeg P, Halstensen TS. Monoclonal antibody EG2 does not provide reliable immunohistochemical discrimination between resting and activated eosinophils. J Immunol Method 1994;175:23-36.
30. Nakajima H, Loegering DA, Kita H. Reactivity of monoclonal antibodies EG1 and EG2 with eosinophils and their granule proteins. J Leukoc Biol 1999;66:447-457.
31. Winterkamp S, Raithel M, Hahn EG. Secretion and tissue content of eosinophil cationic protein in Crohn's disease. J Clin Gastroenterol 2000;30:170-5.
32. Saitoh O, Kojima K, Sugi K, et al. Fecal eosinophil granule-derived proteins reflect disease activity in inflammatory bowel disease. Am J Gastroenterol 1999;94:3513-20.
33. Carlson M, Raab Y, Peterson C, et al. Increased intraluminal release of eosinophil granule proteins EPO, ECP, EPX, and cytokines in ulcerative colitis and proctitis in segmental perfusion. Am J Gastroenterol 1999;94:1876-83.
34. Troncone R, Caputo N, Esposito V, et al. Increased concentrations of eosinophilic cationic protein in whole-gut lavage fluid from children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1999;28:164-8.
35. Dvorak AM. Ultrastructural evidence for release of major basic protein-containing crystalline cores of cosinophil granules in vivo: cytotoxic potential in Crohn's disease. J Immunol 1980;125:460-2.
36. Kato M, Kephart GM, Morikawa A, et al. Eosinophil infiltration and degranulation in normal human tissues: evidence for eosinophil degranulation in normal gastrointestinal tract. Int Arch Allergy Immunol 2001;125(Suppl):155-8.
37. Rankin SM, Conroy DM, Williams TJ. Eotaxin and eosinophil recruitment: implications for human disease. Mol Med Today 2000;6:20-7.
38. Elsner J, Kapp A. The chemokine network in eosinophil activation. Allergy Asthma Proc 2001;22:139-48.
39. Hans-Uwe Simon. Regulation of eosinophil and neutrophil apoptosis-similarities and differences. Immunol Rev 2001;179:156-62.
40. Lampinen M, Carlson M, Sangfelt P, et al. IL-5 and TNF-alpha participate in recruitment of eosinophils to intestinal mucosa in ulcerative colitis. Dig Dis Sci 2001;46:2004-9.
41. Lorentz A, Schwengberg S, Mierke C, et al. Human intestinal mast cells produce IL-5 in vitro upon IgE receptor cross-linking and in vivo in the course of intestinal inflammatory disease. Eur J Immunol 1999;29:1496-503.
42. Hankard GF, Brousse N, Cezard JP, et al. In situ interleukin 5 gene expression in pediatric Crohn's disease. J Pediatr Gastroenterol Nutr 1997;24:568-72.
43. Dubucquoi S, Janin A, Klein O, et al. Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease. Gut 1995;37:242-6.
44. Otamiri T, Sjodahl R. Oxygen radicals: their role in selected gastrointestinal disorders. Dig Dis 1991;9:133-41.
45. Seril DN, Liao J, Ho K, et al. Dietary iron supplementation enhances DSS-induced colitis and associated colorectal carcinoma development in mice. Dig Dis Sci 2002;47:1266-78.
46. Seril DN, Liao J, Ho K, et al. Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcystine. Carcinogenesis 2002;23:993-1001.