Anterior chamber-associated immune deviation promotes corneal allograft survival

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 13, 1996, Pages 2700-2707

  Niederkorn, Jerry Y ^a   Mellon, Jessamee ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

anterior chamber associated immune deviation (ACAID); corneal allografts; immune privilege; keratoplasty

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR EYE CHAMBER; ARTICLE; CONTROLLED STUDY; CORNEA TRANSPLANTATION; DELAYED HYPERSENSITIVITY; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; KERATOPLASTY; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SPLENECTOMY;

ANIMALS; ANTERIOR CHAMBER; CORNEAL TRANSPLANTATION; ENDOTHELIUM, CORNEAL; EPITHELIUM; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYPERSENSITIVITY, DELAYED; ISOANTIGENS; LANGERHANS CELLS; MICE; MICE, INBRED C3H; MICE, INBRED NZB; SPLEEN; SPLENECTOMY; TRANSPLANTATION, HOMOLOGOUS;

EID: 0030444098     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. The Collaborative Cornea Transplantation Studies Research Group. The collaborative corneal transplantation studies (CCTS): Effectiveness of histocompatibility matching in high-risk corneal transplantation. Arch Ophthalmol. 1992;110:1392-1403.
2. Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol. 1990;48:191-226.
3. Niederkorn JY, Peeler JS, Ross J, Callanan D. The immunogenic privilege of corneal allografts. Reg Immunol. 1989;2:117-124.
4. + cells in skin graft rejection in the mouse. Transplantation. 1987;44:273-280.
5. Rosenberg AS, Mizuochi T, Sharrow SO, Singer A. Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection. J Exp Med. 1987;165:1296-1315.
6. Sonoda Y, Streilein JW. Orthotopic corneal transplantation in mice - evidence that the immunogenetic rules of rejection do not apply. Transplantation. 1992;54:694-704.
7. Williams KA, Coster DJ. Penetrating corneal transplantation in the inbred rat. Invest Ophthalmol Vis Sci. 1985;26:23-30.
8. Callanan D, Peeler J, Niederkorn JY. Characteristics of rejection of orthotopic corneal allografts in the rat. Transplantation. 1988;45:437-443.
9. Jager MJ. Corneal Langerhans cells and ocular immunology. Reg Immunol. 1992;4:186-195.
10. Streilein JW. Unraveling immune privilege. Science. 1996;270:1158-1159.
11. Sonoda Y, Streilein JW. Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts. J Immunol, 1993;150:1727-1734.
12. She S-C, Steahly LP, Moticka EJ. Intracameral injection of allogeneic lymphocytes enhances corneal graft survival. Invest Ophthalmol Vis Sci. 1990;31:1950-1956.
13. She S-C, Moticka EJ. Ability of intracamerally inoculated B- and T-cell enriched allogeneic lymphocytes to enhance corneal allograft survival. Int Ophthalmol. 1992;17:1-7.
14. Yao W, Inoue Y, Hara Y, Kiritoshi A, Tano Y, Ohashi Y. Suppression of graft rejection in rat keratoepithelioplasty by anterior chamber inoculation of donor lymphocytes. Jpn J Ophthalmol. 1994;38:345-352.
15. He YG, McCulley JP. Growing human corneal epithelium on collagen shield and subsequent transfer to denuded cornea in vitro. Curr Eye Res. 1991;10:851-863.
16. Yue BYJT, Sugar J, Gilboy JE, Elvart JL. Growth of human corneal endothelial cells in culture. Invest Ophthalmol Vis Sci. 1989;30:248-253.
17. Wilson SE, Weng J, Blair S, He Y-G, Lloyd S. Expression of E6/E7 or SV40 large T antigen-coding oncogenes in human corneal endothelial cells indicates regulated high-proliferative capacity. Invest Ophthalmol Vis Sci. 1995;36:32-40.
18. Benson JL, Niederkorn JY. The presence of donor-derived class II positive cells abolishes immune privilege in the anterior chamber of the eye. Transplantation. 1991;51:834-838.
19. + Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigens. J Immunol. 1986;136:4362-4371.
20. She SC, Steahly LP, Moticka EJ. A method for performing full-thickness, orthotopic, penetrating keratoplasty in the mouse. Ophthalmic Surg. 1990;21:781-785.
21. He YG, Ross J, Niederkorn JY. Promotion of murine orthotopic corneal allograft survival by systemic administration of and CD4 monoclonal antibody. Invest Ophthalmol Vis Sci. 1991;32:2723-2728.
22. Holland EJ, Chan C-C, Wetzig RP, Palestine AG, Nussenblatt RB. Clinical and immunohistologic studies of corneal rejection in the rat penetrating keratoplasty model. Cornea. 1991;10:374-380.
23. He YG, Mellon J, Niederkorn JY. The effect of oral immunization on corneal allograft survival. Transplantation. 1996;61:920-926.
24. Niederkorn JY, Mayhew E, He Y-G. Alloantigens introduced into the anterior chamber of the eye induce systemic suppression of delayed hypersensitivity to third-party alloantigens through 'linked recognition.' Transplantation. 1995;60:348-354.
25. Niederkorn JY, Streilein JW. Induction of anterior chamber-associated immune deviation (ACAID) by allogeneic intraocular tumors does not require splenic metastases. J Immunol 1982;128:2470-2474.
26. Ross J, He Y-G, Pidherney M, Mellon J, Niederkorn JY. The differential effects of donor versus host Langerhans cells in the rejection of MHC-matched corneal allografts. Transplantation. 1991;52:857-861.
27. He Y-G, Niederkorn JY. Depletion of donor-derived Langerhans cells promotes corneal allograft survival. Cornea. 1996;15:82-89.
28. Katami M, White DJG, Watson PG. An analysis of corneal graft rejection in the rat. Transplant Proc. 1989;21:3147-3149.
29. 1 lymphocyte-induced immune deviation, J Immunol 1978;120:689-694.
30. Streilein JW, Niederkorn JY. Induction of anterior chamber-associated immune deviation requires an intact functional spleen. J Exp Med. 1981;153:1058-1067.
31. Lindstrom RL. Advances in corneal transplantation. N Engl J Med. 1986;315:57-59.
32. Ferguson TA, Waldrep JC, Kaplan HJ. The immune response and the eye: II: The nature of T suppressor cell induction in anterior chamber-associated immune deviation (ACAID). J Immunol. 1987;139:352-357.
33. Kosiewicz MM, Okamoto S, Miki S, Ksander BR, Shimizu T, Streilein JW. Imposing deviant immunity on the presensitized host J Immunol. 1994;153:2962-2973.
34. Joo C-K, Pepose JS, Stuart M. T-cell mediated responses in a murine model of orthotopic corneal transplantation. Invest Ophthalmol Vis Sci. 1995; 36:1530-1540.
35. Sano Y, Ksander BR, Streilein JW. Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci. 1995;36:2176-2185.
36. Pleyer U, Milani JK, Dukes A, et al. Effect of topically applied anti-CD4 monoclonal antibodies on orthotopic corneal allografts in a rat model. Invest Ophthalmol Vis Sci. 1996;36:52-61.
37. Donnelly JJ, Chan LS, Xi MS, Rockey JH. Effect of human corneal fibroblasts on lymphocyte proliferation in vitro. Exp Eye Res. 1988;47:61-70.
38. Kawashima H, Gregerson DS. Corneal endothelial cells block T cell proliferation, but not T cell activation or responsiveness to exogenous IL-2. Curr Eye Res. 1994;557-585.
39. Whitsett CF, Stulting RD. The distribution of HLA antigens on human corneal tissue. Invest Ophthalmol Vis Sci. 1984;25:519-524.
40. Fujikawa LS, Colvin RB, Bhan AK, Fuller TC, Foster CS. Expression of HLA-A/B/C and -DR locus antigens on epithelial, stromal, and endothelial cells in the human cornea. Cornea. 1982;1:213-222.
41. Williams KA, Ash JK, Coster DJ. Histocompatibility antigen and passenger cell content of normal and diseased human cornea. Transplantation. 1985; 39:265-269.