Survival in high-risk eyes of epithelium-deprived orthotopic corneal allografts reconstituted in vitro with syngeneic epithelium

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 2, 2003, Pages 658-664

  Hori, Junko ^a,b,c   Streilein, J Wayne ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORNEA EPITHELIUM; CORNEA TRANSPLANTATION; DELAYED HYPERSENSITIVITY; GRAFT REJECTION; GRAFT SURVIVAL; HISTOLOGY; IMMUNIZATION; IN VITRO STUDY; ISOGRAFT; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; SPLEEN CELL;

ANIMALS; CORNEAL TRANSPLANTATION; EPITHELIUM, CORNEAL; GRAFT SURVIVAL; HYPERSENSITIVITY, DELAYED; IMMUNIZATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TRANSPLANTATION, HOMOLOGOUS;

EID: 0037310098     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0399     Document Type: Article

References (30)

1. Streilein JW. Immunoregulatory mechanisms of the eye. Prog Retinal Eye Res. 1999;18:357-370.
2. Niederkorn JY. The immune privilege of corneal allografts. Transplantation. 1999;67:1503-1508.
3. The Collaborative Transplantation Studies Research Group. The Collaborative Corneal Transplantation Studies (CCTS): effectiveness of histocompatibility matching in high-risk corneal transplantation. Arch Ophthalmol. 1992;110:1392-1403.
4. Hori J, Streilein JW. Role of recipient epithelium in promoting survival of orthotopic corneal allograft in mice. Invest Ophthalmol Vis Sci. 2001;42:720-726.
5. Sonoda Y, Streilein JW. Orthotopic corneal transplantation in mice: evidence that the immunogenic rules of rejection do not apply. Transplantation. 1992;54:694-704.
6. Williams KA, Coster DJ. Penetrating corneal transplantation in the inbred rat: a new model. Invest Ophthalmol Vis Sci. 1985;26:23-30.
7. Volker-Dieben HJM, Kok-van Alphen CC, Lansbergen Q, Persijn GG. Different influences on corneal graft survival in 539 transplants. Acta Ophthalmol. 1982;60:190-202.
8. The Collaborative Transplantation Studies Research Group. Risk factors for corneal graft failure and rejection in the Collaborative Corneal Transplantation Studies (CCTS): Ophthalmology. 1994; 101:1536-1547.
9. Sano Y, Ksander BR, Streilein JW. Murine orthotopic corneal transplantation in high-risk eyes: rejection is dictated primarily by weak rather than strong alloantigens. Invest Ophthalmol Vis Sci. 1997; 38:1130-1138.
10. Sano Y, Ksander BR, Streilein JW. Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation induction. Invest Ophthalmol Vis Sci. 1995;36:2176-2185.
11. Sano Y, Okamoto S, Streilein JW. Induction of donor-specific ACAID can prolong orthotopic corneal allograft survival in "high-risk" eyes. Curr Eye Res. 1997;16:1171-1174.
12. Sonoda Y, Sano Y, Ksander B, Streilein JW. Characterization of cell-mediated immune responses elicited by orthotopic corneal allografts in mice. Invest Ophthalmol Vis Sci. 1995;36:427-434.
13. Yamada J, Streilein JW. Induction of anterior chamber-associated immune deviation by corneal allografts placed in the anterior chamber. Invest Ophthalmol Vis Sci. 1997;38:2833-2843.
14. Sonoda A, Sonoda Y, Muramatu R, Streilein, JW, Usui M. ACAID induced by allogeneic corneal tissue promotes subsequent survival of orthotopic corneal grafts. Invest Ophthalmol Vis Sci. 2000;41:790-798.
15. Hori J, Joyce N, Streilein JW. Epithelium-deficient corneal allografts display immune privilege beneath the kidney capsule. Invest Ophthalmol Vis Sci. 2000;41:443-452.
16. Hori J, Joyce N, Streilein JW. Immune privilege and immunogenicity reside among layers of the mouse cornea. Invest Ophthalmol Vis Sci. 2000;41:3032-3042.
17. Whitsett CF, Stulting RD. The distribution of HLA antigens on human corneal tissue. Invest Ophthalmol Vis Sci. 1984;25:519-524.
18. Wang HM, Kaplan HJ, Chan WC, Johnson M. The distribution and ontogeny of MHC antigens in murine ocular tissue. Invest Ophthalmol Vis Sci. 1987;28:1383-1389.
19. Treseler PA, Sanfilippo F. The expression of major histocompatibility complex and leukocyte antigens by cells in the rat cornea. Transplantation. 1986;41:248-252.
20. Hori J, Streilein JW. Dynamics of donor cell persistence and recipient cell replacement in orthotopic corneal allografts in mice. Invest Ophthalmol Vis Sci. 2001;42:1820-1828.
21. Streilein JW, Bradley D, Sano Y, Sonoda Y. Immunosuppressive properties of tissues obtained from eyes with experimentally manipulated corneas. Invest Ophthalmol Vis Sci. 1996;37:413-424.
22. Sonoda Y, Streilein JW. Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts. J Immunol. 1993; 150:1727-1734.
23. Niederkorn JY, Mellon J. Anterior chamber-associated immune deviation promotes corneal allograft survival. Invest Ophthalmol Vis Sci. 1996;37:2700-2707.
24. Collin HB. Corneal lymphatics in alloxan vascularized rabbit eyes. Invest Ophthalmol. 1966;5:1-13.
25. Collin HB. Endothelial cell lined lymphatics in the vascularized rabbit cornea. Invest Ophthalmol. 1966;5:337-354.
26. Collin HB. Ultra structure of lymphatic vessels in the vascularized rabbit cornea. Exp Eye Res. 1970;10:207-213.
27. Ksander BR, Sano Y, Streilein JW. Role of donor-specific cytotoxic T cells in rejection of corneal allografts in normal and high-risk eyes. Transplant Immunol. 1996;4:49-52.
28. Sano Y, Streilein JW, Ksander BR. Detection of minor alloantigenspecific cytotoxic T cells after rejection of murine orthotopic corneal allografts: evidence that graft antigens are recognized exclusively via the indirect pathway. Transplantation. 1999;68:963-970.
29. Sano Y, Ksander BR, Streilein JW. Analysis of primed donor-specific T cells in recipient mice bearing orthotopic corneal allografts. Transplantation. 2000;71:1302-1310.
30. Sano Y, Ksander BR, Streilein JW. Langerhans cells, orthotopic corneal allografts, and direct and indirect pathways of T-cells allorecognition. Invest Ophthalmol Vis Sci. 2000;41:1422-1431.